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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei68L-glutamineUniRule annotation1
Binding sitei213L-glutamineUniRule annotation1
Binding sitei232ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi36 – 38ATPUniRule annotation3
Nucleotide bindingi42 – 48ATPUniRule annotation7
Nucleotide bindingi262 – 263ATPUniRule annotation2
Nucleotide bindingi270 – 272ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:BU415
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000001806 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001958271 – 571Glutamine--tRNA ligaseAdd BLAST571

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi107806.BU415.

Structurei

3D structure databases

ProteinModelPortaliP57490.
SMRiP57490.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi35 – 45"HIGH" regionUniRule annotationAdd BLAST11
Motifi269 – 273"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotationCurated

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 3 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

P57490-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTKKEIKNN NFICQIINKD LNENKNLSFY TRFPPEPNGY LHIGHAKSIC
60 70 80 90 100
LNFELASLYK GRCNLRFDDT NPLKENIKYI ESIKHDINWL GYKWHGNVRY
110 120 130 140 150
ASEYFLKLYQ YAQELIKKGL AYVDHLTKEQ IREYRGTLNT PGKNSPYRNR
160 170 180 190 200
TIQENIELFE KMKKGDFSEG EACLRAKINM SSSSIIMRDP VLYRIIFIKH
210 220 230 240 250
HQTQNKWCIY PMYDFAHCLS DSIEGITHSL CTLEFQDNKF LYNWILKNTS
260 270 280 290 300
VKHYPKQYEF SRLNLEFSIL SKRKIKILID KNIIEGWDDP RIPTLSALRR
310 320 330 340 350
KGYTPSSIKN FCQKIGVTKQ NNLIEFSMLE HCIRKELNQT AIRTMAILDP
360 370 380 390 400
IKIFLYNLDS NYKEEFIVPN HPNNPEMGTH KIIFTNTIYI DRSDFKEKYD
410 420 430 440 450
KKYKRLKLGE KIRLRYSYII HAEKIEKDEY GNISNIICYC DLNTLGRKPK
460 470 480 490 500
DNKNPAVIHW ISEKNTLSAE FKLYDQLFNI KNPEQQENFL LYINSKSLIK
510 520 530 540 550
KFGFIEKKIG EEIQKKISNN NIEIFFQFER IGYFCIDFID SKKNQLVFNR
560 570
TVGLRDTWDS KKIKTKNITN N
Length:571
Mass (Da):67,835
Last modified:December 1, 2000 - v1
Checksum:i1FCE69932D563D52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB13113.1.
RefSeqiNP_240227.1. NC_002528.1.
WP_010896103.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB13113; BAB13113; BAB13113.
GeneIDi1109763.
KEGGibuc:BU415.
PATRICifig|107806.10.peg.424.

Similar proteinsi

Entry informationi

Entry nameiSYQ_BUCAI
AccessioniPrimary (citable) accession number: P57490
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: August 30, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families