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Protein

TATA-box-binding protein

Gene

tbp

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSSOL273057:GCH2-902-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
TATA-box-binding protein
Alternative name(s):
Box A-binding protein
Short name:
BAP
TATA sequence-binding protein
Short name:
TBP
TATA-box factor
Gene namesi
Name:tbp
Synonyms:tfiID
Ordered Locus Names:SSO0951
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001974 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198TATA-box-binding proteinPRO_0000154026Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273057.SSO0951.

Structurei

3D structure databases

ProteinModelPortaliP58178.
SMRiP58178. Positions 6-194.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati14 – 90771Add
BLAST
Repeati105 – 181772Add
BLAST

Sequence similaritiesi

Belongs to the TBP family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
HOGENOMiHOG000105163.
InParanoidiP58178.
KOiK03120.
OMAiMDCLEAI.

Family and domain databases

Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P58178-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNSAVSYKP IVNIENIVAT VTLEQSLDLY AMERSIPNIE YDPDQFPGLI
60 70 80 90 100
FRLEQPKVTA LIFKSGKMVV TGAKSTEELI KAVKRIIKTL KKYGIKIVGK
110 120 130 140 150
PKIQIQNIVA SANLHVNVNL DKAAFLLENN MYEPEQFPGL IFRMDDPRVV
160 170 180 190
LLIFSSGKMV ITGAKREDEV SKAVKRIFDK LAELDCVKPI EEEEELEL
Length:198
Mass (Da):22,309
Last modified:June 20, 2001 - v1
Checksum:i231448D0B2B026D7
GO

Sequence cautioni

The sequence AAK41225.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK41225.1. Different initiation.
PIRiB90246.

Genome annotation databases

EnsemblBacteriaiAAK41225; AAK41225; SSO0951.
KEGGisso:SSO0951.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK41225.1. Different initiation.
PIRiB90246.

3D structure databases

ProteinModelPortaliP58178.
SMRiP58178. Positions 6-194.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273057.SSO0951.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK41225; AAK41225; SSO0951.
KEGGisso:SSO0951.

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
HOGENOMiHOG000105163.
InParanoidiP58178.
KOiK03120.
OMAiMDCLEAI.

Enzyme and pathway databases

BioCyciSSOL273057:GCH2-902-MONOMER.

Family and domain databases

Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

Entry informationi

Entry nameiTBP_SULSO
AccessioniPrimary (citable) accession number: P58178
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: June 20, 2001
Last modified: May 11, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.