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P57380

- 6PGL_BUCAI

UniProt

P57380 - 6PGL_BUCAI

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Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.UniRule annotation

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-293-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonaseUniRule annotation (EC:3.1.1.31UniRule annotation)
Short name:
6-P-gluconolactonaseUniRule annotation
Gene namesi
Name:pglUniRule annotation
Ordered Locus Names:BU293
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3343346-phosphogluconolactonasePRO_0000171128Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP57380.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cycloisomerase 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000257418.
KOiK07404.
OMAiYVSVYAI.
OrthoDBiEOG615VK7.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_01605. 6P_gluconolactonase.
InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57380-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKQVVYIANS ESKNIEVWNL CKSGKMNLIQ KIETDGKIQP INIIQKRNLL
60 70 80 90 100
YAGIFPDNKI ITYSINHNGF LEKKNESNIP GKANYISFDK KKEFLFCSSY
110 120 130 140 150
HSNFISVSPL NKFGIPQNPI QIIYNIEGCH AAKMNYKYNI LFVISLKEDC
160 170 180 190 200
IYLYYLTDFG ILKSTEQNIL HTQKKSGPRH IIFHPNQDFI YTINELNGTI
210 220 230 240 250
DVWKIYKKNN VIKVKNIQNI HVLKNRFLKD YWCSDIHITS CGRFLYACDR
260 270 280 290 300
FFNIISLFHI NQNDNKLVFF KSYDTEEQPR SFNINSHNTH LIVAGEKSNT
310 320 330
FIIYSISNST GELKKINVYS TGQRPVWILI HALC
Length:334
Mass (Da):38,947
Last modified:December 1, 2000 - v1
Checksum:i917BD56378A50908
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB13003.1.
RefSeqiNP_240117.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB13003; BAB13003; BAB13003.
GeneIDi1109992.
KEGGibuc:BU293.
PATRICi21244110. VBIBucAph127364_0303.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB13003.1 .
RefSeqi NP_240117.1. NC_002528.1.

3D structure databases

ProteinModelPortali P57380.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB13003 ; BAB13003 ; BAB13003 .
GeneIDi 1109992.
KEGGi buc:BU293.
PATRICi 21244110. VBIBucAph127364_0303.

Phylogenomic databases

eggNOGi COG2706.
HOGENOMi HOG000257418.
KOi K07404.
OMAi YVSVYAI.
OrthoDBi EOG615VK7.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci BAPH107806:GBZJ-293-MONOMER.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
HAMAPi MF_01605. 6P_gluconolactonase.
InterProi IPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view ]
Pfami PF10282. Lactonase. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry namei6PGL_BUCAI
AccessioniPrimary (citable) accession number: P57380
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: October 1, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3