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P58619

- GLK_YERPE

UniProt

P58619 - GLK_YERPE

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Protein
Glucokinase
Gene
glk, YPO2977, y1505, YP_2602
Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 136ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYPES214092:GKDD-2932-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucokinase (EC:2.7.1.2)
Alternative name(s):
Glucose kinase
Gene namesi
Name:glk
Ordered Locus Names:YPO2977, y1505, YP_2602
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 323323GlucokinaseUniRule annotation
PRO_0000215145Add
BLAST

Proteomic databases

PRIDEiP58619.

Interactioni

Protein-protein interaction databases

STRINGi214092.YPO2977.

Structurei

3D structure databases

ProteinModelPortaliP58619.
SMRiP58619. Positions 2-321.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiFNEANVG.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

P58619-1 [UniParc]FASTAAdd to Basket

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MTTYALVGDV GGTNARLALC AVATGEILQA KTYSGLEYES LEDVIKQYLS    50
EHQAKVTDAC IAIACPITGD WVAMTNHTWA FSIAAMQQNL GLDHLEVIND 100
FTAVSMAIPV LPAQDVLQFG GTQPQPGKPV AVYGAGTGLG VAHLVNVDRR 150
WISLAGEGGH VDFAPNSEEE DQILAVLRQE LGHVSAERVL SGPGLVNLYR 200
AIVISDARLP EKLAPKDITA RALADSCTDC RRALSLFCVI MGRFGGNLAL 250
NLSTFGGVYI AGGIVPRFME FFKASGFRAA FEDKGRFKDF LQDIPVYMIT 300
HPQPGLLGAG AYLRQKLGYE LSS 323
Length:323
Mass (Da):34,664
Last modified:January 23, 2002 - v1
Checksum:iA2465D600781CE37
GO

Sequence cautioni

The sequence AAM85076.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL21581.1.
AE009952 Genomic DNA. Translation: AAM85076.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS62795.1.
PIRiAB0362.
RefSeqiNP_668825.1. NC_004088.1.
NP_993918.1. NC_005810.1.
YP_002347901.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM85076; AAM85076; y1505.
AAS62795; AAS62795; YP_2602.
GeneIDi1146452.
1175794.
2765257.
KEGGiype:YPO2977.
ypk:y1505.
ypm:YP_2602.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL21581.1 .
AE009952 Genomic DNA. Translation: AAM85076.1 . Different initiation.
AE017042 Genomic DNA. Translation: AAS62795.1 .
PIRi AB0362.
RefSeqi NP_668825.1. NC_004088.1.
NP_993918.1. NC_005810.1.
YP_002347901.1. NC_003143.1.

3D structure databases

ProteinModelPortali P58619.
SMRi P58619. Positions 2-321.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 214092.YPO2977.

Proteomic databases

PRIDEi P58619.

Protocols and materials databases

DNASUi 1146452.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM85076 ; AAM85076 ; y1505 .
AAS62795 ; AAS62795 ; YP_2602 .
GeneIDi 1146452.
1175794.
2765257.
KEGGi ype:YPO2977.
ypk:y1505.
ypm:YP_2602.

Phylogenomic databases

eggNOGi COG0837.
HOGENOMi HOG000274469.
KOi K00845.
OMAi FNEANVG.
OrthoDBi EOG64BQ47.

Enzyme and pathway databases

BioCyci YPES214092:GKDD-2932-MONOMER.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiGLK_YERPE
AccessioniPrimary (citable) accession number: P58619
Secondary accession number(s): Q0WCT7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: January 23, 2002
Last modified: June 11, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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