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Protein

Ribosomal large subunit pseudouridine synthase C

Gene

rluC

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.By similarity

Catalytic activityi

23S rRNA uridine(955)/uridine(2504)/uridine(2580) = 23S rRNA pseudouridine(955)/pseudouridine(2504)/pseudouridine(2580).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei143By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, RNA-binding
Biological processrRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal large subunit pseudouridine synthase C (EC:5.4.99.24)
Alternative name(s):
23S rRNA pseudouridine(955/2504/2580) synthase
rRNA pseudouridylate synthase C
rRNA-uridine isomerase C
Gene namesi
Name:rluC
Ordered Locus Names:BU348
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000001806 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001626641 – 314Ribosomal large subunit pseudouridine synthase CAdd BLAST314

Proteomic databases

PRIDEiP57430

Interactioni

Protein-protein interaction databases

STRINGi107806.BU348

Structurei

3D structure databases

ProteinModelPortaliP57430
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 84S4 RNA-bindingPROSITE-ProRule annotationAdd BLAST65

Sequence similaritiesi

Belongs to the pseudouridine synthase RluA family.Curated

Phylogenomic databases

eggNOGiENOG4105EI2 Bacteria
COG0564 LUCA
HOGENOMiHOG000275914
KOiK06179
OMAiPKTHVYR

Family and domain databases

CDDicd02869 PseudoU_synth_RluCD_like, 1 hit
cd00165 S4, 1 hit
Gene3Di3.10.290.10, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR006225 PsdUridine_synth_RluC/D
IPR006224 PsdUridine_synth_RluC/D_CS
IPR006145 PsdUridine_synth_RsuA/RluD
IPR002942 S4_RNA-bd
IPR036986 S4_RNA-bd_sf
PfamiView protein in Pfam
PF00849 PseudoU_synth_2, 1 hit
PF01479 S4, 1 hit
SMARTiView protein in SMART
SM00363 S4, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00005 rluA_subfam, 1 hit
PROSITEiView protein in PROSITE
PS01129 PSI_RLU, 1 hit
PS50889 S4, 1 hit

Sequencei

Sequence statusi: Complete.

P57430-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHKILPISI IYINKEMLNQ RIDNFMRSKF KSVPKSMIYR IIRTGKIRIN
60 70 80 90 100
KKRIKPHYKL KIGDILKIPP IKILCDIKNT FFPLNHSTNL LNRILYEDSH
110 120 130 140 150
LLIINKPSGI AVHGGSGLNF GVIEYFRKLR PLNKFLELVH RIDRDTSGVL
160 170 180 190 200
ILAKKRTSLV SLHEQLREKK IKKEYIALVH GLWPDHIKKI SEPLLKIQFK
210 220 230 240 250
NKQKMVLIDK KGKPSETYFQ IKKKFSSSTL LSIIPKTGRT HQIRVHALHA
260 270 280 290 300
GHPIFFDKRY GKNDLDADIK NNHKINRLLL HSSGVHFIHP KNGNKIYIKA
310
PLDIDFQNYL NTII
Length:314
Mass (Da):36,614
Last modified:December 1, 2000 - v1
Checksum:i4B0FC4D2FD085B08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA Translation: BAB13053.1
RefSeqiNP_240167.1, NC_002528.1
WP_009874303.1, NC_002528.1

Genome annotation databases

EnsemblBacteriaiBAB13053; BAB13053; BAB13053
GeneIDi1110044
KEGGibuc:BU348
PATRICifig|107806.10.peg.360

Similar proteinsi

Entry informationi

Entry nameiRLUC_BUCAI
AccessioniPrimary (citable) accession number: P57430
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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