Reviewed, UniProtKB/Swiss-Prot P58708 (DALD_RALSO)

Names and origin

Protein names

Recommended name:
    D-arabinitol 4-dehydrogenase
    EC=1.1.1.11

Gene names

Name:	dalD
Ordered Locus Names:	RSc2129
ORF Names:	RS01475

Organism

Ralstonia solanacearum (Pseudomonas solanacearum) [Complete proteome] [HAMAP]

Taxonomic identifier

305 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia

Protein attributes

Sequence length	465 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-arabinitol + NAD(+) = D-xylulose + NADH.
Pathway	Carbohydrate metabolism; D-arabinitol metabolism.
Sequence similarities	Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	D-arabinitol 4-dehydrogenase activity Inferred from electronic annotation. Source: EC coenzyme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 465	465	D-arabinitol 4-dehydrogenase		PRO_0000170736

Sequences

	Sequence		Length	Mass (Da)
	P58708-1 [UniParc]. Last modified January 31, 2002. Version 1. Checksum: 47095425D4836342	FASTA	465	50,630
	10 20 30 40 50 60 MTRSSLARAP VLLHIGAGSF HRAHQAWYLH RVNAAVPPGE RWTLTVGNIR DDMHATLAAL 70 80 90 100 110 120 AAQQGAYTLE TVTPQGERAY ETIRSIARVL PWSADLAALI NTGADPACRI VSFTVTEGGY 130 140 150 160 170 180 YLDEHDRLDV THPDLAADLR GARSTLYGAL AALLAERRQR GAGPLTLQSC DNLRSNGARF 190 200 210 220 230 240 RAGMRAFLAL RGDAALLAWF DANVSCPSAM VDRITPRPTD DVRTRVHAAT GVDDRCPVMG 250 260 270 280 290 300 ESFIQWVIED NFIAGRPAWE IAGAEIVADV HPYEEAKIRI LNATHSCIAW AGTLAGLTYI 310 320 330 340 350 360 HEGMRDAAIY RFAYDYVTDD VIPCLTPSPL DLERYRDVVL ERFGNPYVLD TNQRVAADGF 370 380 390 400 410 420 SKIPGFIAPT LAECFARGAD PVATAVLPAL FLGFLEGWAR GTLPYVYQDG VMDGAAARSI 430 440 450 460 VEAPDSVAAF CSDRQLWGSL AGRDALVQAV RAGRARVEAW RAARR

References

[1]

"Genome sequence of the plant pathogen Ralstonia solanacearum." Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A. , Robert C., Saurin W., Schiex T., Siguier P., Thebault P., Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A. Nature 415:497-502(2002) [PubMed: 11823852] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GMI1000.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL646052 Genomic DNA. Translation: CAD15836.1.
RefSeq	NP_520250.1.
3D structure databases
HSSP	HSSP built from PDB template 1LJ8 based on UniProtKB O08355.
ModBase	Search...
Genome annotation databases
GeneID	1220971.
GenomeReviews	Gene locus RSc2129 in contig AL646052_GR.
KEGG	rso:RSc2129.
NMPDR	fig|267608.1.peg.2129.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P58708.
Enzyme and pathway databases
BioCyc	RSOL267608:RSC2129-MON.
Family and domain databases
InterPro	IPR013328. DHase_multihelical. IPR013118. Mannitol_DHase_C. IPR000669. Mannitol_DHase_core. IPR013131. Mannitol_DHase_N. IPR016040. NAD(P)-bd. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
Pfam	PF01232. Mannitol_dh. 1 hit. PF08125. Mannitol_dh_C. 1 hit. [Graphical view]
PRINTS	PR00084. MTLDHDRGNASE.
PROSITE	PS00974. MANNITOL_DHGENASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DALD_RALSO

Accession

Primary (citable) accession number: P58708

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 31, 2002
Last sequence update:	January 31, 2002
Last modified:	November 25, 2008
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)