Reviewed, UniProtKB/Swiss-Prot P57380 (6PGL_BUCAI)

Names and origin

Protein names

Recommended name:
    6-phosphogluconolactonase
      Short name=6-P-gluconolactonase
    EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	BU293

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]

Taxonomic identifier

118099 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 334	334	6-phosphogluconolactonase HAMAP MF_01605		PRO_0000171128

Sequences

	Sequence		Length	Mass (Da)
	P57380-1 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: 917BD56378A50908	FASTA	334	38,947
	10 20 30 40 50 60 MKQVVYIANS ESKNIEVWNL CKSGKMNLIQ KIETDGKIQP INIIQKRNLL YAGIFPDNKI 70 80 90 100 110 120 ITYSINHNGF LEKKNESNIP GKANYISFDK KKEFLFCSSY HSNFISVSPL NKFGIPQNPI 130 140 150 160 170 180 QIIYNIEGCH AAKMNYKYNI LFVISLKEDC IYLYYLTDFG ILKSTEQNIL HTQKKSGPRH 190 200 210 220 230 240 IIFHPNQDFI YTINELNGTI DVWKIYKKNN VIKVKNIQNI HVLKNRFLKD YWCSDIHITS 250 260 270 280 290 300 CGRFLYACDR FFNIISLFHI NQNDNKLVFF KSYDTEEQPR SFNINSHNTH LIVAGEKSNT 310 320 330 FIIYSISNST GELKKINVYS TGQRPVWILI HALC

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tokyo 1998.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000003 Genomic DNA. Translation: BAB13003.1.
RefSeq	NP_240117.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1109992.
GenomeReviews	Gene locus BU293 in contig BA000003_GR.
KEGG	buc:BU293.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P57380.
OMA	AYVINEL.
Enzyme and pathway databases
BioCyc	BSP107806:BU293-MON.
Family and domain databases
HAMAP	MF_01605. [Tree]
InterPro	IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_BUCAI

Accession

Primary (citable) accession number: P57380

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	November 3, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)