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Reviewed, UniProtKB/Swiss-Prot P57641 (FENR_BUCAI)

Last modified November 3, 2009. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Ferredoxin--NADP reductase
      Short name=FNR
    EC=1.18.1.2
Alternative name(s):
    Flavodoxin reductase
      Short name=FLXR
      Short name=FLDR
Gene names
Name: fpr
Ordered Locus Names: BU581
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]
Taxonomic identifier118099 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

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Protein attributes

Sequence length252 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Transports electrons between flavodoxin or ferredoxin and NADPH By similarity.

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.

Cofactor

FAD By similarity.

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 1 family.

Contains 1 FAD-binding FR-type domain.

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Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionelectron carrier activity

Inferred from electronic annotation. Source: InterPro

ferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 252252Ferredoxin--NADP reductase
PRO_0000167640

Regions

Domain2 – 105104FAD-binding FR-type
Nucleotide binding54 – 574FAD By similarity
Nucleotide binding77 – 804FAD By similarity
Nucleotide binding147 – 1482NADP By similarity
Nucleotide binding177 – 1782NADP By similarity
Nucleotide binding217 – 2182NADP By similarity

Sites

Binding site571NADP By similarity
Binding site1201FAD By similarity
Binding site1201NADP; via amide nitrogen By similarity
Binding site2491NADP By similarity

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Sequences

Sequence LengthMass (Da)Tools
P57641-1 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: E161A47BBB9BD23B

FASTA25229,537
        10         20         30         40         50         60 
MNPWINADVL MVKKWTKNLF SLILNAPIEP FFAGQFNKLA LYNSNPLNKN KIQRAYSYVN 

        70         80         90        100        110        120 
APSEKNLEIY IVRVLNGQLS NLLYNLHSGD KIFIKKKSFG FFIIDEIPDC EILWMFATGT 

       130        140        150        160        170        180 
GIGPYCSILQ EGKNINRFNH IILTHAVRYQ NELTYLPLMK ELRQKYNGKL QIQTITSREK 

       190        200        210        220        230        240 
HKNSLNGRIP FLLRNKILEK HVGFSINPQT SHVMLCGNPF MVKDTFLFLK NNRNMEKHLR 

       250 
RKKGHITMEN YW

« Hide

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References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed: 10993077] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Tokyo 1998.

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Cross-references

Sequence databases

BA000003 Genomic DNA. Translation: BAB13270.1.
RefSeqNP_240384.1.

3D structure databases

HSSPHSSP built from PDB template 1FDR based on UniProtKB P28861.
ModBaseSearch...

Genome annotation databases

GeneID1109920.
GenomeReviewsGene locus BU581 in contig BA000003_GR.
KEGGbuc:BU581.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP57641.
OMAIMLCGNP.

Enzyme and pathway databases

BioCycBSP107806:BU581-MON.

Family and domain databases

InterProIPR017927. Fd_Rdtase_FAD-bd.
IPR001433. OxRdtase_FAD/NAD_bd.
[Graphical view]
PfamPF00175. NAD_binding_1. 1 hit.
[Graphical view]
PROSITEPS51384. FAD_FR. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameFENR_BUCAI
AccessionPrimary (citable) accession number: P57641
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: November 3, 2009
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents