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P57525

- PGK_BUCAI

UniProt

P57525 - PGK_BUCAI

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Protein

Phosphoglycerate kinase

Gene
pgk, BU450
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei147 – 1471Substrate By similarity
Binding sitei198 – 1981ATP By similarity
Binding sitei314 – 3141ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi340 – 3434ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-450-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:BU450
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 390390Phosphoglycerate kinaseUniRule annotationPRO_0000145918Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliP57525.
SMRiP57525. Positions 2-386.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

P57525-1 [UniParc]FASTAAdd to Basket

« Hide

MTIRKMTELN ITEKRILIRS DLNVPIENGI IQSDARILAA LPTIELALQK    50
KAKVIIMSHL GRPKEGYYTK KYSLFPIFEY FKKKFNNTKI YFSNNFLDGI 100
KLNPGEIALL ENTRFNKGEL NNDEQLSKKY SDLCDIFVMD AFGSAHRMQS 150
STYGIGKFVK IACAGLLLIS EIDALKKALK KPKRPMVAIV GGSKVSTKFN 200
VLNKLSKIAD TIIVGGGIAN TFLAIDYKIG KSLYEPDFVF EAKKLRDKYN 250
IIVPIDSRVG KNFCKNEQAI IKSPDNIKED EEIMDFGDES IKKIISIITQ 300
SQTIMWNGPV GVFEFPNFRK GTEMIAKTIA NSNAFSIAGG GDTLSVIDMF 350
NIKNNISYIS TGGGAFLEFI EGKKLPAIQM LEENFKNKSK 390
Length:390
Mass (Da):43,653
Last modified:December 1, 2000 - v1
Checksum:i8535BD49D2C72C7A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB13148.1.
RefSeqiNP_240262.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB13148; BAB13148; BAB13148.
GeneIDi1109798.
KEGGibuc:BU450.
PATRICi21244442. VBIBucAph127364_0460.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB13148.1 .
RefSeqi NP_240262.1. NC_002528.1.

3D structure databases

ProteinModelPortali P57525.
SMRi P57525. Positions 2-386.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB13148 ; BAB13148 ; BAB13148 .
GeneIDi 1109798.
KEGGi buc:BU450.
PATRICi 21244442. VBIBucAph127364_0460.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci BAPH107806:GBZJ-450-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiPGK_BUCAI
AccessioniPrimary (citable) accession number: P57525
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: June 11, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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