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P57380

- 6PGL_BUCAI

UniProt

P57380 - 6PGL_BUCAI

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Protein

6-phosphogluconolactonase

Gene
pgl, BU293
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.UniRule annotation

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-293-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6-P-gluconolactonase
Gene namesi
Name:pgl
Ordered Locus Names:BU293
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3343346-phosphogluconolactonaseUniRule annotationPRO_0000171128Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP57380.

Family & Domainsi

Sequence similaritiesi

Belongs to the cycloisomerase 2 family.

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000257418.
KOiK07404.
OMAiYVSVYAI.
OrthoDBiEOG615VK7.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_01605. 6P_gluconolactonase.
InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57380-1 [UniParc]FASTAAdd to Basket

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MKQVVYIANS ESKNIEVWNL CKSGKMNLIQ KIETDGKIQP INIIQKRNLL    50
YAGIFPDNKI ITYSINHNGF LEKKNESNIP GKANYISFDK KKEFLFCSSY 100
HSNFISVSPL NKFGIPQNPI QIIYNIEGCH AAKMNYKYNI LFVISLKEDC 150
IYLYYLTDFG ILKSTEQNIL HTQKKSGPRH IIFHPNQDFI YTINELNGTI 200
DVWKIYKKNN VIKVKNIQNI HVLKNRFLKD YWCSDIHITS CGRFLYACDR 250
FFNIISLFHI NQNDNKLVFF KSYDTEEQPR SFNINSHNTH LIVAGEKSNT 300
FIIYSISNST GELKKINVYS TGQRPVWILI HALC 334
Length:334
Mass (Da):38,947
Last modified:December 1, 2000 - v1
Checksum:i917BD56378A50908
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB13003.1.
RefSeqiNP_240117.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB13003; BAB13003; BAB13003.
GeneIDi1109992.
KEGGibuc:BU293.
PATRICi21244110. VBIBucAph127364_0303.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB13003.1 .
RefSeqi NP_240117.1. NC_002528.1.

3D structure databases

ProteinModelPortali P57380.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB13003 ; BAB13003 ; BAB13003 .
GeneIDi 1109992.
KEGGi buc:BU293.
PATRICi 21244110. VBIBucAph127364_0303.

Phylogenomic databases

eggNOGi COG2706.
HOGENOMi HOG000257418.
KOi K07404.
OMAi YVSVYAI.
OrthoDBi EOG615VK7.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci BAPH107806:GBZJ-293-MONOMER.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
HAMAPi MF_01605. 6P_gluconolactonase.
InterProi IPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view ]
Pfami PF10282. Lactonase. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry namei6PGL_BUCAI
AccessioniPrimary (citable) accession number: P57380
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 14, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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