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P57973

- PGK_PASMU

UniProt

P57973 - PGK_PASMU

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Pasteurella multocida (strain Pm70)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361SubstrateBy similarity
Binding sitei113 – 1131SubstrateBy similarity
Binding sitei146 – 1461SubstrateBy similarity
Binding sitei197 – 1971ATPBy similarity
Binding sitei314 – 3141ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi340 – 3434ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMUL272843:GC8W-1935-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:PM1860
OrganismiPasteurella multocida (strain Pm70)
Taxonomic identifieri272843 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaePasteurella
ProteomesiUP000000809: Chromosome

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 387387Phosphoglycerate kinasePRO_0000145980Add
BLAST

Proteomic databases

PRIDEiP57973.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi272843.PM1860.

Structurei

3D structure databases

ProteinModelPortaliP57973.
SMRiP57973. Positions 2-385.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate bindingBy similarity
Regioni59 – 624Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57973-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVIKMTDLD LSGKRVFIRA DLNVPVKDGK VTSDARIRAT IPTLKLALEK
60 70 80 90 100
GAKVMVTSHL GRPTEGEFDE ANSLKPVVDY LNANLDVPVR LVRDYLDGVD
110 120 130 140 150
VNQGEIVVLE NVRINKGEKK NDPELGKKYA ALCDVFVMDA FGTAHRAQAS
160 170 180 190 200
TYGVAEYAPV ACAGPLLAAE LDALGKALKE PARPMVAIVG GSKVSTKLEV
210 220 230 240 250
LNSLSKIADQ IIVGGGIANT FIAAAGHNVG KSLYEEDLIP VAKNLAASTD
260 270 280 290 300
IPVPVDVRVG LEFSETAAAT EKAVNEVKDD ESIFDIGDKS AEQLAEIIKN
310 320 330 340 350
AKTILWNGPV GVFEFPNFRK GTEIISHAIA NSEGFSIAGG GDTLAAIDLF
360 370 380
GIKDKISYIS TGGGAFLEFV EGKVLPAVEI LEKRANG
Length:387
Mass (Da):41,030
Last modified:April 27, 2001 - v1
Checksum:i06F96C85EE019735
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004439 Genomic DNA. Translation: AAK03944.1.
RefSeqiNP_246799.1. NC_002663.1.

Genome annotation databases

EnsemblBacteriaiAAK03944; AAK03944; PM1860.
GeneIDi1245207.
KEGGipmu:PM1860.
PATRICi22873043. VBIPasMul88067_1882.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004439 Genomic DNA. Translation: AAK03944.1 .
RefSeqi NP_246799.1. NC_002663.1.

3D structure databases

ProteinModelPortali P57973.
SMRi P57973. Positions 2-385.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272843.PM1860.

Proteomic databases

PRIDEi P57973.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK03944 ; AAK03944 ; PM1860 .
GeneIDi 1245207.
KEGGi pmu:PM1860.
PATRICi 22873043. VBIPasMul88067_1882.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci PMUL272843:GC8W-1935-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pm70.

Entry informationi

Entry nameiPGK_PASMU
AccessioniPrimary (citable) accession number: P57973
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: October 29, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3