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Protein

Glucokinase

Gene

glk

Organism
Yersinia pestis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 136ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYPES214092:GKDD-2932-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:YPO2977, y1505, YP_2602
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815 Componenti: Chromosome UP000001019 Componenti: Chromosome UP000002490 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 323323GlucokinasePRO_0000215145Add
BLAST

Proteomic databases

PRIDEiP58619.

Interactioni

Protein-protein interaction databases

STRINGi187410.y1505.

Structurei

3D structure databases

ProteinModelPortaliP58619.
SMRiP58619. Positions 2-321.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

P58619-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTYALVGDV GGTNARLALC AVATGEILQA KTYSGLEYES LEDVIKQYLS
60 70 80 90 100
EHQAKVTDAC IAIACPITGD WVAMTNHTWA FSIAAMQQNL GLDHLEVIND
110 120 130 140 150
FTAVSMAIPV LPAQDVLQFG GTQPQPGKPV AVYGAGTGLG VAHLVNVDRR
160 170 180 190 200
WISLAGEGGH VDFAPNSEEE DQILAVLRQE LGHVSAERVL SGPGLVNLYR
210 220 230 240 250
AIVISDARLP EKLAPKDITA RALADSCTDC RRALSLFCVI MGRFGGNLAL
260 270 280 290 300
NLSTFGGVYI AGGIVPRFME FFKASGFRAA FEDKGRFKDF LQDIPVYMIT
310 320
HPQPGLLGAG AYLRQKLGYE LSS
Length:323
Mass (Da):34,664
Last modified:January 23, 2002 - v1
Checksum:iA2465D600781CE37
GO

Sequence cautioni

The sequence AAM85076.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL21581.1.
AE009952 Genomic DNA. Translation: AAM85076.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS62795.1.
PIRiAB0362.
RefSeqiWP_002211615.1. NZ_KN150727.1.
YP_002347901.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM85076; AAM85076; y1505.
AAS62795; AAS62795; YP_2602.
GeneIDi1175794.
KEGGiype:YPO2977.
ypj:CH55_4102.
ypk:y1505.
ypl:CH46_2130.
ypm:YP_2602.
ypv:BZ15_556.
ypw:CH59_3099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL21581.1.
AE009952 Genomic DNA. Translation: AAM85076.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS62795.1.
PIRiAB0362.
RefSeqiWP_002211615.1. NZ_KN150727.1.
YP_002347901.1. NC_003143.1.

3D structure databases

ProteinModelPortaliP58619.
SMRiP58619. Positions 2-321.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187410.y1505.

Proteomic databases

PRIDEiP58619.

Protocols and materials databases

DNASUi1146452.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM85076; AAM85076; y1505.
AAS62795; AAS62795; YP_2602.
GeneIDi1175794.
KEGGiype:YPO2977.
ypj:CH55_4102.
ypk:y1505.
ypl:CH46_2130.
ypm:YP_2602.
ypv:BZ15_556.
ypw:CH59_3099.

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.

Enzyme and pathway databases

BioCyciYPES214092:GKDD-2932-MONOMER.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiGLK_YERPE
AccessioniPrimary (citable) accession number: P58619
Secondary accession number(s): Q0WCT7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: January 23, 2002
Last modified: July 22, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.