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Protein

50S ribosomal protein L3

Gene

rplC

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-524-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L3UniRule annotation
Gene namesi
Name:rplCUniRule annotation
Ordered Locus Names:BU524
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 20920950S ribosomal protein L3PRO_0000077077Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei150 – 1501N5-methylglutamineUniRule annotation

Post-translational modificationi

Methylated by PrmB.UniRule annotation

Keywords - PTMi

Methylation

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.UniRule annotation

Protein-protein interaction databases

STRINGi107806.BU524.

Structurei

3D structure databases

ProteinModelPortaliP57591.
SMRiP57591. Positions 1-208.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L3P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0087.
HOGENOMiHOG000100368.
KOiK02906.
OMAiVFKGLRM.
OrthoDBiEOG6WDSMH.

Family and domain databases

HAMAPiMF_01325_B. Ribosomal_L3_B.
InterProiIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERiPTHR11229. PTHR11229. 1 hit.
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
TIGRFAMsiTIGR03625. L3_bact. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57591-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGLVGKKIG MTRIFTEEGT SIPVTVIELK ENRITQVKNI NTDLYCAIQV
60 70 80 90 100
TTGIKKSNRL NKPQSGHFLK SGVTPGRGLW EFRTDKNNNF KIGQSITINI
110 120 130 140 150
FNNVKKVDIT GISKGKGFSG TVKRWNFHTQ DATHGNSLSH RVPGSIGQNQ
160 170 180 190 200
TPGRVFKGKK MAGQLGNTRV TVQSLNIVRI DEHRNLLLVK GAVPGATGSD

LIVKPAIKV
Length:209
Mass (Da):22,841
Last modified:December 1, 2000 - v1
Checksum:iCF0D7F60C828C76F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB13217.1.
RefSeqiNP_240331.1. NC_002528.1.
WP_010896149.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB13217; BAB13217; BAB13217.
GeneIDi1109867.
KEGGibuc:BU524.
PATRICi21244590. VBIBucAph127364_0529.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB13217.1.
RefSeqiNP_240331.1. NC_002528.1.
WP_010896149.1. NC_002528.1.

3D structure databases

ProteinModelPortaliP57591.
SMRiP57591. Positions 1-208.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi107806.BU524.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB13217; BAB13217; BAB13217.
GeneIDi1109867.
KEGGibuc:BU524.
PATRICi21244590. VBIBucAph127364_0529.

Phylogenomic databases

eggNOGiCOG0087.
HOGENOMiHOG000100368.
KOiK02906.
OMAiVFKGLRM.
OrthoDBiEOG6WDSMH.

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-524-MONOMER.

Family and domain databases

HAMAPiMF_01325_B. Ribosomal_L3_B.
InterProiIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERiPTHR11229. PTHR11229. 1 hit.
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
TIGRFAMsiTIGR03625. L3_bact. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiRL3_BUCAI
AccessioniPrimary (citable) accession number: P57591
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: July 22, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.