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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Pasteurella multocida (strain Pm70)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.By similarity

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC:3.6.1.41)
Alternative name(s):
Ap4A hydrolase
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase
Diadenosine tetraphosphatase
Gene namesi
Name:apaH
Ordered Locus Names:PM1210
OrganismiPasteurella multocida (strain Pm70)
Taxonomic identifieri272843 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaePasteurella
Proteomesi
  • UP000000809 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001980011 – 275Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST275

Interactioni

Protein-protein interaction databases

STRINGi272843.PM1210

Structurei

3D structure databases

ProteinModelPortaliP57922
SMRiP57922
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.Curated

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

P57922-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYLVGDLQ GCYDELQRLL EKVQFDSTQD QLYLVGDLVA RGDKSLECLR
60 70 80 90 100
FVKSLGKSAK TVLGNHDLHL ISTALGIKKV KVRDRVDAIF HAPDFEELID
110 120 130 140 150
WLRHQPLLVH NEQQNFLMTH AGISPDWDLA TAKQCAHEVE NVLRHGDYHN
160 170 180 190 200
LIENMYENRP DRWHDDLQGL DRLRYSINVF TRMRFCYWDH RLDFDCKLPP
210 220 230 240 250
ESAPEELTPW FNLANPLYQT IPIVFGHWAS LVNTTTPNNI YALDTGCVWG
260 270
NRMTMLRWED KQYFSQHAVK NYRDF
Length:275
Mass (Da):32,225
Last modified:April 27, 2001 - v1
Checksum:iF31422F7C61D6D84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004439 Genomic DNA Translation: AAK03294.1
RefSeqiWP_005751893.1, NC_002663.1

Genome annotation databases

EnsemblBacteriaiAAK03294; AAK03294; PM1210
KEGGipmu:PM1210

Similar proteinsi

Entry informationi

Entry nameiAPAH_PASMU
AccessioniPrimary (citable) accession number: P57922
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: March 28, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health