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P57413 (RSMC_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase C

EC=2.1.1.172
Alternative name(s):
16S rRNA m2G1207 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RsmC
Gene names
Name:rsmC
Ordered Locus Names:BU328
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length338 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle By similarity. HAMAP-Rule MF_01862

Catalytic activity

S-adenosyl-L-methionine + guanine(1207) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(1207) in 16S rRNA. HAMAP-Rule MF_01862

Subunit structure

Monomer By similarity. HAMAP-Rule MF_01862

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_01862.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmC family.

Sequence caution

The sequence BAB13036.1 differs from that shown. Reason: Frameshift at position 57.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function16S rRNA (guanine(1207)-N(2))-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

nucleic acid binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 338338Ribosomal RNA small subunit methyltransferase C HAMAP-Rule MF_01862
PRO_0000097487

Sequences

Sequence LengthMass (Da)Tools
P57413 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: E43516DDD22FA014

FASTA33839,105
        10         20         30         40         50         60 
MLLSKNSQLI LRHRKKFKTK KVFFSGNIQD DFPLSLSTMR TKINFHKYND CIDFKKKIMN 

        70         80         90        100        110        120 
NNIVHNNLLI SQEMIQNCDV IIYYWPKDKS EAKFQLMNII SCSPINTEIF IVGNNSSGVK 

       130        140        150        160        170        180 
SAPLMLKKWI ELEKIDSAKH SILISGLIKK KAIFVLEDFF KTHLWKNLII KSLPGVFGHK 

       190        200        210        220        230        240 
KIDSGSKLLA STFSNRITGK VLDIGCGTGF LSASLLYFSP DAILTLVDNN MYALKCSQYT 

       250        260        270        280        290        300 
LNSNKFNGKI VYSNLYSNVF KKFDLIISNP PFHNDLQINF NIIEKMICGA KKYLTKTGEL 

       310        320        330 
RFVTSRFINC HFLLNKFFQK YYVIKETSQY KVYQAFYK 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB13036.1. Frameshift.
RefSeqNP_240150.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57413.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB13036; BAB13036; BAB13036.
GeneID1110027.
KEGGbuc:BU328.
PATRIC21244186. VBIBucAph127364_0341.

Phylogenomic databases

eggNOGCOG2813.
HOGENOMHOG000218308.
KOK00564.
OMARHCQLWQ.
OrthoDBEOG67X1ZC.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-328-MONOMER.

Family and domain databases

Gene3D3.40.50.150. 1 hit.
HAMAPMF_01862. 16SrRNA_methyltr_C.
InterProIPR002052. DNA_methylase_N6_adenine_CS.
IPR013675. Mtase_sm_N.
IPR023543. rRNA_ssu_MeTfrase_C.
IPR029063. SAM-dependent_MTases-like.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamPF05175. MTS. 1 hit.
PF08468. MTS_N. 1 hit.
[Graphical view]
SUPFAMSSF53335. SSF53335. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRSMC_BUCAI
AccessionPrimary (citable) accession number: P57413
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: June 11, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names