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Protein

28S ribosomal protein S6, mitochondrial

Gene

Mrps6

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • small ribosomal subunit rRNA binding Source: GO_Central
  • structural constituent of ribosome Source: UniProtKB

GO - Biological processi

  • mitochondrial translation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S6, mitochondrial
Short name:
MRP-S6
Short name:
S6mt
Gene namesi
Name:Mrps6
Synonyms:Rpms6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2153111. Mrps6.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial small ribosomal subunit Source: UniProtKB
  • mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001768932 – 12528S ribosomal protein S6, mitochondrialAdd BLAST124

Proteomic databases

EPDiP58064.
PaxDbiP58064.
PeptideAtlasiP58064.
PRIDEiP58064.

PTM databases

iPTMnetiP58064.
PhosphoSitePlusiP58064.

Expressioni

Gene expression databases

BgeeiENSMUSG00000039680.
ExpressionAtlasiP58064. baseline and differential.
GenevisibleiP58064. MM.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037631.

Structurei

3D structure databases

ProteinModelPortaliP58064.
SMRiP58064.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S6P family.Curated

Phylogenomic databases

eggNOGiKOG4708. Eukaryota.
COG0360. LUCA.
GeneTreeiENSGT00390000014606.
HOGENOMiHOG000045806.
HOVERGENiHBG082699.
InParanoidiP58064.
KOiK02990.
OMAiQPCTLHE.
OrthoDBiEOG091G0W0U.
PhylomeDBiP58064.
TreeFamiTF314045.

Family and domain databases

Gene3Di3.30.70.60. 1 hit.
InterProiIPR000529. Ribosomal_S6.
IPR014717. Transl_elong_EF1B/ribosomal_S6.
[Graphical view]
PfamiPF01250. Ribosomal_S6. 1 hit.
[Graphical view]
SUPFAMiSSF54995. SSF54995. 1 hit.
TIGRFAMsiTIGR00166. S6. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P58064-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRYELALIL KAMRRPETAA ALKRTIESLM DRGAIVRNLE SLGERALPYR
60 70 80 90 100
ISSHSQQHSR GGYFLVDFYA PTSAVENILE HLARDIDVVR PNIVKHPLTQ
110 120
EVKECDGIVP VPLEEKLYST KRRKK
Length:125
Mass (Da):14,309
Last modified:January 23, 2007 - v3
Checksum:i8140DB0DBFDD9025
GO

Sequence cautioni

The sequence BAB40996 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049943 mRNA. Translation: BAB40996.1. Different initiation.
AY061856 mRNA. Translation: AAL35740.1.
BC027271 mRNA. Translation: AAH27271.1.
CCDSiCCDS28332.1.
RefSeqiNP_536704.1. NM_080456.1.
UniGeneiMm.217354.

Genome annotation databases

EnsembliENSMUST00000047429; ENSMUSP00000037631; ENSMUSG00000039680.
GeneIDi121022.
KEGGimmu:121022.
UCSCiuc007zyu.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049943 mRNA. Translation: BAB40996.1. Different initiation.
AY061856 mRNA. Translation: AAL35740.1.
BC027271 mRNA. Translation: AAH27271.1.
CCDSiCCDS28332.1.
RefSeqiNP_536704.1. NM_080456.1.
UniGeneiMm.217354.

3D structure databases

ProteinModelPortaliP58064.
SMRiP58064.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037631.

PTM databases

iPTMnetiP58064.
PhosphoSitePlusiP58064.

Proteomic databases

EPDiP58064.
PaxDbiP58064.
PeptideAtlasiP58064.
PRIDEiP58064.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000047429; ENSMUSP00000037631; ENSMUSG00000039680.
GeneIDi121022.
KEGGimmu:121022.
UCSCiuc007zyu.1. mouse.

Organism-specific databases

CTDi64968.
MGIiMGI:2153111. Mrps6.

Phylogenomic databases

eggNOGiKOG4708. Eukaryota.
COG0360. LUCA.
GeneTreeiENSGT00390000014606.
HOGENOMiHOG000045806.
HOVERGENiHBG082699.
InParanoidiP58064.
KOiK02990.
OMAiQPCTLHE.
OrthoDBiEOG091G0W0U.
PhylomeDBiP58064.
TreeFamiTF314045.

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Miscellaneous databases

PROiP58064.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000039680.
ExpressionAtlasiP58064. baseline and differential.
GenevisibleiP58064. MM.

Family and domain databases

Gene3Di3.30.70.60. 1 hit.
InterProiIPR000529. Ribosomal_S6.
IPR014717. Transl_elong_EF1B/ribosomal_S6.
[Graphical view]
PfamiPF01250. Ribosomal_S6. 1 hit.
[Graphical view]
SUPFAMiSSF54995. SSF54995. 1 hit.
TIGRFAMsiTIGR00166. S6. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRT06_MOUSE
AccessioniPrimary (citable) accession number: P58064
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 120 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.