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P57459 (NUSA_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Transcription termination/antitermination protein NusA
Gene names
Name:nusA
Ordered Locus Names:BU378
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length496 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Participates in both transcription termination and antitermination By similarity. HAMAP-Rule MF_00945

Subunit structure

Monomer By similarity. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA By similarity. HAMAP-Rule MF_00945

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00945.

Sequence similarities

Belongs to the NusA family.

Contains 1 KH domain.

Contains 1 S1 motif domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 496496Transcription termination/antitermination protein NusA HAMAP-Rule MF_00945
PRO_0000181962

Regions

Domain135 – 20066S1 motif
Domain302 – 37069KH
Repeat364 – 414511 HAMAP-Rule MF_00945
Repeat440 – 490512 HAMAP-Rule MF_00945
Region364 – 4901272 X 51 AA approximate repeats By similarity

Sequences

Sequence LengthMass (Da)Tools
P57459 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 17878203D5D4164E

FASTA49655,995
        10         20         30         40         50         60 
MNKEILAVVE AVSNEKSLPR EKIFEALEMA LATATKKKHE QEIDIRVSIN RKTGGFTTFR 

        70         80         90        100        110        120 
RWMVVETVTQ PTREITLEAA CFDGEKVYLN DYIEEQIESV DFDRITTQTA KQVIVQKVRE 

       130        140        150        160        170        180 
AERAMLVEQF RKYTGQIITG IVKKINRDNI MLDLGNNAEA LILREGMLPR ENFRPGDRIR 

       190        200        210        220        230        240 
GILYGVYPEA RGAQLFISRS KTEMLTELFR IEVPEIGEEV IEIKAAARDP GSRAKIAVKT 

       250        260        270        280        290        300 
NDKRIDPVGA CVGMRGARVQ AVSSELCGER IDIILWDDNP AQFVINAMAP ADVASIVVDE 

       310        320        330        340        350        360 
DCHTMDIAVD INNLAQAIGR NGQNVRLASQ ISGWELNVMT TEDLHSKHKE EAHTAFNFFK 

       370        380        390        400        410        420 
KNLNINENII KILVKEGFSS LEELAYIPFN ELLEVKNLTE DQAKKVREGA KSKLLLMESD 

       430        440        450        460        470        480 
KNKMIIQERK TEKELLKING MNAVLALQLA EKNIFTIEEL ADQGIDDLTD IKNLNSEQAG 

       490 
LLIMTARNIC WFSSKV 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB13082.1.
RefSeqNP_240196.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57459.
SMRP57459. Positions 430-494.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP57459.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB13082; BAB13082; BAB13082.
GeneID1109732.
KEGGbuc:BU378.
PATRIC21244294. VBIBucAph127364_0392.

Phylogenomic databases

eggNOGCOG0195.
HOGENOMHOG000006394.
KOK02600.
OMADVFTKHL.
OrthoDBEOG6NSGHW.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-378-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
3.30.1480.10. 1 hit.
3.30.300.20. 2 hits.
HAMAPMF_00945_B. NusA_B.
InterProIPR010995. DNA_repair_Rad51/TF_NusA_a-hlx.
IPR004087. KH_dom.
IPR015946. KH_dom-like_a/b.
IPR025249. KH_dom_NusA-like.
IPR004088. KH_dom_type_1.
IPR009019. KH_prok-type.
IPR012340. NA-bd_OB-fold.
IPR028620. NusA.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR022967. RNA-binding_domain_S1.
IPR013735. TF_NusA_N.
IPR010214. Tscrpt_termin_fac_NusA_C_rpt.
IPR010213. Tscrpt_termination_fac_NusA.
[Graphical view]
PfamPF13184. KH_5. 1 hit.
PF08529. NusA_N. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTSM00322. KH. 2 hits.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMSSF47794. SSF47794. 2 hits.
SSF50249. SSF50249. 1 hit.
SSF54814. SSF54814. 2 hits.
SSF69705. SSF69705. 1 hit.
TIGRFAMsTIGR01953. NusA. 1 hit.
TIGR01954. nusA_Cterm_rpt. 2 hits.
PROSITEPS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNUSA_BUCAI
AccessionPrimary (citable) accession number: P57459
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: June 11, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names