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Protein

Potassium-transporting ATPase ATP-binding subunit

Gene

kdpB

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system.UniRule annotation

Catalytic activityi

ATP + H2O + K+(Out) = ADP + phosphate + K+(In).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei3184-aspartylphosphate intermediateUniRule annotation1
Binding sitei355ATPUniRule annotation1
Binding sitei359ATPUniRule annotation1
Binding sitei435ATPUniRule annotation1
Metal bindingi554MagnesiumUniRule annotation1
Metal bindingi558MagnesiumUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi416 – 423ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
Biological processIon transport, Potassium transport, Transport
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Potassium

Names & Taxonomyi

Protein namesi
Recommended name:
Potassium-transporting ATPase ATP-binding subunitUniRule annotation (EC:3.6.3.12UniRule annotation)
Alternative name(s):
ATP phosphohydrolase [potassium-transporting] B chainUniRule annotation
Potassium-binding and translocating subunit BUniRule annotation
Potassium-translocating ATPase B chainUniRule annotation
Gene namesi
Name:kdpBUniRule annotation
Ordered Locus Names:VNG_6177G
Encoded oniPlasmid pNRC2000 Publication
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000000554 Componenti: Plasmid pNRC200

Subcellular locationi

P57699:
  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei35 – 55HelicalUniRule annotationAdd BLAST21
Transmembranei62 – 82HelicalUniRule annotationAdd BLAST21
Transmembranei228 – 248HelicalUniRule annotationAdd BLAST21
Transmembranei254 – 274HelicalUniRule annotationAdd BLAST21
Transmembranei624 – 644HelicalUniRule annotationAdd BLAST21
Transmembranei652 – 672HelicalUniRule annotationAdd BLAST21
Transmembranei698 – 718HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000461511 – 719Potassium-transporting ATPase ATP-binding subunitAdd BLAST719

Keywords - PTMi

Phosphoprotein

Interactioni

Subunit structurei

The system is composed of three essential subunits: KdpA, KdpB and KdpC.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliP57699.
SMRiP57699.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiP57699.
KOiK01547.
OMAiILWLWFT.
OrthoDBiPOG093Z00WB.
PhylomeDBiP57699.

Family and domain databases

CDDicd02078. P-type_ATPase_K. 1 hit.
Gene3Di3.40.1110.10. 1 hit.
3.40.50.1000. 1 hit.
HAMAPiMF_00285. KdpB. 1 hit.
InterProiView protein in InterPro
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR036412. HAD-like_sf.
IPR023214. HAD_sf.
IPR006391. P-type_ATPase_bsu_IA.
IPR001757. P_typ_ATPase.
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81653. SSF81653. 1 hit.
SSF81660. SSF81660. 1 hit.
SSF81665. SSF81665. 2 hits.
TIGRFAMsiTIGR01494. ATPase_P-type. 2 hits.
PROSITEiView protein in PROSITE
PS00154. ATPASE_E1_E2. 1 hit.

Sequencei

Sequence statusi: Complete.

P57699-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEITVTIDT DQQKQAISDS FAKLDPQYLV KNPVLFVVEL GTIIGLVMTI
60 70 80 90 100
APGLFGATGS RVYYAVITVL LGFTVIFANY AEAYAELEGE AQADSLRALQ
110 120 130 140 150
TEAEGKLLQN DDVDIEDISE DDYEVVASTE IEQDAVVFVD EGDIIPRDGT
160 170 180 190 200
VVEGSASVDE SAITGESEPV IRQSGGDRTS VVGGTEVLSD RIKVEVTSEE
210 220 230 240 250
GESFLDQMIG LVEDAQRQKT PNEIAMTILL SGLTLVFVVA VATMFFFGEY
260 270 280 290 300
LASFVGGFAG LDVAELVALL VALMPTTIGA LLAAIRVAGM TRVTRRNVIA
310 320 330 340 350
KSGRAVEAAG DLDALILDKT GTITTGERVA QDFHPLGDAD DADVVRASYQ
360 370 380 390 400
SSLYDETTEG RSIVKLAEKM NGKVQTDGGQ SASEELDEPG DSVDAPRDVS
410 420 430 440 450
VTLDAEGLSE SNFVPFSAET RMSGIDLSDG TEIRKGAVDA VEEYATTVPG
460 470 480 490 500
KLRQKSNAIS ESGGTPLAIA VDGQVVGIIE LQDELKPGIA DRIAEIQKMG
510 520 530 540 550
VETIMATGDN QRTARWVADQ VGIDEFHAEF DPEEKIELVE DIQDDGKLVG
560 570 580 590 600
MTGDGTNDAP ALAKADVGLA MNAGTNAAKE AGNMVDLDSN PSKIIEVVGI
610 620 630 640 650
GKQLLMTRGS LTTFSVANDV AKYFVLLPAI LAAAIPGLGA MDILNLSTPA
660 670 680 690 700
SAVTATLMYN AFIIPLLIPL ALRGVDYKAQ SGAQLLRKNL IVYGGGGLIA
710
PFIFIKAIDM LFVALGVFQ
Length:719
Mass (Da):75,986
Last modified:December 8, 2000 - v1
Checksum:iDC3AE79A596BD85A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004438 Genomic DNA. Translation: AAG20844.1.
RefSeqiWP_010904057.1. NC_002608.1.

Genome annotation databases

EnsemblBacteriaiAAG20844; AAG20844; VNG_6177G.
GeneIDi5954966.
KEGGihal:VNG_6177G.
PATRICifig|64091.14.peg.2201.

Similar proteinsi

Entry informationi

Entry nameiKDPB_HALSA
AccessioniPrimary (citable) accession number: P57699
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: December 8, 2000
Last modified: October 25, 2017
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families