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P57360

- HNS_BUCAI

UniProt

P57360 - HNS_BUCAI

Protein

DNA-binding protein H-NS homolog

Gene

hns

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Dec 2000)
      Previous versions | rss
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    Functioni

    Binds tightly to ds-DNA, increases its thermal stability and inhibits transcription.By similarity

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Repressor

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciBAPH107806:GBZJ-272-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA-binding protein H-NS homolog
    Gene namesi
    Name:hns
    Ordered Locus Names:BU272
    OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
    Taxonomic identifieri107806 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000001806: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 135135DNA-binding protein H-NS homologPRO_0000168502Add
    BLAST

    Proteomic databases

    PRIDEiP57360.

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP57360.
    SMRiP57360. Positions 2-44, 92-135.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone-like protein H-NS family.Curated

    Phylogenomic databases

    eggNOGiCOG2916.
    HOGENOMiHOG000218473.
    KOiK03746.
    OMAiNGENKTW.
    OrthoDBiEOG6NPM97.

    Family and domain databases

    Gene3Di1.10.287.1050. 1 hit.
    4.10.430.10. 1 hit.
    InterProiIPR027444. H-NS_C_dom.
    IPR001801. Histone_HNS.
    IPR027454. Histone_HNS_oligo_dom.
    [Graphical view]
    PfamiPF00816. Histone_HNS. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002096. HnS. 1 hit.
    SMARTiSM00528. HNS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P57360-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNEILKILNN IRTLRVHSRE CSLEILEEIL EKFKVVINER KKEEKKIKEE    50
    IAQRAIKLKK YREMLIADGI NPNELLTKTN SIKSSEKRKR PKRPAKYKYI 100
    NKNGDFKTWT GQGRTPSVIK NAILERKKIL EDFLL 135
    Length:135
    Mass (Da):16,005
    Last modified:December 1, 2000 - v1
    Checksum:i2D46B9A2E752BD68
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB12982.1.
    RefSeqiNP_240096.1. NC_002528.1.

    Genome annotation databases

    EnsemblBacteriaiBAB12982; BAB12982; BAB12982.
    GeneIDi1109711.
    KEGGibuc:BU272.
    PATRICi21244068. VBIBucAph127364_0282.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB12982.1 .
    RefSeqi NP_240096.1. NC_002528.1.

    3D structure databases

    ProteinModelPortali P57360.
    SMRi P57360. Positions 2-44, 92-135.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P57360.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB12982 ; BAB12982 ; BAB12982 .
    GeneIDi 1109711.
    KEGGi buc:BU272.
    PATRICi 21244068. VBIBucAph127364_0282.

    Phylogenomic databases

    eggNOGi COG2916.
    HOGENOMi HOG000218473.
    KOi K03746.
    OMAi NGENKTW.
    OrthoDBi EOG6NPM97.

    Enzyme and pathway databases

    BioCyci BAPH107806:GBZJ-272-MONOMER.

    Family and domain databases

    Gene3Di 1.10.287.1050. 1 hit.
    4.10.430.10. 1 hit.
    InterProi IPR027444. H-NS_C_dom.
    IPR001801. Histone_HNS.
    IPR027454. Histone_HNS_oligo_dom.
    [Graphical view ]
    Pfami PF00816. Histone_HNS. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002096. HnS. 1 hit.
    SMARTi SM00528. HNS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
      Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
      Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: APS.

    Entry informationi

    Entry nameiHNS_BUCAI
    AccessioniPrimary (citable) accession number: P57360
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: December 1, 2000
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
      Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3