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P57628 (RNR_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease R

Short name=RNase R
EC=3.1.13.1
Alternative name(s):
VacB protein homolog
Gene names
Name:rnr
Ordered Locus Names:BU565
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length731 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs By similarity. HAMAP-Rule MF_01895

Catalytic activity

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_01895

Subunit structure

Monomer By similarity. HAMAP-Rule MF_01895

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_01895.

Sequence similarities

Belongs to the RNR ribonuclease family. RNase R subfamily.

Contains 1 S1 motif domain.

Sequence caution

The sequence BAB13255.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandRNA-binding
   Molecular functionExonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

exoribonuclease II activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 731731Ribonuclease R HAMAP-Rule MF_01895
PRO_0000166397

Regions

Domain647 – 72882S1 motif

Sequences

Sequence LengthMass (Da)Tools
P57628 [UniParc].

Last modified November 15, 2002. Version 2.
Checksum: 1AED36ACF09CCC2A

FASTA73184,807
        10         20         30         40         50         60 
MVVDPYQKRE AKRYKNPIPS REYISSCLRT SQDLISQKNL EKKFGINNQE SKKALRRRLR 

        70         80         90        100        110        120 
AMERDGQVIY TSNRCYVAPE SLKIVKGKVI GHRDGYGFLR TETLKEDLWL SSEQMKSCIH 

       130        140        150        160        170        180 
GDIILAHIVE THGKRRSSAR FLKLLQPNNI LIVGRYYIDD KIKFVIPDDT RFNFKIFIFS 

       190        200        210        220        230        240 
AIKDDISIGS IVSVKLKQHP IRNSRVQGFI VEILGKEMGT NLAIEIALRT HLIPSLWSKE 

       250        260        270        280        290        300 
VKKQVYEISR KINQYDFKNR TDLRHFPFFT IDDEDARDFD DAVFCKRKAN PEEGWILWVA 

       310        320        330        340        350        360 
IADVSCYVQP NTPLDKAALE RGTSVYFPSL VIPMLPEKIS TDLCSLKPNV ERLCLICEMS 

       370        380        390        400        410        420 
LSKQGELISY KHYEGIICSH GRFTYNEIFK IWNGDIFLRS KYKKFLKDIE NLSCLQNIFN 

       430        440        450        460        470        480 
KDNISKKGIY FENIEPKFVL DSNLRIKSIY QNIRNDAHKF IESCMILANV ASARFVEKYK 

       490        500        510        520        530        540 
YPVLFRNHDR PKKDNVVSLR LFLNELGFTL LGGDSPESVH YSNLLKNVSD RPEYEMIQTV 

       550        560        570        580        590        600 
LLRSMTQAVY SPDNRGHFGL SLSSYVHFTS PIRRYPDLIL HRVIKYLLFK DKNTSKSNYN 

       610        620        630        640        650        660 
FYSAHLYSTG EIKKIGAHCS ITERRADEAN RDVIDWLKCD FMYKKIGCIL NGVISNVTTF 

       670        680        690        700        710        720 
GFFVRLNQFF IDGLVHINSL NDDYYYFDSL GLKLIGKSTK NTYCLGDALK VKVISVNLNE 

       730 
KKIELSLYKS S 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB13255.1. Different initiation.
RefSeqNP_240369.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57628.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP57628.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB13255; BAB13255; BAB13255.
GeneID1109905.
KEGGbuc:BU565.
PATRIC21244674. VBIBucAph127364_0568.

Phylogenomic databases

eggNOGCOG0557.
HOGENOMHOG000071120.
KOK12573.
OMAGFFVRLN.
OrthoDBEOG6Q5NRD.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-565-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_01895. RNase_R.
InterProIPR011129. Cold_shock_prot.
IPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR022967. RNA-binding_domain_S1.
IPR013223. RNase_B_OB_dom.
IPR022966. RNase_II/R_CS.
IPR004476. RNase_II/RNase_R.
IPR011805. RNase_R.
[Graphical view]
PfamPF08206. OB_RNB. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTSM00357. CSP. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMSSF50249. SSF50249. 4 hits.
TIGRFAMsTIGR00358. 3_prime_RNase. 1 hit.
TIGR02063. RNase_R. 1 hit.
PROSITEPS01175. RIBONUCLEASE_II. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNR_BUCAI
AccessionPrimary (citable) accession number: P57628
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 15, 2002
Last modified: May 14, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names