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P57847 (SYQ_PASMU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:PM0528
OrganismPasteurella multocida (strain Pm70) [Complete proteome] [HAMAP]
Taxonomic identifier272843 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaePasteurella

Protein attributes

Sequence length559 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 559559Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_0000195841

Regions

Motif44 – 5411"HIGH" region HAMAP-Rule MF_00126
Motif279 – 2835"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2821ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P57847 [UniParc].

Last modified April 27, 2001. Version 1.
Checksum: C3DBC90B65F071D1

FASTA55964,310
        10         20         30         40         50         60 
MSHPVENVVA AENTEKRPTN FIRQIIDEDL ASGKHTGVQT RFPPEPNGYL HIGHAKSICL 

        70         80         90        100        110        120 
NFGIAEDYQG LCNLRFDDTN PVKEDVEYVD SIKQDVEWLG FKWEGEPRYA SDYFDQLYGY 

       130        140        150        160        170        180 
AIELIEKGLA YVDELSPEEM REYRGTLTEP GKNSPYRDRS IEENLALFEK MKNGEIAEGK 

       190        200        210        220        230        240 
ACLRAKIDMA SPFIVMRDPV IYRIKFATHH QTGDKWCIYP MYDFTHCISD AIERITHSLC 

       250        260        270        280        290        300 
TLEFQDNRRL YDWVLENISI ARPLPHQYEF SRLNLESTLT SKRKLLQLVN EGIVDGWNDP 

       310        320        330        340        350        360 
RMPTISGLRR RGYTPASLRE FCRRIGVTKQ DNMVEFSALE ACIREDLNEN APRAMAVINP 

       370        380        390        400        410        420 
LKIVIENFSG KEMLTAPNHP NRDELGVREL PFTRELYIDQ ADFREEANKQ YKRLVLGKEV 

       430        440        450        460        470        480 
RLRNAYVIKA ERVEKDAEEN ITTVYCTYDP DTLGKNPADG RKVKGVIQWV SAEDYLPAEF 

       490        500        510        520        530        540 
RQYGRLFTVA NPGAAEDIHQ VLNPDSLVIK QGVVEKSLAN AQPEKAYQFE REGYYCADSK 

       550 
DSRPDHLVFN LTVSLKEGF 

« Hide

References

[1]"Complete genomic sequence of Pasteurella multocida Pm70."
May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pm70.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004439 Genomic DNA. Translation: AAK02612.1.
RefSeqNP_245465.1. NC_002663.1.

3D structure databases

ProteinModelPortalP57847.
SMRP57847. Positions 19-557.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272843.PM0528.

Proteomic databases

PRIDEP57847.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK02612; AAK02612; PM0528.
GeneID1243875.
KEGGpmu:PM0528.
PATRIC22870236. VBIPasMul88067_0534.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMASREIYID.
OrthoDBEOG6DRPF7.

Enzyme and pathway databases

BioCycPMUL272843:GC8W-548-MONOMER.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_PASMU
AccessionPrimary (citable) accession number: P57847
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: May 14, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries