P57527 (Y452_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized MscS family protein BU452

Gene names

Ordered Locus Names:

BU452

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]

Taxonomic identifier

107806 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Acyrthosiphon pisum)

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the MscS (TC 1.A.23) family. [View classification]

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 305	305	Uncharacterized MscS family protein BU452		PRO_0000110246
Regions
	Transmembrane	52 – 72	21	Helical; Potential
	Transmembrane	89 – 109	21	Helical; Potential
	Transmembrane	120 – 140	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P57527 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: 6F99B52D3EB9AA56	FASTA	305	34,129
	10 20 30 40 50 60 MLFIKIEIIA KTLLIINKKY TEIKMDELNV VNNINHAGTW LIRNQELLLR YTINLTSAII 70 80 90 100 110 120 ILVVGMFISK IISNGANQVL ITRNIDATIA GFLSALMRYI IITFTFIAAL GRIGVQTTSV 130 140 150 160 170 180 IAILGAAGMA IGLALQGSLS NFAAGVLLVT LRPLKTEEYV DLGSVSGTVL NIHIFYTTLR 190 200 210 220 230 240 TLDGKIVVVP NNKIISGNII NYSREPARRN EFIISVSYNS DIDLVIKILR SVIEKEERVI 250 260 270 280 290 300 KDKDIIVGLS ELAPSSLNFI VRCWSKNHDL NTVYWDLMAK FKKELDKNNI NIPFPQLDVH VYKKK

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: APS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000003 Genomic DNA. Translation: BAB13150.1.
RefSeq	NP_240264.2. NC_002528.1.
3D structure databases
ProteinModelPortal	P57527.
SMR	P57527. Positions 51-300.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAB13150; BAB13150; BAB13150.
GeneID	1109800.
KEGG	buc:BU452.
PATRIC	21244446. VBIBucAph127364_0462.
Phylogenomic databases
eggNOG	COG0668.
HOGENOM	HOG000110050.
KO	K03442.
OMA	NNINHAG.
ProtClustDB	CLSK380368.
Family and domain databases
InterPro	IPR010920. LSM_dom. IPR011066. MscC_channel_C. IPR006685. MscS_channel. IPR006686. MscS_channel_CS. IPR011014. MscS_channel_TM-2. IPR008910. TM_helix. [Graphical view]
Pfam	PF00924. MS_channel. 1 hit. PF05552. TM_helix. 1 hit. [Graphical view]
SUPFAM	SSF82689. MscC_channel_C. 1 hit. SSF82861. MscS_transmembr. 1 hit. SSF50182. Sm_like_riboprot. 1 hit.
PROSITE	PS01246. UPF0003. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y452_BUCAI

Accession

Primary (citable) accession number: P57527

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	May 1, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program