P58596 (EPSP_RALSO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable low molecular weight protein-tyrosine-phosphatase EpsP
EC=3.1.3.48

Gene names

Name:	epsP
Ordered Locus Names:	RSp1019
ORF Names:	RS02353

Encoded on

Plasmid megaplasmid Rsp

Organism

Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) [Complete proteome] [HAMAP]

Taxonomic identifier

267608 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia › Ralstonia solanacearum

Protein attributes

Sequence length	145 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May be involved in assembly or function of the EPS I polymerization/export complex and/or the EpsB ATPase. Alternatively it may function in the removal of the terminal phosphate from C55-isoprenyl pyrophosphate in order to recycle the C55-isoprenyl phosphate lipid carrier used in the synthesis of polysaccharide repeat units By similarity.
Catalytic activity	Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
Pathway	Glycan metabolism; exopolysaccharide biosynthesis.
Sequence similarities	Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological_process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW peptidyl-tyrosine dephosphorylation Inferred from electronic annotation. Source: GOC
Molecular_function	protein tyrosine phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 145	145	Probable low molecular weight protein-tyrosine-phosphatase EpsP		PRO_0000046570
Sites
	Active site	9	1	Nucleophile By similarity
	Active site	14	1	By similarity
	Active site	114	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	P58596 [UniParc]. Last modified January 23, 2002. Version 1. Checksum: 2873645F50134AA9	FASTA	145	15,719
	10 20 30 40 50 60 MIKTILVVCI GNICRSPMAQ ALLRQSLPGV SVISAGIGAL SGYPADPSAV EVMAHHGIDI 70 80 90 100 110 120 SEHRAQQLTG SLVSRADLIL VMDGAQKQEI QSRHPAKTGS VFRLGEMEQF DIADPYRKQL 130 140 TAFEEALEMI QRGVDAWVPR IRALG

References

[1]

"Genome sequence of the plant pathogen Ralstonia solanacearum." Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A. , Robert C., Saurin W., Schiex T., Siguier P., Thebault P., Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A. Nature 415:497-502(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GMI1000.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL646053 Genomic DNA. Translation: CAD18170.1.
RefSeq	NP_522580.1. NC_003296.1.
3D structure databases
ProteinModelPortal	P58596.
ModBase	Search...
Protein-protein interaction databases
STRING	267608.RSp1019.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAD18170; CAD18170; RSp1019.
GeneID	1223331.
KEGG	rso:RSp1019.
PATRIC	20267665. VBIRalSol70888_4500.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000273091.
KO	K01104.
OMA	VMEKKHI.
ProtClustDB	CLSK566613.
Enzyme and pathway databases
UniPathway	UPA00631.
Family and domain databases
InterPro	IPR023485. Ptyr_pPase_SF. IPR000106. Tyr_phospatase/Ars_reductase. IPR017867. Tyr_phospatase_low_mol_wt. [Graphical view]
PANTHER	PTHR11717. PTHR11717. 1 hit.
Pfam	PF01451. LMWPc. 1 hit. [Graphical view]
PRINTS	PR00719. LMWPTPASE.
SMART	SM00226. LMWPc. 1 hit. [Graphical view]
SUPFAM	SSF52788. Tyr_Pase_low_mol_wt. 1 hit.
ProtoNet	Search...
Other
DrugBank	DB00626. Bacitracin.

Entry information

Entry name

EPSP_RALSO

Accession

Primary (citable) accession number: P58596

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	January 23, 2002
Last modified:	May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program