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Protein

Ribonuclease R

Gene

rnr

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-565-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease RUniRule annotation (EC:3.1.13.1UniRule annotation)
Short name:
RNase RUniRule annotation
Alternative name(s):
VacB protein homolog
Gene namesi
Name:rnrUniRule annotation
Ordered Locus Names:BU565
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 731731Ribonuclease RPRO_0000166397Add
BLAST

Proteomic databases

PRIDEiP57628.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi107806.BU565.

Structurei

3D structure databases

ProteinModelPortaliP57628.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini647 – 72882S1 motifUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the RNR ribonuclease family. RNase R subfamily.UniRule annotation
Contains 1 S1 motif domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0557.
HOGENOMiHOG000071120.
KOiK12573.
OMAiGFFVRLN.
OrthoDBiEOG6Q5NRD.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_01895. RNase_R.
InterProiIPR011129. Cold_shock_prot.
IPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR013223. RNase_B_OB_dom.
IPR022966. RNase_II/R_CS.
IPR004476. RNase_II/RNase_R.
IPR011805. RNase_R.
IPR022967. S1_dom.
[Graphical view]
PfamiPF08206. OB_RNB. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTiSM00357. CSP. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 4 hits.
TIGRFAMsiTIGR00358. 3_prime_RNase. 1 hit.
TIGR02063. RNase_R. 1 hit.
PROSITEiPS01175. RIBONUCLEASE_II. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57628-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVDPYQKRE AKRYKNPIPS REYISSCLRT SQDLISQKNL EKKFGINNQE
60 70 80 90 100
SKKALRRRLR AMERDGQVIY TSNRCYVAPE SLKIVKGKVI GHRDGYGFLR
110 120 130 140 150
TETLKEDLWL SSEQMKSCIH GDIILAHIVE THGKRRSSAR FLKLLQPNNI
160 170 180 190 200
LIVGRYYIDD KIKFVIPDDT RFNFKIFIFS AIKDDISIGS IVSVKLKQHP
210 220 230 240 250
IRNSRVQGFI VEILGKEMGT NLAIEIALRT HLIPSLWSKE VKKQVYEISR
260 270 280 290 300
KINQYDFKNR TDLRHFPFFT IDDEDARDFD DAVFCKRKAN PEEGWILWVA
310 320 330 340 350
IADVSCYVQP NTPLDKAALE RGTSVYFPSL VIPMLPEKIS TDLCSLKPNV
360 370 380 390 400
ERLCLICEMS LSKQGELISY KHYEGIICSH GRFTYNEIFK IWNGDIFLRS
410 420 430 440 450
KYKKFLKDIE NLSCLQNIFN KDNISKKGIY FENIEPKFVL DSNLRIKSIY
460 470 480 490 500
QNIRNDAHKF IESCMILANV ASARFVEKYK YPVLFRNHDR PKKDNVVSLR
510 520 530 540 550
LFLNELGFTL LGGDSPESVH YSNLLKNVSD RPEYEMIQTV LLRSMTQAVY
560 570 580 590 600
SPDNRGHFGL SLSSYVHFTS PIRRYPDLIL HRVIKYLLFK DKNTSKSNYN
610 620 630 640 650
FYSAHLYSTG EIKKIGAHCS ITERRADEAN RDVIDWLKCD FMYKKIGCIL
660 670 680 690 700
NGVISNVTTF GFFVRLNQFF IDGLVHINSL NDDYYYFDSL GLKLIGKSTK
710 720 730
NTYCLGDALK VKVISVNLNE KKIELSLYKS S
Length:731
Mass (Da):84,807
Last modified:November 15, 2002 - v2
Checksum:i1AED36ACF09CCC2A
GO

Sequence cautioni

The sequence BAB13255.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB13255.1. Different initiation.
RefSeqiNP_240369.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB13255; BAB13255; BAB13255.
GeneIDi1109905.
KEGGibuc:BU565.
PATRICi21244674. VBIBucAph127364_0568.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB13255.1. Different initiation.
RefSeqiNP_240369.1. NC_002528.1.

3D structure databases

ProteinModelPortaliP57628.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi107806.BU565.

Proteomic databases

PRIDEiP57628.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB13255; BAB13255; BAB13255.
GeneIDi1109905.
KEGGibuc:BU565.
PATRICi21244674. VBIBucAph127364_0568.

Phylogenomic databases

eggNOGiCOG0557.
HOGENOMiHOG000071120.
KOiK12573.
OMAiGFFVRLN.
OrthoDBiEOG6Q5NRD.

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-565-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_01895. RNase_R.
InterProiIPR011129. Cold_shock_prot.
IPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR013223. RNase_B_OB_dom.
IPR022966. RNase_II/R_CS.
IPR004476. RNase_II/RNase_R.
IPR011805. RNase_R.
IPR022967. S1_dom.
[Graphical view]
PfamiPF08206. OB_RNB. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTiSM00357. CSP. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 4 hits.
TIGRFAMsiTIGR00358. 3_prime_RNase. 1 hit.
TIGR02063. RNase_R. 1 hit.
PROSITEiPS01175. RIBONUCLEASE_II. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiRNR_BUCAI
AccessioniPrimary (citable) accession number: P57628
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 15, 2002
Last modified: June 24, 2015
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.