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P57851 (SYR_PASMU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:PM0551
OrganismPasteurella multocida (strain Pm70) [Complete proteome] [HAMAP]
Taxonomic identifier272843 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaePasteurella

Protein attributes

Sequence length563 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 563563Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151586

Regions

Motif108 – 11811"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
P57851 [UniParc].

Last modified April 27, 2001. Version 1.
Checksum: D391474F92DE6DBB

FASTA56363,332
        10         20         30         40         50         60 
MIASGADTQS DALVRQSAKV QFGDYQANGI MAAAKKLGRN PREFAQQVIE QLDLSEIAEK 

        70         80         90        100        110        120 
IEIAGPGFIN LFLDKNWLAE QISLAVNDDK LGIQATETQT VVADYSSPNV AKEMHVGHLR 

       130        140        150        160        170        180 
STIIGDAVVR TLEFLGNKVI RANHVGDWGT QFGMLIAYLE KVENESASEM ELSDLEAFYR 

       190        200        210        220        230        240 
AAKEHYDSDP VFAEKARNYV VKLQSGDEYC RTMWKKLVDI TMQQNQHNYD RLNVTLTEKD 

       250        260        270        280        290        300 
VMGESLYNPM LSDIVADLKQ QGLAVEDEGA FVVYLDEFKN KEGEPMGVIV QKKDGGFLYT 

       310        320        330        340        350        360 
TTDIAAAKYR YETLKADRAL VFSDTRQSQH MQQAWLITRK AGYVPDSFQL EHKNFGMMLG 

       370        380        390        400        410        420 
KDGKPFKTRT GGTVKLADLL DEAVERATQL IQEKSTALSA QEKAAVIEAV AIGSVKYADL 

       430        440        450        460        470        480 
SKNRTTDYVF DWDNMLSFEG NTAPYMQYAY TRIRSIFNRS ELNEQDLSES PVVLSNEKER 

       490        500        510        520        530        540 
LLAIKLLQFE EAIQIVAKEG TPHVLCTYLY ELAGVFSSFY EHCPILNNED EQIKRSRLKL 

       550        560 
ALLTEKTLKQ GLDLLGIKTV DKM 

« Hide

References

[1]"Complete genomic sequence of Pasteurella multocida Pm70."
May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pm70.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004439 Genomic DNA. Translation: AAK02635.1.
RefSeqNP_245488.2. NC_002663.1.

3D structure databases

ProteinModelPortalP57851.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272843.PM0551.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK02635; AAK02635; PM0551.
GeneID1243898.
KEGGpmu:PM0551.
PATRIC22870284. VBIPasMul88067_0558.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycPMUL272843:GC8W-571-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_PASMU
AccessionPrimary (citable) accession number: P57851
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: April 16, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries