Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Kinin-like peptide-S

Gene
N/A
Organism
Lycosa erythrognatha (Spider) (Scaptocosa raptoria)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Has kinin-like biological properties. Causes contraction of isolated guinea pig ileum and relaxation of rat duodenum. Has a number of hypotensive properties: decreases arterial blood pressure and increases capillary permeability. Induces edema when injected into hindpaw of rat. May target bradykinin receptors (BDKRB). Does not lyse unfibrinolysed blood.1 Publication

Miscellaneous

The molecular weight of about 4 kDa suggests that the mature peptide comprises about 36 amino acid residues.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionBradykinin receptor impairing toxin, G-protein coupled receptor impairing toxin, Toxin, Vasoactive, Vasodilator

Names & Taxonomyi

Protein namesi
Recommended name:
Kinin-like peptide-S
OrganismiLycosa erythrognatha (Spider) (Scaptocosa raptoria)
Taxonomic identifieri332789 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAraneaeAraneomorphaeEntelegynaeLycosoideaLycosidaeLycosa

Organism-specific databases

ArachnoServeriAS000005. Kinin-1-Lycosa erythognatha.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000843091 – ›14Kinin-like peptide-SAdd BLAST›14

Expressioni

Tissue specificityi

Expressed by the venom gland.

Family & Domainsi

Sequence similaritiesi

Belongs to the bradykinin-related peptide family.Curated

Sequencei

Sequence statusi: Fragment.

Length:14
Mass (Da):1,511
Last modified:December 13, 2001 - v1
Checksum:iE811E2E5D2EE27CA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei141

Similar proteinsi

Entry informationi

Entry nameiKLPS_LYCER
AccessioniPrimary (citable) accession number: P58396
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 13, 2001
Last sequence update: December 13, 2001
Last modified: November 22, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families