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P58284 (MTA1_AZOBR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Modification methylase AbrI

Short name=M.AbrI
EC=2.1.1.72
Alternative name(s):
Adenine-specific methyltransferase AbrI
Gene names
Name:abrIM
OrganismAzospirillum brasilense
Taxonomic identifier192 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeAzospirillum

Protein attributes

Sequence length140 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Function

This methylase recognizes the double-stranded sequence CTCGAG, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the AbrI endonuclease Potential.

Catalytic activity

S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

Sequence similarities

Belongs to the N(4)/N(6)-methyltransferase family.

Ontologies

Keywords
   Biological processRestriction system
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
Gene Ontology (GO)
   Biological_processDNA restriction-modification system

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionsite-specific DNA-methyltransferase (adenine-specific) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 140›140Modification methylase AbrI
PRO_0000087942

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
P58284 [UniParc].

Last modified September 26, 2001. Version 1.
Checksum: 7B5BC7D96697E174

FASTA14015,900
        10         20         30         40         50         60 
YRTIDRIYPA LTREHKLLIP DIKGEAHIVY EEGRLYPHHN LYYITSEIWD LRALQAVLLS 

        70         80         90        100        110        120 
GIARLFVSVY STKMHGGFLR FQAQYLRRIR VPNWSQVPAA VRQELITAGA KPDLAACNRA 

       130        140 
VFALYAMTAE ERAALGGNGD 

« Hide

References

[1]"AbrI restriction modification system from Azospirillium brasilense, molecular cloning and characterization of its genes."
Schwabe G., Helke A., Klingmueller W.
Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 29711 / DSM 1844.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X62690 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalP58284.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

REBASE4924. M.AbrI.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameMTA1_AZOBR
AccessionPrimary (citable) accession number: P58284
Entry history
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: September 26, 2001
Last modified: April 16, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Restriction enzymes and methylases

Classification of restriction enzymes and methylases and list of entries