P58616 (GLK_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucokinase
EC=2.7.1.2

Alternative name(s):
Glucose kinase

Gene names

Name:	glk
Ordered Locus Names:	alr2973

Organism

Nostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the bacterial glucokinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP glucokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 342	342	Glucokinase HAMAP-Rule MF_00524		PRO_0000215119
Regions
	Nucleotide binding	7 – 12	6	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P58616 [UniParc]. Last modified January 23, 2002. Version 1. Checksum: FC25B5C26750440B	FASTA	342	37,064
	10 20 30 40 50 60 MTLLLAGDIG GTKTILRLVE ISNSSELHNI YEESYQSGDF PDLVPMVQQF LVKANIPSHP 70 80 90 100 110 120 EKACFAIAGP VVNNTAKLTN LVWFLDTERL AQELSIPFIS LINDFAAVGY GIFGLNKQDL 130 140 150 160 170 180 LTLQAGKHQP EAPIAIIGAG TGLGQGFLIK QGNQYQVFPS EGGHADFAPR NELEFQLLKY 190 200 210 220 230 240 LLDKHDIQRV SVERVVSGQG IVAIYQFLRD RKLATESPEI AQVVRTWEQQ AGQAEKTVDP 250 260 270 280 290 300 GAAIGKAAVQ GSDRLSEQAL QLFIDAYGAE AGNLALKLLP YGGLYIAGGI APKILPLIEN 310 320 330 340 SNFLLNFSQK GRMRPLLAEI PVHIILNQQV GLIGAALCAA RL

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7120 / UTEX 2576.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000019 Genomic DNA. Translation: BAB74672.1.
PIR	AF2177.
RefSeq	NP_487013.1. NC_003272.1.
3D structure databases
ProteinModelPortal	P58616.
ModBase	Search...
Protein-protein interaction databases
STRING	103690.alr2973.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAB74672; BAB74672; BAB74672.
GeneID	1106571.
KEGG	ana:alr2973.
PATRIC	22776254. VBINosSp37423_3587.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0837.
HOGENOM	HOG000274470.
KO	K00845.
OMA	FADKGCM.
ProtClustDB	PRK00292.
Family and domain databases
HAMAP	MF_00524. Glucokinase.
InterPro	IPR003836. Glucokinase. [Graphical view]
Pfam	PF02685. Glucokinase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00749. glk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLK_NOSS1

Accession

Primary (citable) accession number: P58616

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	January 23, 2002
Last modified:	May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program