Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P57540

- CYOE_BUCAI

UniProt

P57540 - CYOE_BUCAI

Protein

Protoheme IX farnesyltransferase

Gene

cyoE

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 Dec 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. protoheme IX farnesyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. heme O biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Heme biosynthesis

    Enzyme and pathway databases

    BioCyciBAPH107806:GBZJ-468-MONOMER.
    UniPathwayiUPA00834; UER00712.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protoheme IX farnesyltransferaseUniRule annotation (EC:2.5.1.-UniRule annotation)
    Alternative name(s):
    Heme B farnesyltransferaseUniRule annotation
    Heme O synthaseUniRule annotation
    Gene namesi
    Name:cyoEUniRule annotation
    Ordered Locus Names:BU468
    OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
    Taxonomic identifieri107806 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000001806: Chromosome

    Subcellular locationi

    Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 285285Protoheme IX farnesyltransferasePRO_0000162898Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP57540.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei8 – 2821HelicalUniRule annotationAdd
    BLAST
    Transmembranei36 – 5621HelicalUniRule annotationAdd
    BLAST
    Transmembranei80 – 10021HelicalUniRule annotationAdd
    BLAST
    Transmembranei107 – 12721HelicalUniRule annotationAdd
    BLAST
    Transmembranei133 – 15321HelicalUniRule annotationAdd
    BLAST
    Transmembranei163 – 18321HelicalUniRule annotationAdd
    BLAST
    Transmembranei209 – 22921HelicalUniRule annotationAdd
    BLAST
    Transmembranei232 – 25221HelicalUniRule annotationAdd
    BLAST
    Transmembranei265 – 28521HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0109.
    HOGENOMiHOG000237290.
    KOiK02301.
    OMAiFATSLWW.
    OrthoDBiEOG6DVJQB.

    Family and domain databases

    HAMAPiMF_00154. CyoE_CtaB.
    InterProiIPR006369. Protohaem_IX_farnesylTrfase.
    IPR000537. UbiA_prenyltransferase.
    [Graphical view]
    PfamiPF01040. UbiA. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01473. cyoE_ctaB. 1 hit.
    PROSITEiPS00943. UBIA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P57540-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFKNYIEITK PGIIIGNSTL ITGGFLFASR HAAFNYVLFI YTILGASLVI    50
    ASACVFNNLI DIDIDKKMKR TSNRVLSKKL LPVFSVFNFA IFLGVLGLSI 100
    LGCLVNFISM SLAVFGFFIY VVLYTMFYKR RSFYSTFIGS FSGSTPSVIG 150
    YTAVSNTIDI CSILLFVIVI FWQMSHFYSI SIMRIKDYRE AKIPVFSVVK 200
    GVAITKKHIF FYVLNFSFFS SLFTFLGYLS YNFLLLSSIV NFYWSFLSYS 250
    NIKKNNDKKN ARKLFYFSII VIVFFNFLIS IDVFF 285
    Length:285
    Mass (Da):32,686
    Last modified:December 1, 2000 - v1
    Checksum:i46504A297D4A16EF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB13165.1.
    RefSeqiNP_240279.1. NC_002528.1.

    Genome annotation databases

    EnsemblBacteriaiBAB13165; BAB13165; BAB13165.
    GeneIDi1109815.
    KEGGibuc:BU468.
    PATRICi21244478. VBIBucAph127364_0477.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB13165.1 .
    RefSeqi NP_240279.1. NC_002528.1.

    3D structure databases

    ProteinModelPortali P57540.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB13165 ; BAB13165 ; BAB13165 .
    GeneIDi 1109815.
    KEGGi buc:BU468.
    PATRICi 21244478. VBIBucAph127364_0477.

    Phylogenomic databases

    eggNOGi COG0109.
    HOGENOMi HOG000237290.
    KOi K02301.
    OMAi FATSLWW.
    OrthoDBi EOG6DVJQB.

    Enzyme and pathway databases

    UniPathwayi UPA00834 ; UER00712 .
    BioCyci BAPH107806:GBZJ-468-MONOMER.

    Family and domain databases

    HAMAPi MF_00154. CyoE_CtaB.
    InterProi IPR006369. Protohaem_IX_farnesylTrfase.
    IPR000537. UbiA_prenyltransferase.
    [Graphical view ]
    Pfami PF01040. UbiA. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01473. cyoE_ctaB. 1 hit.
    PROSITEi PS00943. UBIA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
      Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
      Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: APS.

    Entry informationi

    Entry nameiCYOE_BUCAI
    AccessioniPrimary (citable) accession number: P57540
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: December 1, 2000
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.UniRule annotation

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
      Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3