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P57360 (HNS_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-binding protein H-NS homolog
Gene names
Name:hns
Ordered Locus Names:BU272
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length135 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Binds tightly to ds-DNA, increases its thermal stability and inhibits transcription By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the histone-like protein H-NS family.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   LigandDNA-binding
   Molecular functionRepressor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintracellular

Inferred from electronic annotation. Source: InterPro

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 135135DNA-binding protein H-NS homolog
PRO_0000168502

Sequences

Sequence LengthMass (Da)Tools
P57360 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 2D46B9A2E752BD68

FASTA13516,005
        10         20         30         40         50         60 
MNEILKILNN IRTLRVHSRE CSLEILEEIL EKFKVVINER KKEEKKIKEE IAQRAIKLKK 

        70         80         90        100        110        120 
YREMLIADGI NPNELLTKTN SIKSSEKRKR PKRPAKYKYI NKNGDFKTWT GQGRTPSVIK 

       130 
NAILERKKIL EDFLL 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB12982.1.
RefSeqNP_240096.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57360.
SMRP57360. Positions 2-44, 92-135.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP57360.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB12982; BAB12982; BAB12982.
GeneID1109711.
KEGGbuc:BU272.
PATRIC21244068. VBIBucAph127364_0282.

Phylogenomic databases

eggNOGCOG2916.
HOGENOMHOG000218473.
KOK03746.
OMANGENKTW.
OrthoDBEOG6NPM97.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-272-MONOMER.

Family and domain databases

Gene3D1.10.287.1050. 1 hit.
4.10.430.10. 1 hit.
InterProIPR027444. H-NS_C_dom.
IPR001801. Histone_HNS.
IPR027454. Histone_HNS_oligo_dom.
[Graphical view]
PfamPF00816. Histone_HNS. 1 hit.
[Graphical view]
PIRSFPIRSF002096. HnS. 1 hit.
SMARTSM00528. HNS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHNS_BUCAI
AccessionPrimary (citable) accession number: P57360
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 14, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names