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P58063 (TRUB_CAUCR) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase B

EC=5.4.99.25
Alternative name(s):
tRNA pseudouridine(55) synthase
Short name=Psi55 synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene names
Name:truB
Ordered Locus Names:CC_0036
OrganismCaulobacter crescentus (strain ATCC 19089 / CB15) [Reference proteome] [HAMAP]
Taxonomic identifier190650 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity. HAMAP-Rule MF_01080

Catalytic activity

tRNA uridine55 = tRNA pseudouridine55. HAMAP-Rule MF_01080

Sequence similarities

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA pseudouridine synthesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 310310tRNA pseudouridine synthase B HAMAP-Rule MF_01080
PRO_0000121814

Sites

Active site471Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
P58063 [UniParc].

Last modified May 4, 2001. Version 1.
Checksum: 42491C54EFF328FE

FASTA31033,596
        10         20         30         40         50         60 
MARRKKGDAV SGWLCLDKPY DLTSTTAVSR VRRAFNAQKG GHAGTLDPLA TGILPIALGE 

        70         80         90        100        110        120 
ATKTVPFLMD ADKAYRFTIA WGRDTTTLDR EGETTGTSDV RPTREQVEAA LPAFIGEVDQ 

       130        140        150        160        170        180 
IPPNFSAIKV DGERAYDLAR DGVEFELPTR KVSIFDLKVV DQPDADHVTL TMECGKGTYV 

       190        200        210        220        230        240 
RAVVRDLAKA LGTCGHVADL RRTRVGGFSE ASAIALETLE NLSYEARLSE ALLPVETALD 

       250        260        270        280        290        300 
DIPALAVTDE DAFRLAQGRA IVLLPRQVET LKAELPPGDR TVSAMSGDRL VALCEMRAGK 

       310 
LNPVRVFQLT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005673 Genomic DNA. Translation: AAK22024.1.
PIRD87253.
RefSeqNP_418856.1. NC_002696.2.

3D structure databases

ProteinModelPortalP58063.
SMRP58063. Positions 9-307.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK22024; AAK22024; CC_0036.
GeneID944095.
KEGGccr:CC_0036.
PATRIC21296992. VBICauCre124313_0036.

Phylogenomic databases

eggNOGCOG0130.
HOGENOMHOG000231225.
KOK03177.
OMAQKVKRIF.
OrthoDBEOG6358D3.
ProtClustDBPRK05389.

Enzyme and pathway databases

BioCycCAULO:CC0036-MONOMER.

Family and domain databases

HAMAPMF_01080. TruB_bact.
InterProIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERPTHR13767. PTHR13767. 1 hit.
PfamPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMSSF55120. SSF55120. 1 hit.
TIGRFAMsTIGR00431. TruB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRUB_CAUCR
AccessionPrimary (citable) accession number: P58063
Entry history
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: May 4, 2001
Last modified: March 19, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families