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P58478 (HTPG_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chaperone protein HtpG
Alternative name(s):
Heat shock protein HtpG
High temperature protein G
Gene names
Name:htpG
Ordered Locus Names:RC1302
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length621 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Molecular chaperone. Has ATPase activity By similarity. HAMAP-Rule MF_00505

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00505

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00505.

Sequence similarities

Belongs to the heat shock protein 90 family.

Ontologies

Keywords
   Biological processStress response
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 621621Chaperone protein HtpG HAMAP-Rule MF_00505
PRO_0000063010

Regions

Region1 – 328328A; substrate-binding By similarity
Region329 – 544216B By similarity
Region545 – 62177C By similarity

Sequences

Sequence LengthMass (Da)Tools
P58478 [UniParc].

Last modified December 13, 2001. Version 1.
Checksum: FF6E5B352DD8F017

FASTA62170,804
        10         20         30         40         50         60 
MIQEKKKFDA EVGKILNLMI HSLYSNKEIF MRELISNASD ACDKLRYLSQ SNSELVAGDS 

        70         80         90        100        110        120 
NFKITVKVDK DHRQIIIRDN GIGMNKDDLI ENLGTIARSG TANFLKSLSG DSKKDNMLIG 

       130        140        150        160        170        180 
QFGVGFYSSF MVADKVTVTS RKAGEDKVHI WESDGLGEYT VSDSDKEFTR GTEIVLHIKK 

       190        200        210        220        230        240 
EEDTFLDHFR LKHIVKSYSD HIAVPIYFFD EAGNNEIQLN SASALWTRPK SEITEEQYKE 

       250        260        270        280        290        300 
FYKSLSYAID DPWITMHNKN EGAIEFTNLL FIPSSKTFDL FHPDRKRRVK LYIKRVFISD 

       310        320        330        340        350        360 
ENIDLIPSYL RFLRGVVDSE DLPLNISRES LQHNSVLEKI KNAITKRVLG ELRKKKEESP 

       370        380        390        400        410        420 
EEYNKFWANF GGALKEGLCE ATTNHEKLLE VCIFRSALHN KMISLDEYIA NFKEGQSTIY 

       430        440        450        460        470        480 
YLSGDNPDKL LSSPQIEGLL SKKIDVLLFT DTVDDFWVNV NSKYKEHAIK SATRSDIDVE 

       490        500        510        520        530        540 
QTTSQSEEKN TDSTKSNDEY KLLTDYFKET LGELVKEVKI SKKLTSSPAC LAVSDAAMDI 

       550        560        570        580        590        600 
RMERFLIEQK QIANASAKNL ELNPKNKIIE KIFNDLKANN KNNEELVNLI FDQACILEGE 

       610        620 
PVADTGAFSK RLNDIVQKAI L 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL03840.1.
PIRF97862.
RefSeqNP_360939.1. NC_003103.1.

3D structure databases

ProteinModelPortalP58478.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC1302.

Proteomic databases

PRIDEP58478.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL03840; AAL03840; RC1302.
GeneID928452.
KEGGrco:RC1302.
PATRIC17890131. VBIRicCon45613_1494.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0326.
HOGENOMHOG000031989.
KOK04079.
OMALTDSPAC.
OrthoDBEOG65TRNM.
ProtClustDBPRK05218.

Family and domain databases

Gene3D3.30.565.10. 1 hit.
HAMAPMF_00505. HSP90.
InterProIPR003594. HATPase_ATP-bd.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR027058. HtpG.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERPTHR11528. PTHR11528. 1 hit.
PTHR11528:SF39. PTHR11528:SF39. 1 hit.
PfamPF00183. HSP90. 1 hit.
[Graphical view]
PIRSFPIRSF002583. Hsp90. 1 hit.
PRINTSPR00775. HEATSHOCK90.
SMARTSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEPS00298. HSP90. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHTPG_RICCN
AccessionPrimary (citable) accession number: P58478
Entry history
Integrated into UniProtKB/Swiss-Prot: December 13, 2001
Last sequence update: December 13, 2001
Last modified: February 19, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia conorii

(strain Malish 7): entries and gene names