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P57380

- 6PGL_BUCAI

UniProt

P57380 - 6PGL_BUCAI

Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Dec 2000)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.UniRule annotation

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Glucose metabolism

    Enzyme and pathway databases

    BioCyciBAPH107806:GBZJ-293-MONOMER.
    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phosphogluconolactonaseUniRule annotation (EC:3.1.1.31UniRule annotation)
    Short name:
    6-P-gluconolactonaseUniRule annotation
    Gene namesi
    Name:pglUniRule annotation
    Ordered Locus Names:BU293
    OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
    Taxonomic identifieri107806 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000001806: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 3343346-phosphogluconolactonasePRO_0000171128Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP57380.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cycloisomerase 2 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2706.
    HOGENOMiHOG000257418.
    KOiK07404.
    OMAiYVSVYAI.
    OrthoDBiEOG615VK7.

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    HAMAPiMF_01605. 6P_gluconolactonase.
    InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
    IPR019405. Lactonase_7-beta_prop.
    IPR015943. WD40/YVTN_repeat-like_dom.
    [Graphical view]
    PfamiPF10282. Lactonase. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P57380-1 [UniParc]FASTAAdd to Basket

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    MKQVVYIANS ESKNIEVWNL CKSGKMNLIQ KIETDGKIQP INIIQKRNLL    50
    YAGIFPDNKI ITYSINHNGF LEKKNESNIP GKANYISFDK KKEFLFCSSY 100
    HSNFISVSPL NKFGIPQNPI QIIYNIEGCH AAKMNYKYNI LFVISLKEDC 150
    IYLYYLTDFG ILKSTEQNIL HTQKKSGPRH IIFHPNQDFI YTINELNGTI 200
    DVWKIYKKNN VIKVKNIQNI HVLKNRFLKD YWCSDIHITS CGRFLYACDR 250
    FFNIISLFHI NQNDNKLVFF KSYDTEEQPR SFNINSHNTH LIVAGEKSNT 300
    FIIYSISNST GELKKINVYS TGQRPVWILI HALC 334
    Length:334
    Mass (Da):38,947
    Last modified:December 1, 2000 - v1
    Checksum:i917BD56378A50908
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB13003.1.
    RefSeqiNP_240117.1. NC_002528.1.

    Genome annotation databases

    EnsemblBacteriaiBAB13003; BAB13003; BAB13003.
    GeneIDi1109992.
    KEGGibuc:BU293.
    PATRICi21244110. VBIBucAph127364_0303.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB13003.1 .
    RefSeqi NP_240117.1. NC_002528.1.

    3D structure databases

    ProteinModelPortali P57380.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB13003 ; BAB13003 ; BAB13003 .
    GeneIDi 1109992.
    KEGGi buc:BU293.
    PATRICi 21244110. VBIBucAph127364_0303.

    Phylogenomic databases

    eggNOGi COG2706.
    HOGENOMi HOG000257418.
    KOi K07404.
    OMAi YVSVYAI.
    OrthoDBi EOG615VK7.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .
    BioCyci BAPH107806:GBZJ-293-MONOMER.

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    HAMAPi MF_01605. 6P_gluconolactonase.
    InterProi IPR022528. 6-phosphogluconolactonase_YbhE.
    IPR019405. Lactonase_7-beta_prop.
    IPR015943. WD40/YVTN_repeat-like_dom.
    [Graphical view ]
    Pfami PF10282. Lactonase. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
      Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
      Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: APS.

    Entry informationi

    Entry namei6PGL_BUCAI
    AccessioniPrimary (citable) accession number: P57380
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: December 1, 2000
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
      Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3