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P57599

- FKBA_BUCAI

UniProt

P57599 - FKBA_BUCAI

Protein

FKBP-type peptidyl-prolyl cis-trans isomerase FkpA

Gene

fkpA

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Dec 2000)
      Previous versions | rss
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    Functioni

    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

    Catalytic activityi

    Peptidylproline (omega=180) = peptidylproline (omega=0).

    GO - Molecular functioni

    1. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-KW

    GO - Biological processi

    1. protein folding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Isomerase, Rotamase

    Enzyme and pathway databases

    BioCyciBAPH107806:GBZJ-533-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    FKBP-type peptidyl-prolyl cis-trans isomerase FkpA (EC:5.2.1.8)
    Short name:
    PPIase
    Alternative name(s):
    Rotamase
    Gene namesi
    Name:fkpA
    Ordered Locus Names:BU533
    OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
    Taxonomic identifieri107806 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000001806: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 241241FKBP-type peptidyl-prolyl cis-trans isomerase FkpAPRO_0000075364Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP57599.
    SMRiP57599. Positions 30-237.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini153 – 24189PPIase FKBP-typePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the FKBP-type PPIase family.Curated
    Contains 1 PPIase FKBP-type domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0545.
    HOGENOMiHOG000154888.
    KOiK03772.
    OMAiGKAVHFK.
    OrthoDBiEOG6DRPKW.

    Family and domain databases

    Gene3Di1.10.287.460. 1 hit.
    InterProiIPR023566. PPIase_FKBP.
    IPR001179. PPIase_FKBP_dom.
    IPR000774. PPIase_FKBP_N.
    [Graphical view]
    PANTHERiPTHR10516. PTHR10516. 1 hit.
    PfamiPF00254. FKBP_C. 1 hit.
    PF01346. FKBP_N. 1 hit.
    [Graphical view]
    PROSITEiPS50059. FKBP_PPIASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P57599-1 [UniParc]FASTAAdd to Basket

    « Hide

    MILYVPKSFS ISAPISDIHL QSVLETKNTF HNNNEKLGYI LGLSFGNYVN    50
    QTFEKQKKIG IELDRNSLLK GIQDAISGNL KLSHQDISSG LKELEKKLKH 100
    ATKIQLKKNA KENFIQGELY MKNFSKLKGV KKTSSGLLYL LERAGEGEAL 150
    KDETKITVHY KGTLINGLEF DNSYKRGRPV SLRLKDVILG WKEGLKYIKK 200
    GGKIKLVIPP NLAYGTEEVN GIPANSTLIF DIELLDVVNG V 241
    Length:241
    Mass (Da):26,946
    Last modified:December 1, 2000 - v1
    Checksum:i55D5E99740188C3F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB13226.1.
    RefSeqiNP_240340.1. NC_002528.1.

    Genome annotation databases

    EnsemblBacteriaiBAB13226; BAB13226; BAB13226.
    GeneIDi1109876.
    KEGGibuc:BU533.
    PATRICi21244608. VBIBucAph127364_0538.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB13226.1 .
    RefSeqi NP_240340.1. NC_002528.1.

    3D structure databases

    ProteinModelPortali P57599.
    SMRi P57599. Positions 30-237.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB13226 ; BAB13226 ; BAB13226 .
    GeneIDi 1109876.
    KEGGi buc:BU533.
    PATRICi 21244608. VBIBucAph127364_0538.

    Phylogenomic databases

    eggNOGi COG0545.
    HOGENOMi HOG000154888.
    KOi K03772.
    OMAi GKAVHFK.
    OrthoDBi EOG6DRPKW.

    Enzyme and pathway databases

    BioCyci BAPH107806:GBZJ-533-MONOMER.

    Family and domain databases

    Gene3Di 1.10.287.460. 1 hit.
    InterProi IPR023566. PPIase_FKBP.
    IPR001179. PPIase_FKBP_dom.
    IPR000774. PPIase_FKBP_N.
    [Graphical view ]
    PANTHERi PTHR10516. PTHR10516. 1 hit.
    Pfami PF00254. FKBP_C. 1 hit.
    PF01346. FKBP_N. 1 hit.
    [Graphical view ]
    PROSITEi PS50059. FKBP_PPIASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
      Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
      Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: APS.

    Entry informationi

    Entry nameiFKBA_BUCAI
    AccessioniPrimary (citable) accession number: P57599
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: December 1, 2000
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
      Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3