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P57430

- RLUC_BUCAI

UniProt

P57430 - RLUC_BUCAI

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Protein
Ribosomal large subunit pseudouridine synthase C
Gene
rluC, BU348
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA By similarity.

Catalytic activityi

23S rRNA uridine(955)/uridine(2504)/uridine(2580) = 23S rRNA pseudouridine(955)/pseudouridine(2504)/pseudouridine(2580).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei143 – 1431 By similarity

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
  2. pseudouridine synthase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
  2. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-348-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal large subunit pseudouridine synthase C (EC:5.4.99.24)
Alternative name(s):
23S rRNA pseudouridine(955/2504/2580) synthase
rRNA pseudouridylate synthase C
rRNA-uridine isomerase C
Gene namesi
Name:rluC
Ordered Locus Names:BU348
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 314314Ribosomal large subunit pseudouridine synthase C
PRO_0000162664Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP57430.
SMRiP57430. Positions 92-312.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 8465S4 RNA-binding
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0564.
HOGENOMiHOG000275914.
KOiK06179.
OMAiKKQVNAP.
OrthoDBiEOG6P070X.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57430-1 [UniParc]FASTAAdd to Basket

« Hide

MTHKILPISI IYINKEMLNQ RIDNFMRSKF KSVPKSMIYR IIRTGKIRIN    50
KKRIKPHYKL KIGDILKIPP IKILCDIKNT FFPLNHSTNL LNRILYEDSH 100
LLIINKPSGI AVHGGSGLNF GVIEYFRKLR PLNKFLELVH RIDRDTSGVL 150
ILAKKRTSLV SLHEQLREKK IKKEYIALVH GLWPDHIKKI SEPLLKIQFK 200
NKQKMVLIDK KGKPSETYFQ IKKKFSSSTL LSIIPKTGRT HQIRVHALHA 250
GHPIFFDKRY GKNDLDADIK NNHKINRLLL HSSGVHFIHP KNGNKIYIKA 300
PLDIDFQNYL NTII 314
Length:314
Mass (Da):36,614
Last modified:December 1, 2000 - v1
Checksum:i4B0FC4D2FD085B08
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB13053.1.
RefSeqiNP_240167.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB13053; BAB13053; BAB13053.
GeneIDi1110044.
KEGGibuc:BU348.
PATRICi21244230. VBIBucAph127364_0360.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB13053.1 .
RefSeqi NP_240167.1. NC_002528.1.

3D structure databases

ProteinModelPortali P57430.
SMRi P57430. Positions 92-312.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB13053 ; BAB13053 ; BAB13053 .
GeneIDi 1110044.
KEGGi buc:BU348.
PATRICi 21244230. VBIBucAph127364_0360.

Phylogenomic databases

eggNOGi COG0564.
HOGENOMi HOG000275914.
KOi K06179.
OMAi KKQVNAP.
OrthoDBi EOG6P070X.

Enzyme and pathway databases

BioCyci BAPH107806:GBZJ-348-MONOMER.

Family and domain databases

Gene3Di 3.10.290.10. 1 hit.
InterProi IPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view ]
Pfami PF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view ]
SMARTi SM00363. S4. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
TIGRFAMsi TIGR00005. rluA_subfam. 1 hit.
PROSITEi PS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiRLUC_BUCAI
AccessioniPrimary (citable) accession number: P57430
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 14, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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