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P58619

- GLK_YERPE

UniProt

P58619 - GLK_YERPE

Protein

Glucokinase

Gene

glk

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (23 Jan 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi8 – 136ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. glucokinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciYPES214092:GKDD-2932-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
    Alternative name(s):
    Glucose kinaseUniRule annotation
    Gene namesi
    Name:glkUniRule annotation
    Ordered Locus Names:YPO2977, y1505, YP_2602
    OrganismiYersinia pestis
    Taxonomic identifieri632 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 323323GlucokinasePRO_0000215145Add
    BLAST

    Proteomic databases

    PRIDEiP58619.

    Interactioni

    Protein-protein interaction databases

    STRINGi214092.YPO2977.

    Structurei

    3D structure databases

    ProteinModelPortaliP58619.
    SMRiP58619. Positions 2-321.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the bacterial glucokinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0837.
    HOGENOMiHOG000274469.
    KOiK00845.
    OMAiFNEANVG.
    OrthoDBiEOG64BQ47.

    Family and domain databases

    HAMAPiMF_00524. Glucokinase.
    InterProiIPR003836. Glucokinase.
    [Graphical view]
    PfamiPF02685. Glucokinase. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00749. glk. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P58619-1 [UniParc]FASTAAdd to Basket

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    MTTYALVGDV GGTNARLALC AVATGEILQA KTYSGLEYES LEDVIKQYLS    50
    EHQAKVTDAC IAIACPITGD WVAMTNHTWA FSIAAMQQNL GLDHLEVIND 100
    FTAVSMAIPV LPAQDVLQFG GTQPQPGKPV AVYGAGTGLG VAHLVNVDRR 150
    WISLAGEGGH VDFAPNSEEE DQILAVLRQE LGHVSAERVL SGPGLVNLYR 200
    AIVISDARLP EKLAPKDITA RALADSCTDC RRALSLFCVI MGRFGGNLAL 250
    NLSTFGGVYI AGGIVPRFME FFKASGFRAA FEDKGRFKDF LQDIPVYMIT 300
    HPQPGLLGAG AYLRQKLGYE LSS 323
    Length:323
    Mass (Da):34,664
    Last modified:January 23, 2002 - v1
    Checksum:iA2465D600781CE37
    GO

    Sequence cautioni

    The sequence AAM85076.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL21581.1.
    AE009952 Genomic DNA. Translation: AAM85076.1. Different initiation.
    AE017042 Genomic DNA. Translation: AAS62795.1.
    PIRiAB0362.
    RefSeqiNP_668825.1. NC_004088.1.
    NP_993918.1. NC_005810.1.
    YP_002347901.1. NC_003143.1.

    Genome annotation databases

    EnsemblBacteriaiAAM85076; AAM85076; y1505.
    AAS62795; AAS62795; YP_2602.
    GeneIDi1146452.
    1175794.
    2765257.
    KEGGiype:YPO2977.
    ypk:y1505.
    ypm:YP_2602.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL21581.1 .
    AE009952 Genomic DNA. Translation: AAM85076.1 . Different initiation.
    AE017042 Genomic DNA. Translation: AAS62795.1 .
    PIRi AB0362.
    RefSeqi NP_668825.1. NC_004088.1.
    NP_993918.1. NC_005810.1.
    YP_002347901.1. NC_003143.1.

    3D structure databases

    ProteinModelPortali P58619.
    SMRi P58619. Positions 2-321.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 214092.YPO2977.

    Proteomic databases

    PRIDEi P58619.

    Protocols and materials databases

    DNASUi 1146452.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM85076 ; AAM85076 ; y1505 .
    AAS62795 ; AAS62795 ; YP_2602 .
    GeneIDi 1146452.
    1175794.
    2765257.
    KEGGi ype:YPO2977.
    ypk:y1505.
    ypm:YP_2602.

    Phylogenomic databases

    eggNOGi COG0837.
    HOGENOMi HOG000274469.
    KOi K00845.
    OMAi FNEANVG.
    OrthoDBi EOG64BQ47.

    Enzyme and pathway databases

    BioCyci YPES214092:GKDD-2932-MONOMER.

    Family and domain databases

    HAMAPi MF_00524. Glucokinase.
    InterProi IPR003836. Glucokinase.
    [Graphical view ]
    Pfami PF02685. Glucokinase. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00749. glk. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CO-92 / Biovar Orientalis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KIM10+ / Biovar Mediaevalis.
    3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
      Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
      , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
      DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 91001 / Biovar Mediaevalis.

    Entry informationi

    Entry nameiGLK_YERPE
    AccessioniPrimary (citable) accession number: P58619
    Secondary accession number(s): Q0WCT7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 23, 2002
    Last sequence update: January 23, 2002
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3