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Reviewed, UniProtKB/Swiss-Prot P57681 (PCYOX_ARATH)

Last modified November 3, 2009. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Probable prenylcysteine oxidase
    EC=1.8.3.5
Gene names
Ordered Locus Names: At5g63910
ORF Names: MGI19.4, MGI19.11
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

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Protein attributes

Sequence length500 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine By similarity.

Catalytic activity

An S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2.

Cofactor

FAD By similarity.

Subcellular location

Lysosome By similarity.

Sequence similarities

Belongs to the prenylcysteine oxidase family.

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Ontologies

Keywords
   Cellular componentLysosome
   DomainSignal
   LigandFAD
   Molecular functionOxidoreductase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processfarnesyl diphosphate metabolic process

Inferred from direct assay. Source: TAIR

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

prenylcysteine catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentendomembrane system

Inferred from direct assay. Source: TAIR

lysosome

Inferred from electronic annotation. Source: UniProtKB-SubCell

plasma membrane

Inferred from direct assay. Source: TAIR

   Molecular functionprenylcysteine oxidase activity

Inferred from direct assay. Source: TAIR

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 500476Probable prenylcysteine oxidase
PRO_0000023303

Amino acid modifications

Glycosylation561N-linked (GlcNAc...) Potential
Glycosylation1131N-linked (GlcNAc...) Potential
Glycosylation2111N-linked (GlcNAc...) Potential
Glycosylation2811N-linked (GlcNAc...) Potential

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Sequences

Sequence LengthMass (Da)Tools
P57681-1 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: E60B89C4990AB29A

FASTA50055,298
        10         20         30         40         50         60 
MKDFPIAISL LFALLSPVLL PCSGDSTGGV EDDSPATVCI VGSGIGGSSV AHFLRNYSVS 

        70         80         90        100        110        120 
TGLNQAKILM FERHEIVGGR MRTVTVAGDT FEAGGSILHP KNYHVKDFVE RFNLTVRLPT 

       130        140        150        160        170        180 
PIEESSAIGI WDGKRFVVKT FGSGTKFPFL DTIVSWVNDL YLFLRYGLSL LRMSSFIENT 

       190        200        210        220        230        240 
VDNFLKYYES LESRPIFDNV EGMLKWSGLY NLTKLTLQEK LSEAQLSPLL VNELVTVITR 

       250        260        270        280        290        300 
INYGQSVLIS GLAGAVSLAG SGGGLWSVEG GNWQMAAKLI NHSDVTLHLN EKIESISYLE 

       310        320        330        340        350        360 
NHYELKSTKG NSYKCDVTVV ATPLDEVDIQ FSPTISIPKR ELQHTHTTFV RGLLNPGYFG 

       370        380        390        400        410        420 
MKSLSDVPAL VGTLEDPLIP FSCISILRKY SKTDMTYKIF TRQPASDSLL DELFSRRTET 

       430        440        450        460        470        480 
VRIDWGAYPK YHAPEVFAPF ILDDHHLYYV NAFENAASTM ETSAVAGENI ARLIISRFMT 

       490        500 
KESLSSSDKR SCSSGLHSDS

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Cross-references

Sequence databases

AB007646, AB019227 Genomic DNA. Translation: BAB11039.1.
AY081255 mRNA. Translation: AAL91144.1.
AY128716 mRNA. Translation: AAM91116.1.
IPIIPI00532682.
RefSeqNP_201196.1.
UniGeneAt.43104

3D structure databases

ModBaseSearch...

Proteomic databases

PRIDEP57681.

Genome annotation databases

GeneID836512.
GenomeReviewsGene locus AT5G63910 in contig BA000015_GR.
KEGGath:AT5G63910.
NMPDRfig|3702.1.peg.28446.

Organism-specific databases

TAIRAt5g63910.

Phylogenomic databases

OMASLRMHMW.

Enzyme and pathway databases

BRENDA1.8.3.5. 302.

Gene expression databases

ArrayExpressP57681.
GenevestigatorP57681.
GermOnlineAT5G63910. Arabidopsis thaliana.

Family and domain databases

InterProIPR010795. Prenylcys_lyase.
IPR017046. Prenylcysteine_Oxase.
[Graphical view]
PfamPF07156. Prenylcys_lyase. 1 hit.
[Graphical view]
PIRSFPIRSF036292. Prenylcysteine_oxidase. 1 hit.
ProtoNetSearch...

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Entry information

Entry namePCYOX_ARATH
AccessionPrimary (citable) accession number: P57681
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: November 3, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents