P58549 (FXYD7_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
FXYD domain-containing ion transport regulator 7

Gene names

Name:

FXYD7

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	80 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the FXYD family.

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Ionic channel
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ion channel activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 80	80	FXYD domain-containing ion transport regulator 7		PRO_0000148190
Regions
	Transmembrane	24 – 46	23	Helical; Potential
Amino acid modifications
	Modified residue	65	1	Phosphoserine By similarity
	Modified residue	73	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	P58549 [UniParc]. Last modified January 23, 2002. Version 1. Checksum: 130DAC482EFF1939	FASTA	80	8,524
	10 20 30 40 50 60 MATPTQTPTK APEEPDPFYY DYNTVQTVGM TLATILFLLG ILIVISKKVK CRKADSRSES 70 80 PTCKSCKSEL PSSAPGGGGV

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Uterus.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC018619 mRNA. Translation: AAH18619.1.
IPI	IPI00067920.
RefSeq	NP_071289.1. NM_022006.1.
UniGene	Hs.134729.
3D structure databases
ProteinModelPortal	P58549.
SMR	P58549. Positions 10-78.
ModBase	Search...
Protein-protein interaction databases
STRING	P58549.
PTM databases
PhosphoSite	P58549.
Polymorphism databases
DMDM	20138168.
Proteomic databases
PRIDE	P58549.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000270310; ENSP00000270310; ENSG00000221946.
GeneID	53822.
KEGG	hsa:53822.
UCSC	uc002nye.1. human.
Organism-specific databases
CTD	53822.
GeneCards	GC19P035634.
HGNC	HGNC:4034. FXYD7.
HPA	HPA026916.
MIM	606684. gene.
neXtProt	NX_P58549.
PharmGKB	PA28450.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG21356.
GeneTree	ENSGT00570000080636.
HOVERGEN	HBG051679.
InParanoid	P58549.
OMA	LSKKVKC.
OrthoDB	EOG45B1H6.
PhylomeDB	P58549.
Gene expression databases
ArrayExpress	P58549.
Bgee	P58549.
CleanEx	HS_FXYD7.
Genevestigator	P58549.
GermOnline	ENSG00000142290. Homo sapiens.
Family and domain databases
InterPro	IPR000272. Ion-transport_regulator_FXYD. [Graphical view]
KO	K13364.
Pfam	PF02038. ATP1G1_PLM_MAT8. 1 hit. [Graphical view]
ProDom	PD005989. PD005989. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS01310. FXYD. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	56128.
SOURCE	Search...

Entry information

Entry name

FXYD7_HUMAN

Accession

Primary (citable) accession number: P58549

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	January 23, 2002
Last modified:	January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.