P57524 (Y449_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UPF0056 membrane protein BU449

Gene names

Ordered Locus Names:

BU449

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]

Taxonomic identifier

107806 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Acyrthosiphon pisum)

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the UPF0056 (MarC) family.
Sequence caution	The sequence BAB13147.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	UPF0056 membrane protein BU449		PRO_0000156910
Regions
	Transmembrane	8 – 28	21	Helical; Potential
	Transmembrane	45 – 65	21	Helical; Potential
	Transmembrane	71 – 91	21	Helical; Potential
	Transmembrane	105 – 125	21	Helical; Potential
	Transmembrane	134 – 154	21	Helical; Potential
	Transmembrane	174 – 194	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P57524 [UniParc]. Last modified November 15, 2002. Version 2. Checksum: 86D841D9073C93DD	FASTA	196	22,056
	10 20 30 40 50 60 MTEIISTTIL LVLIMDPLGN LPIFMTILKH LDVKRRRIVV IREMIIALIV MLLFLFVGEK 70 80 90 100 110 120 ILIILNLKTE TVSISGGVIL FLIAIKMIFP SEDNNNEISS SEEPFLVPLA IPLVAGPSLL 130 140 150 160 170 180 ATLMLLSHQY LHHMFYLVGS LLISWFFTVI ILLSSSLFLK LFGSKGVNAL ERLMGLVLIM 190 LSTQMFLDGI RAWFKN

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: APS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000003 Genomic DNA. Translation: BAB13147.1. Different initiation.
RefSeq	NP_240261.2. NC_002528.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAB13147; BAB13147; BAB13147.
GeneID	1109797.
KEGG	buc:BU449.
PATRIC	21244440. VBIBucAph127364_0459.
Phylogenomic databases
eggNOG	COG2095.
HOGENOM	HOG000112970.
OMA	FLFAGEA.
ProtClustDB	PRK10739.
Family and domain databases
InterPro	IPR002771. Multi_antbiot-R_MarC. [Graphical view]
Pfam	PF01914. MarC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y449_BUCAI

Accession

Primary (citable) accession number: P57524

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	November 15, 2002
Last modified:	May 1, 2013
This is version 71 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program