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Reviewed, UniProtKB/Swiss-Prot P57604 (AROB_BUCAI)

Last modified November 3, 2009. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    3-dehydroquinate synthase
    EC=4.2.3.4
Gene names
Name: aroB
Ordered Locus Names: BU538
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]
Taxonomic identifier118099 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

NAD By similarity.

Divalent metal cations By similarity.

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm Probable.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3633633-dehydroquinate synthase HAMAP MF_00110
PRO_0000140717

Sequences

Sequence LengthMass (Da)Tools
P57604-1 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 1DB8EC7B8D8F6EC8

FASTA36340,297
        10         20         30         40         50         60 
MKIVERLQVV LGERSYPISI GAGIIQEDDI FWPLKPGDQA MLVTNKTLAN LLKDKVFYHL 

        70         80         90        100        110        120 
RKSGIKIDQV ILSDGEQYKT LNEMELIISA LLEKKHARDT TLIALGGGVI GDLAGFAASV 

       130        140        150        160        170        180 
YQRGVRFIQI PTTLLSQVDA SVGGKTAVNH LLGKNMIGSF WQPSSVIIDI DCLKTLPYNE 

       190        200        210        220        230        240 
LVSGMAEVIK YAIVFDKTFF CWLEENIESI LSLNHTAMSY CIKKCCELKS QLIALDEREN 

       250        260        270        280        290        300 
NLRALLNLGH TYGHAIEVHA GYGNWLHGEA ISVGMVMAAR TSELLGHLKT IDFKRILVLL 

       310        320        330        340        350        360 
KRTGLPIKGP KNMSAASYLP YMMRDKKVIS GEMRLVLPLS IGKAEIYSNI DKNIILTAIK 


HSQ 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed: 10993077] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Tokyo 1998.

Cross-references

Sequence databases

BA000003 Genomic DNA. Translation: BAB13231.1.
RefSeqNP_240345.1.

3D structure databases

HSSPHSSP built from PDB template 1DQS based on UniProtKB P07547.
ModBaseSearch...

Genome annotation databases

GeneID1109881.
GenomeReviewsGene locus BU538 in contig BA000003_GR.
KEGGbuc:BU538.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP57604.
OMAEDYLPHM.

Enzyme and pathway databases

BioCycBSP107806:BU538-MON.

Family and domain databases

HAMAPMF_00110.
[Tree]
InterProIPR016303. DHQ_synth.
IPR002658. DHQ_synth_AroB.
IPR016037. DHQ_synth_AroB_sub.
[Graphical view]
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PfamPF01761. DHQ_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. aroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_BUCAI
AccessionPrimary (citable) accession number: P57604
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: November 3, 2009
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents