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P58642

- PYRF_RALSO

UniProt

P58642 - PYRF_RALSO

Protein

Orotidine 5'-phosphate decarboxylase

Gene

pyrF

Organism
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (23 Jan 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Orotidine 5'-phosphate = UMP + CO2.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei95 – 951Proton donorBy similarity

    GO - Molecular functioni

    1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
    2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Pyrimidine biosynthesis

    Enzyme and pathway databases

    BioCyciRSOL267608:GCVU-2815-MONOMER.
    UniPathwayiUPA00070; UER00120.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Orotidine 5'-phosphate decarboxylase (EC:4.1.1.23)
    Alternative name(s):
    OMP decarboxylase
    Short name:
    OMPDCase
    Short name:
    OMPdecase
    Gene namesi
    Name:pyrF
    Ordered Locus Names:RSc2773
    ORF Names:RS00074
    OrganismiRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
    Taxonomic identifieri267608 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
    ProteomesiUP000001436: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 271271Orotidine 5'-phosphate decarboxylasePRO_0000134633Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi267608.RSc2773.

    Structurei

    3D structure databases

    ProteinModelPortaliP58642.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0284.
    HOGENOMiHOG000245747.
    KOiK01591.
    OMAiCRTSNAG.
    OrthoDBiEOG6DZF33.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_01215. OMPdecase_type2.
    InterProiIPR013785. Aldolase_TIM.
    IPR018089. OMPdecase_AS.
    IPR011995. OMPdecase_type-2.
    IPR001754. OMPdeCOase_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00215. OMPdecase. 1 hit.
    [Graphical view]
    SMARTiSM00934. OMPdecase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.
    TIGRFAMsiTIGR02127. pyrF_sub2. 1 hit.
    PROSITEiPS00156. OMPDECASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P58642-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRFTEQLAAA WQRNNSLLCV GLDPDPARLP ASLTTSGGAI FSFCRAIVDA    50
    TADLVCAFKP QIAYFASQRA EDQLEQLIAY IHEAYPGIPV ILDAKRGDIG 100
    STAEHYAKEA FERYQADAVT VSPYMGFDSM QPYLVHPDKG VIVLCRTSNA 150
    GGSDVQFLET NGRPVYQVVA ERARDAWNTS GQMGLVVGAT FPQEIRRVRE 200
    IVGDMPLLIP GIGVQGGDIE ATVRAGRTAD GTGMMINSSR AILYASSDSD 250
    FADAARGVAQ ATRDQINQYR N 271
    Length:271
    Mass (Da):29,344
    Last modified:January 23, 2002 - v1
    Checksum:i4441A0067094001E
    GO

    Sequence cautioni

    The sequence CAD16480.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL646052 Genomic DNA. Translation: CAD16480.1. Different initiation.
    RefSeqiNP_520894.1. NC_003295.1.

    Genome annotation databases

    EnsemblBacteriaiCAD16480; CAD16480; RSc2773.
    GeneIDi1221620.
    KEGGirso:RSc2773.
    PATRICi20264259. VBIRalSol70888_2821.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL646052 Genomic DNA. Translation: CAD16480.1 . Different initiation.
    RefSeqi NP_520894.1. NC_003295.1.

    3D structure databases

    ProteinModelPortali P58642.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 267608.RSc2773.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAD16480 ; CAD16480 ; RSc2773 .
    GeneIDi 1221620.
    KEGGi rso:RSc2773.
    PATRICi 20264259. VBIRalSol70888_2821.

    Phylogenomic databases

    eggNOGi COG0284.
    HOGENOMi HOG000245747.
    KOi K01591.
    OMAi CRTSNAG.
    OrthoDBi EOG6DZF33.

    Enzyme and pathway databases

    UniPathwayi UPA00070 ; UER00120 .
    BioCyci RSOL267608:GCVU-2815-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_01215. OMPdecase_type2.
    InterProi IPR013785. Aldolase_TIM.
    IPR018089. OMPdecase_AS.
    IPR011995. OMPdecase_type-2.
    IPR001754. OMPdeCOase_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00215. OMPdecase. 1 hit.
    [Graphical view ]
    SMARTi SM00934. OMPdecase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    TIGRFAMsi TIGR02127. pyrF_sub2. 1 hit.
    PROSITEi PS00156. OMPDECASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GMI1000.

    Entry informationi

    Entry nameiPYRF_RALSO
    AccessioniPrimary (citable) accession number: P58642
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 23, 2002
    Last sequence update: January 23, 2002
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3