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P57866 (ACKA_PASMU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:PM0704
OrganismPasteurella multocida (strain Pm70) [Complete proteome] [HAMAP]
Taxonomic identifier272843 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Pasteurella

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Acetate kinase HAMAP MF_00020
PRO_0000107597

Secondary structure

1 ................................................................. 401
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P57866 [UniParc].

Last modified April 27, 2001. Version 1.
Checksum: 7AE1007F77DBA493

FASTA40143,691
        10         20         30         40         50         60 
MSQKLVLILN CGSSSLKFSI LDPQTGEEKL SGLAEAFHLD DARIKWKLHG EKGNADLGAG 

        70         80         90        100        110        120 
AAHSEALNFI VNSIFPLDPS LKEDIVAIGH RIVHGGEKFT SSVVITDEVV QGIKDAVQFA 

       130        140        150        160        170        180 
PLHNPAHLIG IEEAFKMFPH LKDKNVAVFD TAFHQTMPEE AYLYALPYSL YREHGVRRYG 

       190        200        210        220        230        240 
AHGTSHFFVS QQAAERLNVP AEQVNVITCH LGNGASIAAV RHGQCIDTSM GLTPLEGLVM 

       250        260        270        280        290        300 
GTRSGDIDPA IVFYLHDNLG LSVEEINTLL TKKSGLLGLT EVTSDCRYAE DNYDKEASAK 

       310        320        330        340        350        360 
RALDVFSYRL AKYIGSYMAV IGERLDAIVF TGGIGENSSL VRELTLNHLK LFGYQVDSDK 

       370        380        390        400 
NKAARFGHEG VITADNTPVA MVIPTNEELV IAQDTARLCI A

« Hide

References

[1]"Complete genomic sequence of Pasteurella multocida Pm70."
May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed: 11248100] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pm70.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE004439 Genomic DNA. Translation: AAK02788.1.
RefSeqNP_245641.1. NC_002663.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1LP2model-A1-401[»]
ProteinModelPortalP57866.
ModBaseSearch...

Proteomic databases

PRIDEP57866.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1244051.
GenomeReviewsGene locus PM0704 in contig AE004439_GR.
KEGGpmu:PM0704.
NMPDRfig|272843.1.peg.704.
PATRIC22870602. VBIPasMul88067_0712.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG285863.
OMAIVFHLHD.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycPMUL272843:PM0704-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_PASMU
AccessionPrimary (citable) accession number: P57866
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: January 25, 2012
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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