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Protein

Insertion element IS1 4 protein InsB

Gene

insB4

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Absolutely required for transposition of IS1.

GO - Molecular functioni

GO - Biological processi

  • transposition, DNA-mediated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

DNA recombination, Transposition

Enzyme and pathway databases

BioCyciEcoCyc:G6509-MONOMER.
ECOL316407:JW0972-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Insertion element IS1 4 protein InsB
Alternative name(s):
IS1d
Gene namesi
Name:insB4
Ordered Locus Names:b0988, JW0972
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG40002. insB4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 167167Insertion element IS1 4 protein InsBPRO_0000075403Add
BLAST

Proteomic databases

PaxDbiP57998.

Interactioni

Protein-protein interaction databases

IntActiP57998. 2 interactions.
STRINGi511145.b0988.

Structurei

3D structure databases

ProteinModelPortaliP57998.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transposase 27 family.Curated

Phylogenomic databases

eggNOGiCOG1662. LUCA.
HOGENOMiHOG000036821.
InParanoidiP57998.
KOiK07480.
OMAiRASAGWF.
OrthoDBiEOG6Q2SKW.
PhylomeDBiP57998.

Family and domain databases

InterProiIPR005063. Transposase_27.
[Graphical view]
PfamiPF03400. DDE_Tnp_IS1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57998-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGNSPHYGR WPQHDFPPFK KLRPQSVTSR IQPGSDVIVC AEMDEQWGYV
60 70 80 90 100
GAKSRQRWLF YAYDRLRKTV VAHVFGERTM ATLGRLMSLL SPFDVVIWMT
110 120 130 140 150
DGWPLYESRL KGKLHVISKR YTQRIERYNL NLRQHLARLG RKSLSFSKSV
160
ELHDKVIGHY LNIKHYQ
Length:167
Mass (Da):19,700
Last modified:April 27, 2001 - v1
Checksum:i9FBF4EAF6BFA89D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52536 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC74073.1.
AP009048 Genomic DNA. Translation: BAA35754.1.
RefSeqiNP_415508.1. NC_000913.3.
WP_001119339.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74073; AAC74073; b0988.
BAA35754; BAA35754; BAA35754.
GeneIDi945009.
KEGGiecj:JW0972.
eco:b0988.
PATRICi32117201. VBIEscCol129921_1024.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52536 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC74073.1.
AP009048 Genomic DNA. Translation: BAA35754.1.
RefSeqiNP_415508.1. NC_000913.3.
WP_001119339.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP57998.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP57998. 2 interactions.
STRINGi511145.b0988.

Proteomic databases

PaxDbiP57998.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74073; AAC74073; b0988.
BAA35754; BAA35754; BAA35754.
GeneIDi945009.
KEGGiecj:JW0972.
eco:b0988.
PATRICi32117201. VBIEscCol129921_1024.

Organism-specific databases

EchoBASEiEB4719.
EcoGeneiEG40002. insB4.

Phylogenomic databases

eggNOGiCOG1662. LUCA.
HOGENOMiHOG000036821.
InParanoidiP57998.
KOiK07480.
OMAiRASAGWF.
OrthoDBiEOG6Q2SKW.
PhylomeDBiP57998.

Enzyme and pathway databases

BioCyciEcoCyc:G6509-MONOMER.
ECOL316407:JW0972-MONOMER.

Miscellaneous databases

PROiP57998.

Family and domain databases

InterProiIPR005063. Transposase_27.
[Graphical view]
PfamiPF03400. DDE_Tnp_IS1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Four types of IS1 with differences in nucleotide sequence reside in the Escherichia coli K-12 chromosome."
    Umeda M., Ohtsubo E.
    Gene 98:1-5(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiINSB4_ECOLI
AccessioniPrimary (citable) accession number: P57998
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: November 11, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome, Transposable element

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.