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P58599 (GUN_RALSO) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoglucanase

EC=3.2.1.4
Alternative name(s):
Cellulase
Endo-1,4-beta-glucanase
Gene names
Name:egl
Ordered Locus Names:RSp0162
ORF Names:RS05516
Encoded onPlasmid megaplasmid Rsp
OrganismRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) [Complete proteome] [HAMAP]
Taxonomic identifier267608 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia

Protein attributes

Sequence length424 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Subcellular location

Cell membrane; Lipid-anchor Probable.

Sequence similarities

Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Sequence caution

The sequence CAD17313.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentCell membrane
Membrane
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMLipoprotein
Palmitate
Zymogen
   Technical termComplete proteome
Plasmid
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncellulase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 By similarity
Propeptide20 – 4324 By similarity
PRO_0000007867
Chain44 – 424381Endoglucanase
PRO_0000007868

Sites

Active site2471Proton donor By similarity
Active site3591Nucleophile By similarity

Amino acid modifications

Lipidation201N-palmitoyl cysteine By similarity
Lipidation201S-diacylglycerol cysteine By similarity

Sequences

Sequence LengthMass (Da)Tools
P58599 [UniParc].

Last modified January 23, 2002. Version 1.
Checksum: 5BF0D161AB7C87EF

FASTA42445,081
        10         20         30         40         50         60 
MHRCMPLVAA SMAALMLAGC GGGDGDTTLS TAAATDTTTL KTAATTSISP LWLTIAKDSA 

        70         80         90        100        110        120 
AFTVSGTRTV RYGAGSAWVA KSMSGTGQCT AAFFGKDPAA GVAKVCQVAQ GTGTLLWRGV 

       130        140        150        160        170        180 
SLAGAEFGEG SLPGTYGSNY IYPSADSATY YKNKGMNLVR LPFRWERLQP TLNQALDANE 

       190        200        210        220        230        240 
LSRLTGFVNA VTAAGQTVLL DPHNYARYYG NVIGSSAVPN SAYADFWRRV ATQFKGNARV 

       250        260        270        280        290        300 
IFGLMNEPNS MPTEQWLSGA NAALAAIRSA NASNVVFVPG NAWTGAHSWN QNWYGTPNGT 

       310        320        330        340        350        360 
VMKGINDPGR NLVFEVHQYL DGDSSGQSAS CVSATIGAER LQDFTNWLRS NGYRGFLGEF 

       370        380        390        400        410        420 
GAASNDTCNQ AVANMLTFVK NNADVWTGWA WWAGGPWWGG YMYSIEPSNG VDKPQMSVLA 


PYLK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL646053 Genomic DNA. Translation: CAD17313.1. Different initiation.
RefSeqNP_521723.1. NC_003296.1.

3D structure databases

ProteinModelPortalP58599.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267608.RSp0162.

Protein family/group databases

CAZyGH5. Glycoside Hydrolase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD17313; CAD17313; RSp0162.
GeneID1222565.
KEGGrso:RSp0162.
PATRIC20265911. VBIRalSol70888_3628.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2730.
HOGENOMHOG000111120.
KOK01179.
OMAWTYWAAG.
OrthoDBEOG6677NC.
ProtClustDBCLSK2753836.

Enzyme and pathway databases

BioCycRSOL267608:GCVU-3665-MONOMER.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUN_RALSO
AccessionPrimary (citable) accession number: P58599
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: January 23, 2002
Last modified: November 13, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries