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P57396 (AROA_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:BU311
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4274273-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_0000088235

Sequences

Sequence LengthMass (Da)Tools
P57396 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 2FA4A2CFA8701285

FASTA42746,786
        10         20         30         40         50         60 
MQNSLDLKPI SHVNGTVCLP GSKSISNRVL LLSSIAKGTT CLTNLLNSHD TQHMLNALKK 

        70         80         90        100        110        120 
LGVRYNLSDD KKTCHVQGIG GPFHLSEAIS LYLGNAGTAI RPLLSVLSLH KNNILLNGDD 

       130        140        150        160        170        180 
RMHERPIGDL VDALIQGGAV IEYKKNKGYP PICTKGGFLG GSIFLNGNIS SQFLTSLLIS 

       190        200        210        220        230        240 
TPLALKDTTI FIKGNLVSKP YIDITLNLIK IFGVNIEHDS YNVFYIKGKQ QYKTPGKYTI 

       250        260        270        280        290        300 
EGDASSASYF LAAAAIKGGS IKVTGVGKKS IQGDIEFANI LEKMGATIFW EDYSITCTRN 

       310        320        330        340        350        360 
KLNAIDLDMN HIPDAAMTVA ILALFSKGTT IIRNIYNWRV KETDRLSAMT IELRKIGAIV 

       370        380        390        400        410        420 
EEGRDFLSIS PPIFFQYSSI ETYNDHRMAM CFSLISLSGV GVNILNPNCI SKTFPSYFKD 


FLSISKI

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed: 10993077] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000003 Genomic DNA. Translation: BAB13019.1.
RefSeqNP_240133.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57396.
SMRP57396. Positions 4-426.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBUCT00000003301; EBBUCP00000003077; EBBUCG00000003301.
GeneID1110010.
GenomeReviewsGene locus BU311 in contig BA000003_GR.
KEGGbuc:BU311.
PATRIC21244150. VBIBucAph127364_0323.

Phylogenomic databases

GeneTreeEBGT00050000008084.
HOGENOMHBG646626.
OMAGADIEWG.
PhylomeDBP57396.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycBSP107806:BU311-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_BUCAI
AccessionPrimary (citable) accession number: P57396
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: January 25, 2012
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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