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P57750 (AGM1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 112. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoacetylglucosamine mutase

Short name=PAGM
EC=5.4.2.3
Alternative name(s):
Acetylglucosamine phosphomutase
DNA-damage-repair/toleration protein DRT101
N-acetylglucosamine-phosphate mutase
Gene names
Name:DRT101
Ordered Locus Names:At5g18070
ORF Names:MRG7.2
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Interconverts GlcNAc-6-P and GlcNAc-1-P By similarity.

Catalytic activity

N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Pathway

Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.

Sequence similarities

Belongs to the phosphohexose mutase family.

Sequence caution

The sequence AAA72352.1 differs from that shown. Reason: Sequencing errors.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 556556Phosphoacetylglucosamine mutase
PRO_0000148015

Sites

Active site681Phosphoserine intermediate By similarity
Metal binding681Magnesium; via phosphate group By similarity
Metal binding2861Magnesium By similarity
Metal binding2881Magnesium By similarity
Metal binding2901Magnesium By similarity

Amino acid modifications

Modified residue681Phosphoserine Ref.5

Sequences

Sequence LengthMass (Da)Tools
P57750 [UniParc].

Last modified January 24, 2001. Version 1.
Checksum: BCADE44F14DDC3D0

FASTA55660,391
        10         20         30         40         50         60 
MDEIQIASIL KSSELFPIPQ GVKLSYGTAG FRGDAKLLES TVYRVGILSA LRSLKLGSAT 

        70         80         90        100        110        120 
VGLMITASHN KVSDNGIKVS DPSGFMLSQE WEPFADQIAN ASSPEELVSL IRKFMEKEEI 

       130        140        150        160        170        180 
AIGENNKGAE VWLGRDTRPS GESLLRAGEI GVGSILGSVA IDIGILTTPQ LHWMVRAKNK 

       190        200        210        220        230        240 
GLKATENDYF ENLSTSFRCL IDLIPSSGND KLEISKLLVD GANGVGGQKI EKLRGSLSNL 

       250        260        270        280        290        300 
DVEIRNTGRD GGVLNEGVGA DFVQKEKVLP VGFGFKDVGM RCASLDGDAD RLVYFYIPSD 

       310        320        330        340        350        360 
SSEKVELLDG DKILSLFALF IKEQLNALED DEERKQSRLG VVQTAYANGA STDYLKHLGL 

       370        380        390        400        410        420 
DVVFAKTGVK HLHEKAAEFD IGIYFEANGH GTILFSESFL SWLVSKQKDL TAKGQGGSEE 

       430        440        450        460        470        480 
HKAVSRLMAV SNLINQAVGD ALSGVLLVEV ILQHLGWSIE KWNELYKDLP SRQIKVEVPD 

       490        500        510        520        530        540 
RTAVVTTSEE TEALRPMGIQ DAINSEIKKY SRGRAFIRPS GTEDVVRVYA EASTQEDADS 

       550 
LANSVAQLVK SFLGSS 

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence features of the regions of 1,367,185 bp covered by 19 physically assigned P1 and TAC clones."
Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N., Tabata S.
DNA Res. 5:203-216(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Selection of Arabidopsis cDNAs that partially correct phenotypes of Escherichia coli DNA-damage-sensitive mutants and analysis of two plant cDNAs that appear to express UV-specific dark repair activities."
Pang Q., Hays J.B., Rajagopal I., Schaefer T.S.
Plant Mol. Biol. 22:411-426(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 183-556.
Strain: cv. Columbia.
[5]"Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis."
de la Fuente van Bentem S., Anrather D., Dohnal I., Roitinger E., Csaszar E., Joore J., Buijnink J., Carreri A., Forzani C., Lorkovic Z.J., Barta A., Lecourieux D., Verhounig A., Jonak C., Hirt H.
J. Proteome Res. 7:2458-2470(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-68, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Root.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB012246 Genomic DNA. Translation: BAB09465.1.
CP002688 Genomic DNA. Translation: AED92503.1.
AY075620 mRNA. Translation: AAL91631.1.
L11367 mRNA. Translation: AAA72352.1. Sequence problems.
PIRS35270.
RefSeqNP_568359.2. NM_121812.2.
UniGeneAt.466.

3D structure databases

ProteinModelPortalP57750.
SMRP57750. Positions 19-554.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT5G18070.1-P.

Proteomic databases

PaxDbP57750.
PRIDEP57750.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G18070.1; AT5G18070.1; AT5G18070.
GeneID831926.
KEGGath:AT5G18070.

Organism-specific databases

TAIRAT5G18070.

Phylogenomic databases

eggNOGCOG1109.
HOGENOMHOG000210027.
InParanoidP57750.
KOK01836.
OMADIVRVYA.
PhylomeDBP57750.

Enzyme and pathway databases

BioCycARA:AT5G18070-MONOMER.
UniPathwayUPA00113; UER00530.

Gene expression databases

GenevestigatorP57750.

Family and domain databases

Gene3D3.30.310.50. 1 hit.
3.40.120.10. 2 hits.
InterProIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016657. PAGM.
[Graphical view]
PfamPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PIRSFPIRSF016408. PAGM. 1 hit.
SUPFAMSSF53738. SSF53738. 4 hits.
SSF55957. SSF55957. 1 hit.
ProtoNetSearch...

Other

PROP57750.

Entry information

Entry nameAGM1_ARATH
AccessionPrimary (citable) accession number: P57750
Secondary accession number(s): Q05211
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: January 24, 2001
Last modified: June 11, 2014
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names