P57403 (ZNUC_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Zinc import ATP-binding protein ZnuC
EC=3.6.3.-

Gene names

Name:	znuC
Ordered Locus Names:	BU318

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]

Taxonomic identifier

107806 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Acyrthosiphon pisum)

Protein attributes

Sequence length	238 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system By similarity.
Subunit structure	The complex is composed of two ATP-binding proteins (ZnuC), two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA) Potential.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. [View classification] Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Ion transport Transport Zinc transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding Zinc
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro zinc transporting ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 238	238	Zinc import ATP-binding protein ZnuC		PRO_0000093127
Regions
	Domain	5 – 220	216	ABC transporter
	Nucleotide binding	37 – 44	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P57403 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: FDDC7CF7BBD3CF9A	FASTA	238	26,814
	10 20 30 40 50 60 MFEFVKLKNV CVNLSHRSIL TDISLSLISN RVLTLIGPNG AGKSTLVRII LGLIKPNSGT 70 80 90 100 110 120 IIRSNNLSVG YVPQKLHLNT LLPITVERFM KLSRKTNNIK IEEMLKRVKA ESLKFCQLQK 130 140 150 160 170 180 LSGGEMQRIL FAKALLNNPN LLVLDEPTQG VDVMGQLALY KLINEIRHEL QCAILIVSHD 190 200 210 220 230 LNFVMAKTDD VICLNNHICC SGTPETVCNN LEFISIFGLK RVQELAIYHH NHNHIHNF

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: APS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000003 Genomic DNA. Translation: BAB13026.1.
RefSeq	NP_240140.1. NC_002528.1.
3D structure databases
ProteinModelPortal	P57403.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAB13026; BAB13026; BAB13026.
GeneID	1110017.
KEGG	buc:BU318.
PATRIC	21244164. VBIBucAph127364_0330.
Phylogenomic databases
eggNOG	COG1121.
KO	K09817.
OMA	ENLAFAI.
ProtClustDB	CLSK315881.
Enzyme and pathway databases
BioCyc	BAPH107806:GBZJ-318-MONOMER.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017882. ABC_transptr_Zn_ATP-bd_ZnuC. IPR027417. P-loop_NTPase. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF52540. SSF52540. 1 hit.
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. PS51298. ZNUC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ZNUC_BUCAI

Accession

Primary (citable) accession number: P57403

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	May 29, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program