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Protein

28S ribosomal protein S6, mitochondrial

Gene

Mrps6

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • small ribosomal subunit rRNA binding Source: GO_Central
  • structural constituent of ribosome Source: UniProtKB

GO - Biological processi

  • mitochondrial translation Source: UniProtKB

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S6, mitochondrial
Short name:
MRP-S6
Short name:
S6mt
Gene namesi
Name:Mrps6
Synonyms:Rpms6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2153111. Mrps6.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001768931 – 12528S ribosomal protein S6, mitochondrialAdd BLAST125

Proteomic databases

EPDiP58064.
PaxDbiP58064.
PeptideAtlasiP58064.
PRIDEiP58064.

PTM databases

iPTMnetiP58064.
PhosphoSitePlusiP58064.

Expressioni

Gene expression databases

BgeeiENSMUSG00000039680.
ExpressionAtlasiP58064. baseline and differential.
GenevisibleiP58064. MM.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037631.

Structurei

3D structure databases

ProteinModelPortaliP58064.
SMRiP58064.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4708. Eukaryota.
COG0360. LUCA.
GeneTreeiENSGT00390000014606.
HOGENOMiHOG000045806.
HOVERGENiHBG082699.
InParanoidiP58064.
KOiK02990.
OMAiPKSYPIA.
OrthoDBiEOG091G0W0U.
PhylomeDBiP58064.
TreeFamiTF314045.

Family and domain databases

Gene3Di3.30.70.60. 1 hit.
InterProiView protein in InterPro
IPR000529. Ribosomal_S6.
IPR035980. Ribosomal_S6_sf.
IPR014717. Transl_elong_EF1B/ribosomal_S6.
PANTHERiPTHR21011. PTHR21011. 1 hit.
PfamiView protein in Pfam
PF01250. Ribosomal_S6. 1 hit.
SUPFAMiSSF54995. SSF54995. 1 hit.
TIGRFAMsiTIGR00166. S6. 1 hit.

Sequencei

Sequence statusi: Complete.

P58064-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRYELALIL KAMRRPETAA ALKRTIESLM DRGAIVRNLE SLGERALPYR
60 70 80 90 100
ISSHSQQHSR GGYFLVDFYA PTSAVENILE HLARDIDVVR PNIVKHPLTQ
110 120
EVKECDGIVP VPLEEKLYST KRRKK
Length:125
Mass (Da):14,309
Last modified:January 23, 2007 - v3
Checksum:i8140DB0DBFDD9025
GO

Sequence cautioni

The sequence BAB40996 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049943 mRNA. Translation: BAB40996.1. Different initiation.
AY061856 mRNA. Translation: AAL35740.1.
BC027271 mRNA. Translation: AAH27271.1.
CCDSiCCDS28332.1.
RefSeqiNP_536704.1. NM_080456.1.
UniGeneiMm.217354.

Genome annotation databases

EnsembliENSMUST00000047429; ENSMUSP00000037631; ENSMUSG00000039680.
GeneIDi121022.
KEGGimmu:121022.
UCSCiuc007zyu.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiRT06_MOUSE
AccessioniPrimary (citable) accession number: P58064
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: January 23, 2007
Last modified: October 25, 2017
This is version 127 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families