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P57660 (HSCA_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chaperone protein HscA
Gene names
Name:hscA
Ordered Locus Names:BU605
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera ›

Protein attributes

Sequence length611 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU By similarity. HAMAP-Rule MF_00679

Sequence similarities

Belongs to the heat shock protein 70 family.

Ontologies

Keywords
   LigandATP-binding
Nucleotide-binding
   Molecular functionChaperone
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processiron-sulfur cluster assembly

Inferred from electronic annotation. Source: InterPro

protein folding

Inferred from electronic annotation. Source: HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATPase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 611611Chaperone protein HscA HAMAP-Rule MF_00679
PRO_0000078619

Sequences

Sequence LengthMass (Da)Tools
P57660 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 32B567C53073082A

FASTA61169,837
        10         20         30         40         50         60 
MIFFKKKHDK KLLLGIDLGT TYSLAATVRE KSVILLLDKK KRYLLPSVVH YKKNKISVGW 

        70         80         90        100        110        120 
KALENITEDP TNTISSVKRL LGRSINFVKK KFPILPYLIE KDIHEGIFFR TNFGNITPID 

       130        140        150        160        170        180 
VSSHILKKLK KRAVLLFNQE IDASVITVPA YFNDFQKKET KKAAVLSGIN LIRLLNEPTA 

       190        200        210        220        230        240 
AAVAYGLQKL KKGIVLVYDL GGGTFDVSIL NLNKGIFEVL ATSGDSNLGG DDFDDALAKN 

       250        260        270        280        290        300 
IYKKSNLQNR CNDFFQTSLL QIAKSTKLKL TKYEKVEVHF FDWKGYITRE EFNLIIIDFI 

       310        320        330        340        350        360 
KKTLFICSDL LEEINLSVEQ IKEVIMVGGS TRIPLVHTEV SKFFKKDLLK SINPDQVVAI 

       370        380        390        400        410        420 
GAAMHVDMLF SSKNNTKNKV ILLDVMPLSL GIEVMGGFVE KIIFRNTSLP ISKTKEFTTY 

       430        440        450        460        470        480 
KDNQTSILIH IVQGERELVK DCISLSRFVL RDIKPQKAGL VRILVTFQVD TDGLIHVKIL 

       490        500        510        520        530        540 
ENYSSKEKKI IIDNNITLKN LNISQILKDS LKHSKDDYYF RVKEEKKIEC VRTLEILNKS 

       550        560        570        580        590        600 
LKKHLKLISK KELKKIKYTQ EKLQKSIQED DYFSMKNNLQ KLDEVSKNFF SLQLKNAIDC 

       610 
SSIKNILKEN I

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References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000003 Genomic DNA. Translation: BAB13289.1.
RefSeqNP_240403.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57660.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB13289; BAB13289; BAB13289.
GeneID1109940.
KEGGbuc:BU605.
PATRIC21244762. VBIBucAph127364_0607.

Phylogenomic databases

eggNOGCOG0443.
HOGENOMHOG000228136.
KOK04044.
ProtClustDBPRK05183.

Family and domain databases

HAMAPMF_00679. HscA.
InterProIPR018181. Heat_shock_70_CS.
IPR013126. Hsp_70_fam.
IPR010236. ISC_FeS_clus_asmbl_HscA.
[Graphical view]
PfamPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSPR00301. HEATSHOCK70.
TIGRFAMsTIGR01991. HscA. 1 hit.
PROSITEPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHSCA_BUCAI
AccessionPrimary (citable) accession number: P57660
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names

SIMILARITY comments

Index of protein domains and families

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