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P58192 (RPOA2_SULSO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit A''

EC=2.7.7.6
Gene names
Name:rpoA2
Ordered Locus Names:SSO0223
OrganismSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) [Reference proteome] [HAMAP]
Taxonomic identifier273057 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length392 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP-Rule MF_00411

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_00411

Subunit structure

This RNA polymerase is composed of 13 subunits By similarity.

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Sequence caution

The sequence AAK40565.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   Molecular functionNucleotidyltransferase
Transferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-templated

Inferred from electronic annotation. Source: InterPro

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: InterPro

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 392392DNA-directed RNA polymerase subunit A'' HAMAP-Rule MF_00411
PRO_0000074026

Secondary structure

.................................................................................. 392
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P58192 [UniParc].

Last modified June 20, 2001. Version 1.
Checksum: 5B0E871D056CE08B

FASTA39243,488
        10         20         30         40         50         60 
MIDEKDKPYL EEKVKQASNI LPQKIVDDLK NLILNKEIIV TRDEIDKIFD LAIKEYSEGL 

        70         80         90        100        110        120 
IAPGEAIGIV AAQSVGEPGT QMTLRTFHFA GIRELNVTLG LPRLIEIVDA KKVPSTPMMT 

       130        140        150        160        170        180 
IYLTDEYKRD RDKALEVARK LEYTKIENVV SSTSIDIASM SIILQLDNEM LKDKGVTVDD 

       190        200        210        220        230        240 
VKKAIGRLKL GDFMIEESED STLNINFANI DSIAALFKLR DKILNTKIKG IKGIKRAIVQ 

       250        260        270        280        290        300 
KKGDEYIILT DGSNLSGVLS VKGVDVAKVE TNNIREIEEV FGIEAAREII IREISKVLAE 

       310        320        330        340        350        360 
QGLDVDIRHI LLIADVMTRT GIVRQIGRHG VTGEKNSVLA RAAFEVTVKH LLDAAARGDV 

       370        380        390 
EEFKGVVENI IIGHPIKLGT GMVELTMRPI LR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006641 Genomic DNA. Translation: AAK40565.1. Different initiation.
PIRF90163.
RefSeqNP_341775.1. NC_002754.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2PMZX-ray3.40C/G1-392[»]
3HKZX-ray3.40C/M1-392[»]
ProteinModelPortalP58192.
SMRP58192. Positions 8-392.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-60639N.
STRING273057.SSO0223.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK40565; AAK40565; SSO0223.
GeneID1455375.
KEGGsso:SSO0223.

Phylogenomic databases

eggNOGCOG0086.
HOGENOMHOG000222986.
KOK03042.
OMARPIGRHG.

Enzyme and pathway databases

BioCycSSOL273057:GCH2-212-MONOMER.

Family and domain databases

HAMAPMF_00411. RNApol_arch_A.
InterProIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsTIGR02389. RNA_pol_rpoA2. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP58192.

Entry information

Entry nameRPOA2_SULSO
AccessionPrimary (citable) accession number: P58192
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: June 20, 2001
Last modified: May 14, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references