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P57533

- RIBD1_BUCAI

UniProt

P57533 - RIBD1_BUCAI

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Protein
Diaminohydroxyphosphoribosylamino-pyrimidine deaminase
Gene
ribD1, BU461
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + H2O = 5-amino-6-(5-phosphoribosylamino)uracil + NH3.

Cofactori

Binds 1 zinc ion By similarity.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi50 – 501Zinc; catalytic By similarity
Active sitei52 – 521Proton donor By similarity
Metal bindingi75 – 751Zinc; catalytic By similarity
Metal bindingi84 – 841Zinc; catalytic By similarity

GO - Molecular functioni

  1. diaminohydroxyphosphoribosylaminopyrimidine deaminase activity Source: UniProtKB-EC
  2. zinc ion binding Source: InterPro

GO - Biological processi

  1. oxidation-reduction process Source: InterPro
  2. riboflavin biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Riboflavin biosynthesis

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-461-MONOMER.
UniPathwayiUPA00275; UER00401.

Names & Taxonomyi

Protein namesi
Recommended name:
Diaminohydroxyphosphoribosylamino-pyrimidine deaminase (EC:3.5.4.26)
Short name:
DRAP deaminase
Alternative name(s):
Riboflavin-specific deaminase
Gene namesi
Name:ribD1
Ordered Locus Names:BU461
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 147147Diaminohydroxyphosphoribosylamino-pyrimidine deaminase
PRO_0000171725Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP57533.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0117.
HOGENOMiHOG000085050.
KOiK01498.
OMAiLEPCSFV.
OrthoDBiEOG66F07R.

Family and domain databases

InterProiIPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR016193. Cytidine_deaminase-like.
IPR004794. Eubact_RibD.
[Graphical view]
PfamiPF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view]
SUPFAMiSSF53927. SSF53927. 1 hit.
TIGRFAMsiTIGR00326. eubact_ribD. 1 hit.
PROSITEiPS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57533-1 [UniParc]FASTAAdd to Basket

« Hide

MNDIFYMKRA IELSKLGEFT TAPNPNVGCV IVKNNIIVGE GWHEQAGKNH    50
AEINALIMAG EKAQGGTAYV TLEPCNHFGK TPPCCNALIK SGINRVVISN 100
IDPNPKISGN GILYLKKHGI CVKTGLLSKE SKQYNKGFFK RMKTGFP 147
Length:147
Mass (Da):16,049
Last modified:February 11, 2002 - v2
Checksum:i7E4753A37EDFE506
GO

Sequence cautioni

The sequence BAB13158.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB13158.1. Different initiation.
RefSeqiNP_240272.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB13158; BAB13158; BAB13158.
GeneIDi1109808.
KEGGibuc:BU461.
PATRICi21244464. VBIBucAph127364_0470.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB13158.1 . Different initiation.
RefSeqi NP_240272.1. NC_002528.1.

3D structure databases

ProteinModelPortali P57533.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB13158 ; BAB13158 ; BAB13158 .
GeneIDi 1109808.
KEGGi buc:BU461.
PATRICi 21244464. VBIBucAph127364_0470.

Phylogenomic databases

eggNOGi COG0117.
HOGENOMi HOG000085050.
KOi K01498.
OMAi LEPCSFV.
OrthoDBi EOG66F07R.

Enzyme and pathway databases

UniPathwayi UPA00275 ; UER00401 .
BioCyci BAPH107806:GBZJ-461-MONOMER.

Family and domain databases

InterProi IPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR016193. Cytidine_deaminase-like.
IPR004794. Eubact_RibD.
[Graphical view ]
Pfami PF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view ]
SUPFAMi SSF53927. SSF53927. 1 hit.
TIGRFAMsi TIGR00326. eubact_ribD. 1 hit.
PROSITEi PS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiRIBD1_BUCAI
AccessioniPrimary (citable) accession number: P57533
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 11, 2002
Last sequence update: February 11, 2002
Last modified: May 14, 2014
This is version 79 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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