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P57599 (FKBA_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA

Short name=PPIase
EC=5.2.1.8
Alternative name(s):
Rotamase
Gene names
Name:fkpA
Ordered Locus Names:BU533
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length241 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Catalytic activity

Peptidylproline (omega=180) = peptidylproline (omega=0).

Sequence similarities

Belongs to the FKBP-type PPIase family.

Contains 1 PPIase FKBP-type domain.

Ontologies

Keywords
   Molecular functionIsomerase
Rotamase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionpeptidyl-prolyl cis-trans isomerase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 241241FKBP-type peptidyl-prolyl cis-trans isomerase FkpA
PRO_0000075364

Regions

Domain153 – 24189PPIase FKBP-type

Sequences

Sequence LengthMass (Da)Tools
P57599 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 55D5E99740188C3F

FASTA24126,946
        10         20         30         40         50         60 
MILYVPKSFS ISAPISDIHL QSVLETKNTF HNNNEKLGYI LGLSFGNYVN QTFEKQKKIG 

        70         80         90        100        110        120 
IELDRNSLLK GIQDAISGNL KLSHQDISSG LKELEKKLKH ATKIQLKKNA KENFIQGELY 

       130        140        150        160        170        180 
MKNFSKLKGV KKTSSGLLYL LERAGEGEAL KDETKITVHY KGTLINGLEF DNSYKRGRPV 

       190        200        210        220        230        240 
SLRLKDVILG WKEGLKYIKK GGKIKLVIPP NLAYGTEEVN GIPANSTLIF DIELLDVVNG 


V 

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References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB13226.1.
RefSeqNP_240340.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57599.
SMRP57599. Positions 30-237.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB13226; BAB13226; BAB13226.
GeneID1109876.
KEGGbuc:BU533.
PATRIC21244608. VBIBucAph127364_0538.

Phylogenomic databases

eggNOGCOG0545.
HOGENOMHOG000154888.
KOK03772.
OMAGKAVHFK.
OrthoDBEOG6DRPKW.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-533-MONOMER.

Family and domain databases

Gene3D1.10.287.460. 1 hit.
InterProIPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
IPR000774. PPIase_FKBP_N.
[Graphical view]
PANTHERPTHR10516. PTHR10516. 1 hit.
PfamPF00254. FKBP_C. 1 hit.
PF01346. FKBP_N. 1 hit.
[Graphical view]
PROSITEPS50059. FKBP_PPIASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFKBA_BUCAI
AccessionPrimary (citable) accession number: P57599
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names