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P57750

- AGM1_ARATH

UniProt

P57750 - AGM1_ARATH

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Protein

Phosphoacetylglucosamine mutase

Gene

DRT101

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Interconverts GlcNAc-6-P and GlcNAc-1-P.By similarity

Catalytic activityi

N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.

Cofactori

Mg2+By similarityNote: Binds 1 Mg(2+) ion per subunit.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei68 – 681Phosphoserine intermediateBy similarity
Metal bindingi68 – 681Magnesium; via phosphate groupBy similarity
Metal bindingi286 – 2861MagnesiumBy similarity
Metal bindingi288 – 2881MagnesiumBy similarity
Metal bindingi290 – 2901MagnesiumBy similarity
Binding sitei527 – 5271SubstrateBy similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoacetylglucosamine mutase activity Source: RefGenome
  3. phosphoglucomutase activity Source: RefGenome

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. glucose 1-phosphate metabolic process Source: RefGenome
  3. photoreactive repair Source: TAIR
  4. response to UV Source: TAIR
  5. UDP-N-acetylglucosamine biosynthetic process Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

DNA damage, DNA repair

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT5G18070-MONOMER.
ReactomeiREACT_190863. Synthesis of UDP-N-acetyl-glucosamine.
UniPathwayiUPA00113; UER00530.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoacetylglucosamine mutase (EC:5.4.2.3)
Short name:
PAGM
Alternative name(s):
Acetylglucosamine phosphomutase
DNA-damage-repair/toleration protein DRT101
N-acetylglucosamine-phosphate mutase
Gene namesi
Name:DRT101
Ordered Locus Names:At5g18070
ORF Names:MRG7.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G18070.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: TAIR
  2. mitochondrion Source: TAIR
  3. plasmodesma Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 556556Phosphoacetylglucosamine mutasePRO_0000148015Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei68 – 681Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP57750.
PRIDEiP57750.

Expressioni

Gene expression databases

GenevestigatoriP57750.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G18070.1-P.

Structurei

3D structure databases

ProteinModelPortaliP57750.
SMRiP57750. Positions 19-554.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni386 – 3883Substrate bindingBy similarity
Regioni518 – 5225Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the phosphohexose mutase family.Curated

Phylogenomic databases

eggNOGiCOG1109.
HOGENOMiHOG000210027.
InParanoidiP57750.
KOiK01836.
OMAiDIVRVYA.
PhylomeDBiP57750.

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 2 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016657. PAGM.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PIRSFiPIRSF016408. PAGM. 1 hit.
SUPFAMiSSF53738. SSF53738. 4 hits.
SSF55957. SSF55957. 1 hit.

Sequencei

Sequence statusi: Complete.

P57750-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDEIQIASIL KSSELFPIPQ GVKLSYGTAG FRGDAKLLES TVYRVGILSA
60 70 80 90 100
LRSLKLGSAT VGLMITASHN KVSDNGIKVS DPSGFMLSQE WEPFADQIAN
110 120 130 140 150
ASSPEELVSL IRKFMEKEEI AIGENNKGAE VWLGRDTRPS GESLLRAGEI
160 170 180 190 200
GVGSILGSVA IDIGILTTPQ LHWMVRAKNK GLKATENDYF ENLSTSFRCL
210 220 230 240 250
IDLIPSSGND KLEISKLLVD GANGVGGQKI EKLRGSLSNL DVEIRNTGRD
260 270 280 290 300
GGVLNEGVGA DFVQKEKVLP VGFGFKDVGM RCASLDGDAD RLVYFYIPSD
310 320 330 340 350
SSEKVELLDG DKILSLFALF IKEQLNALED DEERKQSRLG VVQTAYANGA
360 370 380 390 400
STDYLKHLGL DVVFAKTGVK HLHEKAAEFD IGIYFEANGH GTILFSESFL
410 420 430 440 450
SWLVSKQKDL TAKGQGGSEE HKAVSRLMAV SNLINQAVGD ALSGVLLVEV
460 470 480 490 500
ILQHLGWSIE KWNELYKDLP SRQIKVEVPD RTAVVTTSEE TEALRPMGIQ
510 520 530 540 550
DAINSEIKKY SRGRAFIRPS GTEDVVRVYA EASTQEDADS LANSVAQLVK

SFLGSS
Length:556
Mass (Da):60,391
Last modified:January 24, 2001 - v1
Checksum:iBCADE44F14DDC3D0
GO

Sequence cautioni

The sequence AAA72352.1 differs from that shown. Reason: Sequencing errors.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012246 Genomic DNA. Translation: BAB09465.1.
CP002688 Genomic DNA. Translation: AED92503.1.
AY075620 mRNA. Translation: AAL91631.1.
L11367 mRNA. Translation: AAA72352.1. Sequence problems.
PIRiS35270.
RefSeqiNP_568359.2. NM_121812.2.
UniGeneiAt.466.

Genome annotation databases

EnsemblPlantsiAT5G18070.1; AT5G18070.1; AT5G18070.
GeneIDi831926.
KEGGiath:AT5G18070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012246 Genomic DNA. Translation: BAB09465.1 .
CP002688 Genomic DNA. Translation: AED92503.1 .
AY075620 mRNA. Translation: AAL91631.1 .
L11367 mRNA. Translation: AAA72352.1 . Sequence problems.
PIRi S35270.
RefSeqi NP_568359.2. NM_121812.2.
UniGenei At.466.

3D structure databases

ProteinModelPortali P57750.
SMRi P57750. Positions 19-554.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT5G18070.1-P.

Proteomic databases

PaxDbi P57750.
PRIDEi P57750.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT5G18070.1 ; AT5G18070.1 ; AT5G18070 .
GeneIDi 831926.
KEGGi ath:AT5G18070.

Organism-specific databases

TAIRi AT5G18070.

Phylogenomic databases

eggNOGi COG1109.
HOGENOMi HOG000210027.
InParanoidi P57750.
KOi K01836.
OMAi DIVRVYA.
PhylomeDBi P57750.

Enzyme and pathway databases

UniPathwayi UPA00113 ; UER00530 .
BioCyci ARA:AT5G18070-MONOMER.
Reactomei REACT_190863. Synthesis of UDP-N-acetyl-glucosamine.

Miscellaneous databases

PROi P57750.

Gene expression databases

Genevestigatori P57750.

Family and domain databases

Gene3Di 3.30.310.50. 1 hit.
3.40.120.10. 2 hits.
InterProi IPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016657. PAGM.
[Graphical view ]
Pfami PF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view ]
PIRSFi PIRSF016408. PAGM. 1 hit.
SUPFAMi SSF53738. SSF53738. 4 hits.
SSF55957. SSF55957. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence features of the regions of 1,367,185 bp covered by 19 physically assigned P1 and TAC clones."
    Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N., Tabata S.
    DNA Res. 5:203-216(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Selection of Arabidopsis cDNAs that partially correct phenotypes of Escherichia coli DNA-damage-sensitive mutants and analysis of two plant cDNAs that appear to express UV-specific dark repair activities."
    Pang Q., Hays J.B., Rajagopal I., Schaefer T.S.
    Plant Mol. Biol. 22:411-426(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 183-556.
    Strain: cv. Columbia.
  5. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-68, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Root.

Entry informationi

Entry nameiAGM1_ARATH
AccessioniPrimary (citable) accession number: P57750
Secondary accession number(s): Q05211
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: January 24, 2001
Last modified: November 26, 2014
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3