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Protein

Ribulose-phosphate 3-epimerase

Gene

rpe

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.By similarity

Catalytic activityi

D-ribulose 5-phosphate = D-xylulose 5-phosphate.

Cofactori

Co2+By similarity, Fe2+By similarity, Mn2+By similarity, Zn2+By similarityNote: Binds 1 divalent metal cation per subunit. Active with Co2+, Fe2+, Mn2+ and Zn2+.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei9SubstrateBy similarity1
Metal bindingi34Divalent metal cationBy similarity1
Active sitei36Proton acceptorBy similarity1
Metal bindingi36Divalent metal cationBy similarity1
Metal bindingi68Divalent metal cationBy similarity1
Binding sitei68SubstrateBy similarity1
Active sitei177Proton donorBy similarity1
Metal bindingi177Divalent metal cationBy similarity1
Binding sitei179Substrate; via amide nitrogenBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism
LigandCobalt, Iron, Manganese, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose-phosphate 3-epimerase (EC:5.1.3.1)
Alternative name(s):
Pentose-5-phosphate 3-epimerase
Short name:
PPE
R5P3E
Gene namesi
Name:rpe
Ordered Locus Names:BU537
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000001806 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001715621 – 228Ribulose-phosphate 3-epimeraseAdd BLAST228

Interactioni

Protein-protein interaction databases

STRINGi107806.BU537.

Structurei

3D structure databases

ProteinModelPortaliP57603.
SMRiP57603.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni144 – 147Substrate bindingBy similarity4
Regioni199 – 200Substrate bindingBy similarity2

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105DJV. Bacteria.
COG0036. LUCA.
HOGENOMiHOG000259347.
KOiK01783.
OMAiCHLMIED.

Family and domain databases

CDDicd00429. RPE. 1 hit.
Gene3Di3.20.20.70. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR026019. Ribul_P_3_epim.
IPR000056. Ribul_P_3_epim-like.
IPR011060. RibuloseP-bd_barrel.
PANTHERiPTHR11749. PTHR11749. 1 hit.
PfamiView protein in Pfam
PF00834. Ribul_P_3_epim. 1 hit.
PIRSFiPIRSF001461. RPE. 1 hit.
SUPFAMiSSF51366. SSF51366. 1 hit.
TIGRFAMsiTIGR01163. rpe. 1 hit.
PROSITEiView protein in PROSITE
PS01085. RIBUL_P_3_EPIMER_1. 1 hit.
PS01086. RIBUL_P_3_EPIMER_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P57603-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKFFLAPSI LSADFARLGE DIKKVIDAGS DLIHFDVMDN HYVPNLSMGP
60 70 80 90 100
MILESLRNYN ITAPIDVHLM VKPVDNLIPQ FAKAGATFIT FHPEATLHIE
110 120 130 140 150
RTLNLIKENG CKAGLAFNPA TPLNFLDYIL EKLDLILLMS VNPGFGNQSF
160 170 180 190 200
LPSTFNKLRE VRKIIDANFS DILLEVDGGV KLDNIADIAC AGANVFVMGS
210 220
GLFKYSNYKL VIEKIRKKLE YAHSRSIH
Length:228
Mass (Da):25,410
Last modified:December 1, 2000 - v1
Checksum:i797346400A81AC51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB13230.1.
RefSeqiNP_240344.1. NC_002528.1.
WP_009874488.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB13230; BAB13230; BAB13230.
GeneIDi1109880.
KEGGibuc:BU537.
PATRICifig|107806.10.peg.542.

Similar proteinsi

Entry informationi

Entry nameiRPE_BUCAI
AccessioniPrimary (citable) accession number: P57603
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: June 7, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families