Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA-binding protein H-NS homolog

Gene

hns

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds tightly to ds-DNA, increases its thermal stability and inhibits transcription.By similarity

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-272-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-binding protein H-NS homolog
Gene namesi
Name:hns
Ordered Locus Names:BU272
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 135135DNA-binding protein H-NS homologPRO_0000168502Add
BLAST

Proteomic databases

PRIDEiP57360.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP57360.
SMRiP57360. Positions 2-44, 92-135.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histone-like protein H-NS family.Curated

Phylogenomic databases

eggNOGiCOG2916.
HOGENOMiHOG000218473.
KOiK03746.
OMAiLQQYRDM.
OrthoDBiEOG6NPM97.

Family and domain databases

Gene3Di1.10.287.1050. 1 hit.
4.10.430.10. 1 hit.
InterProiIPR027444. H-NS_C_dom.
IPR001801. Histone_HNS.
IPR027454. Histone_HNS_oligo_dom.
[Graphical view]
PfamiPF00816. Histone_HNS. 1 hit.
[Graphical view]
PIRSFiPIRSF002096. HnS. 1 hit.
SMARTiSM00528. HNS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57360-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNEILKILNN IRTLRVHSRE CSLEILEEIL EKFKVVINER KKEEKKIKEE
60 70 80 90 100
IAQRAIKLKK YREMLIADGI NPNELLTKTN SIKSSEKRKR PKRPAKYKYI
110 120 130
NKNGDFKTWT GQGRTPSVIK NAILERKKIL EDFLL
Length:135
Mass (Da):16,005
Last modified:December 1, 2000 - v1
Checksum:i2D46B9A2E752BD68
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB12982.1.
RefSeqiNP_240096.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB12982; BAB12982; BAB12982.
GeneIDi1109711.
KEGGibuc:BU272.
PATRICi21244068. VBIBucAph127364_0282.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB12982.1.
RefSeqiNP_240096.1. NC_002528.1.

3D structure databases

ProteinModelPortaliP57360.
SMRiP57360. Positions 2-44, 92-135.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP57360.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB12982; BAB12982; BAB12982.
GeneIDi1109711.
KEGGibuc:BU272.
PATRICi21244068. VBIBucAph127364_0282.

Phylogenomic databases

eggNOGiCOG2916.
HOGENOMiHOG000218473.
KOiK03746.
OMAiLQQYRDM.
OrthoDBiEOG6NPM97.

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-272-MONOMER.

Family and domain databases

Gene3Di1.10.287.1050. 1 hit.
4.10.430.10. 1 hit.
InterProiIPR027444. H-NS_C_dom.
IPR001801. Histone_HNS.
IPR027454. Histone_HNS_oligo_dom.
[Graphical view]
PfamiPF00816. Histone_HNS. 1 hit.
[Graphical view]
PIRSFiPIRSF002096. HnS. 1 hit.
SMARTiSM00528. HNS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiHNS_BUCAI
AccessioniPrimary (citable) accession number: P57360
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: January 7, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.