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Protein

Ribulokinase

Gene

araB

Organism
Yersinia pestis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.UniRule annotation

Pathwayi: L-arabinose degradation via L-ribulose

This protein is involved in step 2 of the subpathway that synthesizes D-xylulose 5-phosphate from L-arabinose (bacterial route).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. L-arabinose isomerase (araA), L-arabinose isomerase (araA)
  2. Ribulokinase (araB), Ribulokinase (araB)
  3. no protein annotated in this organism
This subpathway is part of the pathway L-arabinose degradation via L-ribulose, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-xylulose 5-phosphate from L-arabinose (bacterial route), the pathway L-arabinose degradation via L-ribulose and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processArabinose catabolism, Carbohydrate metabolism
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00145; UER00566

Names & Taxonomyi

Protein namesi
Recommended name:
RibulokinaseUniRule annotation (EC:2.7.1.16UniRule annotation)
Gene namesi
Name:araBUniRule annotation
Ordered Locus Names:YPO2254, y2095, YP_2050
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000815 Componenti: Chromosome
  • UP000001019 Componenti: Chromosome
  • UP000002490 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001983771 – 563RibulokinaseAdd BLAST563

Proteomic databases

PaxDbiP58543
PRIDEiP58543

Interactioni

Protein-protein interaction databases

IntActiP58543, 6 interactors
STRINGi187410.y2095

Structurei

3D structure databases

ProteinModelPortaliP58543
SMRiP58543
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribulokinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EF1 Bacteria
COG1069 LUCA
HOGENOMiHOG000236883
KOiK00853
OMAiGVWGPYK

Family and domain databases

CDDicd07781 FGGY_RBK, 1 hit
HAMAPiMF_00520 Ribulokinase, 1 hit
InterProiView protein in InterPro
IPR018485 Carb_kinase_FGGY_C
IPR018484 Carb_kinase_FGGY_N
IPR005929 Ribulokinase
PfamiView protein in Pfam
PF02782 FGGY_C, 1 hit
PF00370 FGGY_N, 1 hit
TIGRFAMsiTIGR01234 L-ribulokinase, 1 hit

Sequencei

Sequence statusi: Complete.

P58543-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISADGAIAL GLDFGSDSVR VLAVDCQHGT EIDTEVVYYP RWKKGLYCQA
60 70 80 90 100
AQNQFRHHPL DYIEAMEQAI RQMVKRLSEE QRQHIVGIGV DSTGSTPAPI
110 120 130 140 150
DEQGQVLALR PDFADNPNAM FVLWKDHTAI EEAEEINRLC RSGEFADYSR
160 170 180 190 200
YIGGVYSSEW FWAKILHVTR ADVAVREAAV SWIELCDWVP ALLSGTTAPQ
210 220 230 240 250
DIQRGRCSAG HKSLWHPSWG GLPPRAFLAA LDTSLVNDLD YPMFTDTYTA
260 270 280 290 300
ERPVGQITAE WAERLGLPTT VILSGGAFDC HMGAVGAGAQ PYTLVKVIGT
310 320 330 340 350
STCDILIADD QRVGDRAIAG ICGQVEGSVL PGWIGMEAGQ SAFGDMYAWF
360 370 380 390 400
SNLLSWPLHQ AALTQPEWQP QLKQIESNLL ASLTRAWAQN PSLDHLPVVL
410 420 430 440 450
DWFNGRRTPN ANQRLKGVIT DLNLGTDAPT LFGGFIAATA FGARAIMECF
460 470 480 490 500
EQQDIPIDNV LALGGIARKS PVIMQVCADV MNRPLQIVAS DQCCALGAAI
510 520 530 540 550
FAAVAAGAHD DVPTAQRHMA CNIERTLIPD PVQVVRYQQL YQRYQQWCHT
560
AEPHYAPVTK VIH
Length:563
Mass (Da):61,833
Last modified:January 23, 2002 - v1
Checksum:i88EF1E0B00A5414E
GO

Sequence cautioni

The sequence AAM85658 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAS62264 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAL20881 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA Translation: CAL20881.1 Different initiation.
AE009952 Genomic DNA Translation: AAM85658.1 Different initiation.
AE017042 Genomic DNA Translation: AAS62264.1 Different initiation.
PIRiAF0274
RefSeqiYP_002347221.1, NC_003143.1

Genome annotation databases

EnsemblBacteriaiAAM85658; AAM85658; y2095
AAS62264; AAS62264; YP_2050
GeneIDi1175085
KEGGiype:YPO2254
ypk:y2095
ypm:YP_2050
PATRICifig|214092.21.peg.2650

Similar proteinsi

Entry informationi

Entry nameiARAB_YERPE
AccessioniPrimary (citable) accession number: P58543
Secondary accession number(s): Q0WER7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: January 23, 2002
Last modified: May 23, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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