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P57442 (PNCB_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:BU361
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205823

Sequences

Sequence LengthMass (Da)Tools
P57442 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 09A735641222EE19

FASTA39946,751
        10         20         30         40         50         60 
MKRYDYPIVK TLLDTDAYKL HMQQAVFYHY KNVNVVAEFL CRGDNFLGCY ANILLDQISM 

        70         80         90        100        110        120 
MRSLSLSHEE YVYMTSFPFF KKEYLHWLKK FRYNVSQVKI NSYQGRLHIR ISGLWKEVIL 

       130        140        150        160        170        180 
WEVPILALIS EVFHGNFSPE ITSQSALQYL DIKLKKFFNR TKYIDLSHLK IVDFGTRRRF 

       190        200        210        220        230        240 
SYDVQYSIVK RLKESFPFLI GSSNYHIARI LKIKPVGTQA HEWFQAHQQI GSNLKNSQIL 

       250        260        270        280        290        300 
ALQKWLYQYK NHLGIALTDS ITMDAFLDDF NLHFASFYQG IRHDSGDPVK WGEKALKHYE 

       310        320        330        340        350        360 
KLGIDPCTKT LLFSDNLDFK KIISLYKKFH KKINVIFGIG TKLTCDIPYV KPLNIVIKLV 

       370        380        390 
ECNGKPVAKI SDSPGKTFCL DRIFLKNLCQ VFNVSLKNR 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB13065.1.
RefSeqNP_240179.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57442.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB13065; BAB13065; BAB13065.
GeneID1110057.
KEGGbuc:BU361.
PATRIC21244258. VBIBucAph127364_0374.

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-361-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_BUCAI
AccessionPrimary (citable) accession number: P57442
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 14, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names