P58255 (PTB_CLOAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphate butyryltransferase
EC=2.3.1.19

Alternative name(s):
Phosphotransbutyrylase

Gene names

Name:	ptb
Ordered Locus Names:	CA_C3076

Organism

Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) [Reference proteome] [HAMAP]

Taxonomic identifier

272562 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › Clostridium acetobutylicum

Protein attributes

Sequence length	301 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate By similarity.
Catalytic activity	Butanoyl-CoA + phosphate = CoA + butanoylphosphate.
Pathway	Lipid metabolism; butanoate metabolism.
Sequence similarities	Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	butyrate metabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	phosphate butyryltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 301	301	Phosphate butyryltransferase		PRO_0000179152

Sequences

	Sequence		Length	Mass (Da)
	P58255 [UniParc]. Last modified August 29, 2001. Version 1. Checksum: B92A01C4E5EA7F73	FASTA	301	32,228
	10 20 30 40 50 60 MIKSFNEIIM KVKSKEMKKV AVAVAQDEPV LEAVRDAKKN GIADAILVGD HDEIVSIALK 70 80 90 100 110 120 IGMDVNDFEI VNEPNVKKAA LKAVELVSTG KADMVMKGLV NTATFLRSVL NKEVGLRTGK 130 140 150 160 170 180 TMSHVAVFET EKFDRLLFLT DVAFNTYPEL KEKIDIVNNS VKVAHAIGIE NPKVAPICAV 190 200 210 220 230 240 EVINPKMPST LDAAMLSKMS DRGQIKGCVV DGPLALDIAL SEEAAHHKGV TGEVAGKADI 250 260 270 280 290 300 FLMPNIETGN VMYKTLTYTT DSKNGGILVG TSAPVVLTSR ADSHETKMNS IALAALVAGN K

References

[1]

"Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum." Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V., Smith D.R. J. Bacteriol. 183:4823-4838(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001437 Genomic DNA. Translation: AAK81016.1.
PIR	E97278.
RefSeq	NP_349676.1. NC_003030.1.
3D structure databases
ProteinModelPortal	P58255.
ModBase	Search...
Protein-protein interaction databases
STRING	272562.CA_C3076.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK81016; AAK81016; CA_C3076.
GeneID	1119259.
KEGG	cac:CA_C3076.
PATRIC	32040561. VBICloAce74127_3259.
Phylogenomic databases
eggNOG	COG0280.
HOGENOM	HOG000009438.
KO	K00634.
OMA	FEVPNYD.
ProtClustDB	PRK05805.
Enzyme and pathway databases
BioCyc	CACE272562:GJIH-3159-MONOMER. MetaCyc:PTBCLOS-MONOMER.
SABIO-RK	P58255.
UniPathway	UPA00863.
Family and domain databases
InterPro	IPR012147. P_Ac_Bu_trans. IPR014079. Phosphate_butyryltransferase. IPR002505. PTA_PTB. [Graphical view]
Pfam	PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMs	TIGR02706. P_butyryltrans. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTB_CLOAB

Accession

Primary (citable) accession number: P58255

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 29, 2001
Last sequence update:	August 29, 2001
Last modified:	May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program