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P57755 (GLSA_STRCO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:SCO7049
ORF Names:SC4G1.15
OrganismStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [Reference proteome] [HAMAP]
Taxonomic identifier100226 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307Glutaminase HAMAP-Rule MF_00313
PRO_0000110627

Sites

Binding site671Substrate By similarity
Binding site1171Substrate By similarity
Binding site1611Substrate By similarity
Binding site1681Substrate By similarity
Binding site1921Substrate By similarity
Binding site2431Substrate By similarity
Binding site2611Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
P57755 [UniParc].

Last modified January 24, 2001. Version 1.
Checksum: CCF51DFAE88D2079

FASTA30732,556
        10         20         30         40         50         60 
MSTPTTFRPV LERIAEEIER TPGSGRPADY IPALAARDPR RFGMAVAELD GTVYGVGDWR 

        70         80         90        100        110        120 
EPFSAQSLTK VFTLALDLAR EGDALWEHVG REPSGNPFNS LVQLEYENGI PRNPFINAGA 

       130        140        150        160        170        180 
LVVTDRLHTR TGDAAGELLA FLRAESGNPD LGHDEEVAAS EAAHGDRNAA LAHFMASYGN 

       190        200        210        220        230        240 
IDNPVPVLLD QYFRQCSVAA SCADLALATG FLARHGIRAD GTRLLSRSRA KQINAVMLTC 

       250        260        270        280        290        300 
GTYDAAGDFA HRVGLPGKSG VGGGIIAVVP GHCTLCVWGP GLDERGNSVA GVAALDRFTT 


LTGLSVF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL939130 Genomic DNA. Translation: CAC01547.1.
RefSeqNP_631111.1. NC_003888.3.

3D structure databases

ProteinModelPortalP57755.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING100226.SCO7049.

Proteomic databases

PRIDEP57755.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC01547; CAC01547; CAC01547.
GeneID1102487.
KEGGsco:SCO7049.
PATRIC23744021. VBIStrCoe124346_7153.

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMARINALML.
OrthoDBEOG6N94BK.
PhylomeDBP57755.
ProtClustDBPRK00971.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_STRCO
AccessionPrimary (citable) accession number: P57755
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: January 24, 2001
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families