ID   Y466_BUCAI              Reviewed;         390 AA.
AC   P57538;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   27-MAR-2024, entry version 109.
DE   RecName: Full=Uncharacterized transporter BU466;
GN   OrderedLocusNames=BU466;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; BA000003; BAB13163.1; -; Genomic_DNA.
DR   RefSeq; NP_240277.1; NC_002528.1.
DR   RefSeq; WP_010896131.1; NC_002528.1.
DR   AlphaFoldDB; P57538; -.
DR   SMR; P57538; -.
DR   STRING; 563178.BUAP5A_459; -.
DR   EnsemblBacteria; BAB13163; BAB13163; BAB13163.
DR   KEGG; buc:BU466; -.
DR   PATRIC; fig|107806.10.peg.475; -.
DR   eggNOG; COG2814; Bacteria.
DR   HOGENOM; CLU_001265_10_0_6; -.
DR   BioCyc; BAPH107806:GBZJ-459-MONOMER; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd17472; MFS_YajR_like; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR23517:SF2; MULTIDRUG RESISTANCE PROTEIN MDTH; 1.
DR   PANTHER; PTHR23517; RESISTANCE PROTEIN MDTM, PUTATIVE-RELATED-RELATED; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..390
FT                   /note="Uncharacterized transporter BU466"
FT                   /id="PRO_0000173412"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        272..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        298..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        341..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   390 AA;  45349 MW;  27A7BFF4CEC15620 CRC64;
     MNFLELQVTL SFCVIFLLRM LGMFMILPIL SKYGMLLDGG NKFLIGLSMG IYGISQVIFQ
     IPFGILSDKF NRKKIILLGL FMFFIGNIIS ASIHSIWGLI IGRFFQGSGA ISGVCMAFLS
     DLIREENRVK SIAAIGVSFA ISFLIAVVSG PIIVHYFGFF SIFWISAFLS IVCMIIVCFF
     VPFSKKNILK QNKTLHSYKK VLNFVLNKVF FRFYLGVFFL HFLLMIKFTM IPNQFEISGF
     SLDNHWKVYL GTILISFFVL FLFIFYCKYK YILENIIEIC ILFILFSEII FLSAQKNLLF
     LIISLQIFFI SFNFLEVFLS SHLSRQLSNN YRGSIMSIYS TSQFLGIFFG GVFSGWLYSF
     LNFSQIFYFE LFIILLWLIF SFFLRNRFYL
//