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Protein

Flagellar biosynthesis protein FlhA

Gene

flhA

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis, Bacterial flagellum protein export, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar biosynthesis protein FlhA
Gene namesi
Name:flhA
Ordered Locus Names:BU241
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000001806 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 44HelicalSequence analysisAdd BLAST21
Transmembranei45 – 65HelicalSequence analysisAdd BLAST21
Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Transmembranei121 – 141HelicalSequence analysisAdd BLAST21
Transmembranei209 – 229HelicalSequence analysisAdd BLAST21
Transmembranei247 – 267HelicalSequence analysisAdd BLAST21
Transmembranei281 – 301HelicalSequence analysisAdd BLAST21
Transmembranei302 – 322HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001900121 – 696Flagellar biosynthesis protein FlhAAdd BLAST696

Interactioni

Protein-protein interaction databases

STRINGi107806.BU241.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105D7B. Bacteria.
COG1298. LUCA.
HOGENOMiHOG000254014.
KOiK02400.
OMAiETKELGW.

Family and domain databases

InterProiIPR025505. FHIPEP_CS.
IPR006301. FlhA.
IPR001712. T3SS_FHIPEP.
[Graphical view]
PfamiPF00771. FHIPEP. 1 hit.
[Graphical view]
PIRSFiPIRSF005419. FlhA. 1 hit.
PRINTSiPR00949. TYPE3IMAPROT.
TIGRFAMsiTIGR01398. FlhA. 1 hit.
PROSITEiPS00994. FHIPEP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57335-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINFSSLLRI VKSLKTTQWQ ILAGPILILM ILSMMVLPLA PFVLDVFFTF
60 70 80 90 100
NIALSIIILL VSMFTRHTLE FTAFPTILLF STLLRLALNV ASTRVIFLRG
110 120 130 140 150
HTGTNSAGRV IESFGHFLVG GNFAIGIVVF IILVIINFIV ITKGASRIAE
160 170 180 190 200
VGARFILDAM PGKQMAIDAD LNAGLIGEEK AKKRRIKITQ EADFYGSMDG
210 220 230 240 250
ASKFVRGDAI AGILIMVINI FGGLIIGLIQ HHMFLNKAVE VYTLLTIGDG
260 270 280 290 300
LVAQIPALVI STAAGVIVTR VSSNQNVGEQ MASQLFYNPQ VILLSAIVLG
310 320 330 340 350
VLGLVPGMPN IIFLVFTVLL FILSWWLYEK KYDLENDFIK SNKKYKFIHD
360 370 380 390 400
AISEASWNDV ELEDPIRIEI GYKLTPMTDI NKKGDLLDRI RIVRKKVAQE
410 420 430 440 450
IGFLPPLVRI KNNMHLSGNS YRIFIKGVEV GQGKCFYGRF MAIHSGRETE
460 470 480 490 500
SLPFEKVYEP TFGLSGYWID EEFKNKAQKK GYSVIESSVV LSTHLNFLIT
510 520 530 540 550
NHIDDLFGRQ EAQQLLERVT IDHPKLTEDL IPNTINLTIF HKILRNLLLE
560 570 580 590 600
HVPIRDMRTI LETLSEHADT QKDPNELTSI VRIALRKIII QKLFNQNNII
610 620 630 640 650
EIIGLEPNLE RLLLNSLKSG TDTIEPNLSE NLLIQTKEAI KKQLLIGSPL
660 670 680 690
VLLVRHSLRY FLSKFLRQNF PELTVLSQFE IIDVKEIKMT NIIGTS
Length:696
Mass (Da):78,304
Last modified:December 1, 2000 - v1
Checksum:i756F9A0919FA2B9D
GO

Sequence cautioni

The sequence BAB12956 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB12956.1. Different initiation.
RefSeqiNP_240070.2. NC_002528.1.
WP_010896024.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB12956; BAB12956; BAB12956.
GeneIDi1109684.
KEGGibuc:BU241.
PATRICi21244004. VBIBucAph127364_0254.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA. Translation: BAB12956.1. Different initiation.
RefSeqiNP_240070.2. NC_002528.1.
WP_010896024.1. NC_002528.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi107806.BU241.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB12956; BAB12956; BAB12956.
GeneIDi1109684.
KEGGibuc:BU241.
PATRICi21244004. VBIBucAph127364_0254.

Phylogenomic databases

eggNOGiENOG4105D7B. Bacteria.
COG1298. LUCA.
HOGENOMiHOG000254014.
KOiK02400.
OMAiETKELGW.

Family and domain databases

InterProiIPR025505. FHIPEP_CS.
IPR006301. FlhA.
IPR001712. T3SS_FHIPEP.
[Graphical view]
PfamiPF00771. FHIPEP. 1 hit.
[Graphical view]
PIRSFiPIRSF005419. FlhA. 1 hit.
PRINTSiPR00949. TYPE3IMAPROT.
TIGRFAMsiTIGR01398. FlhA. 1 hit.
PROSITEiPS00994. FHIPEP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFLHA_BUCAI
AccessioniPrimary (citable) accession number: P57335
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: November 2, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.