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P57533 (RIBD1_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Diaminohydroxyphosphoribosylamino-pyrimidine deaminase

Short name=DRAP deaminase
EC=3.5.4.26
Alternative name(s):
Riboflavin-specific deaminase
Gene names
Name:ribD1
Ordered Locus Names:BU461
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length147 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + H2O = 5-amino-6-(5-phosphoribosylamino)uracil + NH3.

Cofactor

Binds 1 zinc ion By similarity.

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.

Sequence similarities

Belongs to the cytidine and deoxycytidylate deaminase family.

Sequence caution

The sequence BAB13158.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 147147Diaminohydroxyphosphoribosylamino-pyrimidine deaminase
PRO_0000171725

Sites

Active site521Proton donor By similarity
Metal binding501Zinc; catalytic By similarity
Metal binding751Zinc; catalytic By similarity
Metal binding841Zinc; catalytic By similarity

Sequences

Sequence LengthMass (Da)Tools
P57533 [UniParc].

Last modified February 11, 2002. Version 2.
Checksum: 7E4753A37EDFE506

FASTA14716,049
        10         20         30         40         50         60 
MNDIFYMKRA IELSKLGEFT TAPNPNVGCV IVKNNIIVGE GWHEQAGKNH AEINALIMAG 

        70         80         90        100        110        120 
EKAQGGTAYV TLEPCNHFGK TPPCCNALIK SGINRVVISN IDPNPKISGN GILYLKKHGI 

       130        140 
CVKTGLLSKE SKQYNKGFFK RMKTGFP 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB13158.1. Different initiation.
RefSeqNP_240272.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57533.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB13158; BAB13158; BAB13158.
GeneID1109808.
KEGGbuc:BU461.
PATRIC21244464. VBIBucAph127364_0470.

Phylogenomic databases

eggNOGCOG0117.
HOGENOMHOG000085050.
KOK01498.
OMALEPCSFV.
OrthoDBEOG66F07R.
ProtClustDBCLSK538362.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-461-MONOMER.
UniPathwayUPA00275; UER00401.

Family and domain databases

InterProIPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR016193. Cytidine_deaminase-like.
IPR004794. Eubact_RibD.
[Graphical view]
PfamPF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view]
SUPFAMSSF53927. SSF53927. 1 hit.
TIGRFAMsTIGR00326. eubact_ribD. 1 hit.
PROSITEPS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRIBD1_BUCAI
AccessionPrimary (citable) accession number: P57533
Entry history
Integrated into UniProtKB/Swiss-Prot: February 11, 2002
Last sequence update: February 11, 2002
Last modified: November 13, 2013
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names