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P58380

- FABI1_RHIME

UniProt

P58380 - FABI1_RHIME

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Protein

Enoyl-[acyl-carrier-protein] reductase [NADH] 1

Gene
fabI1, R00898, SMc00005
Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

An acyl-[acyl-carrier protein] + NAD+ = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei17 – 171NAD; via carbonyl oxygen By similarity
Binding sitei44 – 441NAD By similarity
Binding sitei96 – 961NAD; via carbonyl oxygen By similarity
Active sitei149 – 1491Proton acceptor By similarity
Active sitei159 – 1591Proton acceptor By similarity
Binding sitei166 – 1661NAD By similarity
Sitei207 – 2071Involved in acyl-ACP binding By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi23 – 242NAD By similarity
Nucleotide bindingi68 – 692NAD By similarity
Nucleotide bindingi195 – 1995NAD By similarity

GO - Molecular functioni

  1. enoyl-[acyl-carrier-protein] reductase (NADH) activity Source: UniProtKB-EC

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-113-MONOMER.
RETL1328306-WGS:GSTH-954-MONOMER.
SMEL266834:GJF6-918-MONOMER.
UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] 1 (EC:1.3.1.9)
Alternative name(s):
NADH-dependent enoyl-ACP reductase 1
Gene namesi
Name:fabI1
Ordered Locus Names:R00898
ORF Names:SMc00005
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001976: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 272272Enoyl-[acyl-carrier-protein] reductase [NADH] 1PRO_0000054905Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266834.SMc00005.

Structurei

3D structure databases

ProteinModelPortaliP58380.
SMRiP58380. Positions 6-266.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0623.
KOiK00208.
OMAiTGEIHHV.
OrthoDBiEOG6HF644.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR014358. Enoyl-ACP_Rdtase_NADH.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PIRSFiPIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTSiPR00081. GDHRDH.

Sequencei

Sequence statusi: Complete.

P58380-1 [UniParc]FASTAAdd to Basket

« Hide

MAQASGLMNG KRGVIMGVAN NRSIAWGIAK ALAEAGAEIA LTWQGDALKK    50
RVEPLAQELG AFMAGHCDVT DLATIDAVFS ALEEKWGKID FVVHAIAFSD 100
KDELTGRYLD TSRDNFARTM DISVYSFTAV AARADRVMND GGSILTLTYY 150
GAEKVMPHYN VMGVAKAALE ASVRYLAVDL GNRGIRVNAI SAGPIKTLAA 200
SGIGDFRYIL KWNEYNAPLK RTVSIEEVGN SALYLLSDLS SGVTGEVHHV 250
DSGYHTVGMK AVDAPDISVL KD 272
Length:272
Mass (Da):29,148
Last modified:November 16, 2001 - v1
Checksum:i1E0FA18A22CDBE36
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL591688 Genomic DNA. Translation: CAC45470.1.
RefSeqiNP_385004.1. NC_003047.1.

Genome annotation databases

EnsemblBacteriaiCAC45470; CAC45470; SMc00005.
GeneIDi1232539.
KEGGisme:SMc00005.
PATRICi23631061. VBISinMel96828_2294.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL591688 Genomic DNA. Translation: CAC45470.1 .
RefSeqi NP_385004.1. NC_003047.1.

3D structure databases

ProteinModelPortali P58380.
SMRi P58380. Positions 6-266.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266834.SMc00005.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC45470 ; CAC45470 ; SMc00005 .
GeneIDi 1232539.
KEGGi sme:SMc00005.
PATRICi 23631061. VBISinMel96828_2294.

Phylogenomic databases

eggNOGi COG0623.
KOi K00208.
OMAi TGEIHHV.
OrthoDBi EOG6HF644.

Enzyme and pathway databases

UniPathwayi UPA00094 .
BioCyci RETL1328306-WGS:GSTH-113-MONOMER.
RETL1328306-WGS:GSTH-954-MONOMER.
SMEL266834:GJF6-918-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR014358. Enoyl-ACP_Rdtase_NADH.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PIRSFi PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTSi PR00081. GDHRDH.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.

Entry informationi

Entry nameiFABI1_RHIME
AccessioniPrimary (citable) accession number: P58380
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: November 16, 2001
Last modified: July 9, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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